CAS 6450-77-7

Nicotinic acid-adenine dinucleotide

Description:

Nicotinic acid-adenine dinucleotide (NAD) is a coenzyme found in all living cells, playing a crucial role in various metabolic processes, particularly in redox reactions. It is composed of two nucleotides joined by their phosphate groups, with one nucleotide containing nicotinic acid (niacin) and the other containing adenine. NAD exists in two forms: oxidized (NAD+) and reduced (NADH), which are essential for cellular respiration and energy production. NAD+ acts as an electron carrier, facilitating the transfer of electrons in metabolic pathways such as glycolysis and the citric acid cycle. Additionally, NAD is involved in DNA repair, cell signaling, and the regulation of various enzymes. The substance is soluble in water and has a relatively high molecular weight. Its role in biological systems makes it a vital component for maintaining cellular health and function. Deficiencies in NAD can lead to metabolic disorders and have been linked to various health issues, emphasizing its importance in biochemistry and nutrition.

Formula: C₂₁H₂₆N₆O₁₅P₂

InChI: InChI=1S/C21H26N6O15P2/c22-17-12-18(24-7-23-17)27(8-25-12)20-16(31)14(29)11(41-20)6-39-44(36,37)42-43(34,35)38-5-10-13(28)15(30)19(40-10)26-3-1-2-9(4-26)21(32)33/h1-4,7-8,10-11,13-16,19-20,28-31H,5-6H2,(H4-,22,23,24,32,33,34,35,36,37)/t10-,11-,13-,14-,15-,16-,19-,20-/m1/s1

InChI key: InChIKey=SENPVEZBRZQVST-HISDBWNOSA-N

SMILES: O[C@H]1[C@H](N2C=3C(N=C2)=C(N)N=CN3)O[C@H](COP(OP(OC[C@H]4O[C@H]([C@H](O)[C@@H]4O)[N+]=5C=C(C([O-])=O)C=CC5)(=O)O)(=O)O)[C@H]1O

Synonyms:

• Pyridinium, 3-carboxy-1-β-D-ribofuranosyl-, hydroxide, 5′→5′-ester with adenosine 5′-(trihydrogen pyrophosphate), inner salt
• Adenosine 5′-(trihydrogen diphosphate), P′→5′-ester with 3-carboxy-1-β-D-ribofuranosylpyridinium, inner salt
• Codehydrogenase I, carboxy deamido analog
• Adenine-nicotinic acid dinucleotide
• 3-Carboxy-1-β-D-ribofuranosylpyridinium hydroxide, 5′-ester with adenosine 5′-pyrophosphate, inner salt

Nicotinic Acid Adenine Dinucleotide

CAS: 6450-77-7

Nicotinic Acid Adenine Dinucleotide is a precursor of NAD (Nicotinamide adenine dinucleotide) and a substrate for glutamine-dependent NAD+ synthase

Formula: C₂₁H₂₆N₆O₁₅P₂

Color and Shape: Soild

Molecular weight: 664.41

Ref: TM-T205954

Nicotinic Acid Adenine Dinucleotide

CAS: 6450-77-7

Nicotinic Acid Adenine Dinucleotide

Purity: ≥95%

Ref: 54-BUP22467

Nicotinic Acid Adenine Dinucleotide-d4

Controlled Product

CAS: 6450-77-7

Formula: C₂₁D₄H₂₂N₆O₁₅P₂

Color and Shape: Neat

Molecular weight: 668.434

Ref: TR-N429272