CAS 64506-49-6

Sofalcone

Description:

Sofalcone is a synthetic compound primarily used for its gastroprotective properties. It belongs to the class of compounds known as antiulcer agents and is often utilized in the treatment of gastric ulcers and related gastrointestinal disorders. Sofalcone functions by forming a protective barrier over the gastric mucosa, thereby shielding it from harmful substances such as gastric acid and pepsin. Its mechanism of action involves the stimulation of mucosal defense mechanisms, promoting the secretion of mucus and bicarbonate, which contribute to the maintenance of gastric integrity. The compound is characterized by its relatively low solubility in water, which can influence its bioavailability and therapeutic efficacy. Sofalcone is typically administered orally and is well-tolerated, with a favorable safety profile. However, like any medication, it may have potential side effects, and its use should be guided by a healthcare professional. Overall, Sofalcone represents a valuable option in the management of gastric mucosal injuries and ulcerative conditions.

Formula: C₂₇H₃₀O₆

InChI: InChI=1S/C27H30O6/c1-19(2)13-15-31-22-8-5-21(6-9-22)7-12-25(28)24-11-10-23(32-16-14-20(3)4)17-26(24)33-18-27(29)30/h5-14,17H,15-16,18H2,1-4H3,(H,29,30)

InChI key: InChIKey=GFWRVVCDTLRWPK-UHFFFAOYSA-N

SMILES: O(CC(O)=O)C1=C(C(C=CC2=CC=C(OCC=C(C)C)C=C2)=O)C=CC(OCC=C(C)C)=C1

Synonyms:

• ({5-[(3-methylbut-2-en-1-yl)oxy]-2-[(2E)-3-{4-[(3-methylbut-2-en-1-yl)oxy]phenyl}prop-2-enoyl]phenyl}oxy)acetic acid
• 2-[5-[(3-Methyl-2-buten-1-yl)oxy]-2-[3-[4-[(3-methyl-2-buten-1-yl)oxy]phenyl]-1-oxo-2-propen-1-yl]phenoxy]acetic acid
• Acetic acid, 2-[5-[(3-methyl-2-buten-1-yl)oxy]-2-[3-[4-[(3-methyl-2-buten-1-yl)oxy]phenyl]-1-oxo-2-propen-1-yl]phenoxy]-
• Acetic acid, [5-[(3-methyl-2-butenyl)oxy]-2-[3-[4-[(3-methyl-2-butenyl)oxy]phenyl]-1-oxo-2-propenyl]phenoxy]-
• Solon
• Su 88
• [5-[(3-Methyl-2-butenyl)oxy]-2-[3-[4-[(3-methyl-2-butenyl)oxy]phenyl]-1-oxo-2-propenyl]phenoxy]acetic Acid
• acetic acid, 2-[5-[(3-methyl-2-buten-1-yl)oxy]-2-[(2E)-3-[4-[(3-methyl-2-buten-1-yl)oxy]phenyl]-1-oxo-2-propen-1-yl]phenoxy]-
• acetic acid, [5-[(3-methyl-2-butenyl)oxy]-2-[(2E)-3-[4-[(3-methyl-2-butenyl)oxy]phenyl]-1-oxo-2-propenyl]phenoxy]-
• {5-[(3-Methyl-2-buten-1-yl)oxy]-2-[(2E)-3-{4-[(3-methyl-2-buten-1-yl)oxy]phenyl}-2-propenoyl]phenoxy}acetic acid
• {5-[(3-Methylbut-2-en-1-yl)oxy]-2-[(2E)-3-{4-[(3-methylbut-2-en-1-yl)oxy]phenyl}prop-2-enoyl]phenoxy}acetic acid

Acetic acid,[5-[(3-methyl-2-butenyl)oxy]-2-[3-[4-[(3-methyl-2-butenyl)oxy]phenyl]-1-oxo-2-propenyl]phenoxy]-

CAS: 64506-49-6

Formula: C₂₇H₃₀O₆

Purity: 97%

Color and Shape: Solid

Molecular weight: 450.5235

Ref: IN-DA00IBDO

Sofalcone

CAS: 64506-49-6

Sofalcone

Formula: C₂₇H₃₀O₆

Purity: >98%

Molecular weight: 450.52

Ref: 54-OR1029304

(E)-Sofalcone-d4

CAS: 153175-87-2, 153175-94-1, 64506-49-6

Formula: C₂₇H₂₆D₄O₆

Molecular weight: 454.56

Ref: 4Z-S-248002

Sofalcone

CAS: 64506-49-6

Sofalcone

Formula: C₂₇H₃₀O₆

Purity: ≥95%

Molecular weight: 450.52

Ref: 54-BUP17527

Sofaclone

CAS: 64506-49-6

Ref: 7W-GP3840

Sofalcone

CAS: 64506-49-6

Formula: C₂₇H₃₀O₆

Purity: >98.0%(T)(HPLC)

Color and Shape: White to Light yellow powder to crystal

Molecular weight: 450.53

Ref: 3B-M3730

Sofalcone

CAS: 64506-49-6

2-(5-((3-Methylbut-2-en-1-yl)oxy)-2-(3-(4-((3-methylbut-2-en-1-yl)oxy)phenyl)acryloyl)phenoxy)acetic acid

Formula: C₂₇H₃₀O₆

Purity: 97%

Molecular weight: 450.52

Ref: IN-DG151690

Sofalcone

CAS: 64506-49-6

Sofalcone (SU-88), a gastric antiulcer agent in clinical use, is known to induce the expression of Heme oxygenase-1 (HO-1) in gastric epithelium.

Formula: C₂₇H₃₀O₆

Purity: 97.55%

Color and Shape: Solid

Molecular weight: 450.52

Ref: TM-T4977

Sofalcone

Controlled Product

CAS: 64506-49-6

Applications Sofalcone is a substituted chalcone with anti-ulcer activity.
References Matsuo, Y., et al.: Arzneim. Forsch., 33, 242 (1983), Suwa, T., et al.: Jpn. J. Pharmacol., 35, 47 (1984),

Formula: C₂₇H₃₀O₆

Color and Shape: Neat

Molecular weight: 450.52

Ref: TR-S675500

Sofalcone

CAS: 64506-49-6

Increases VEGF via heme oxygenase-1 modulation; anti-ulcer agent

Formula: C₂₇H₃₀O₆

Purity: Min. 95%

Color and Shape: Yellow Powder

Molecular weight: 450.52 g/mol

Ref: 3D-FS27851

SOFALCONE

CAS: 64506-49-6

Purity: 97%

Molecular weight: 450.5310059

Ref: 10-F835711