CAS 6452-71-7

Oxprenolol

Description:

Oxprenolol is a non-selective beta-adrenergic antagonist, commonly used in the treatment of hypertension and certain cardiac conditions. It functions by blocking the action of catecholamines like adrenaline on beta-adrenergic receptors, leading to a decrease in heart rate and blood pressure. Chemically, it is characterized by its structure, which includes a phenolic hydroxyl group and a propanolamine moiety, contributing to its pharmacological activity. Oxprenolol exhibits moderate lipophilicity, allowing it to cross biological membranes effectively. It is typically administered orally and has a relatively short half-life, necessitating multiple doses throughout the day for sustained therapeutic effects. The substance may also exhibit some intrinsic sympathomimetic activity, which can lead to a less pronounced reduction in heart rate compared to other beta-blockers. As with many medications, potential side effects include fatigue, dizziness, and gastrointestinal disturbances, and it should be used with caution in patients with respiratory conditions due to its non-selective nature. Overall, Oxprenolol represents an important option in the management of cardiovascular diseases.

Formula: C₁₅H₂₃NO₃

InChI: InChI=1S/C15H23NO3/c1-4-9-18-14-7-5-6-8-15(14)19-11-13(17)10-16-12(2)3/h4-8,12-13,16-17H,1,9-11H2,2-3H3

InChI key: InChIKey=CEMAWMOMDPGJMB-UHFFFAOYSA-N

SMILES: O(CC(CNC(C)C)O)C1=C(OCC=C)C=CC=C1

Synonyms:

• (.+-.)-Oxprenolol
• 1-(2-Allyloxy-phenoxy)-3-isopropylamino-propan-2-ol
• 1-(Isopropylamino)-2-hydroxy-3-[o-(allyloxy)phenoxy]propane
• 1-(Propan-2-ylamino)-3-(2-prop-2-enoxyphenoxy)propan-2-ol
• 1-[(1-Methylethyl)amino]-3-[2-(2-propen-1-yloxy)phenoxy]-2-propanol
• 1-[o-(Allyloxy)phenoxy]-3-(isopropylamino)-2-propanol
• 2-Propanol, 1-[(1-methylethyl)amino]-3-[2-(2-propen-1-yloxy)phenoxy]-
• 2-Propanol, 1-[o-(allyloxy)phenoxy]-3-(isopropylamino)-
• Coretal
• dl-Oxprenolol
• 1-(2-allyloxyphenoxy)-3-isopropylaminopropan-2-ol
• 2-Propanol, 1-[(1-methylethyl)amino]-3-[2-(2-propenyloxy)phenoxy]-
• Oxprenolol-d7
• Aids-001596
• 1-(Isopropylamino)-3-[2-(2-propenyloxy)phenoxy]-2-propanol
• 6452-73-9 (Hydrochloride)
• 2-Propanol, 1-[o-(allyloxy)phenoxy]-3-(isopropylamino)- (7CI, 8CI)
• 2-Propanol, 1-[(1-methylethyl)amino]-3-[2-(2-propenyloxy)phenoxy]- (9CI)
• Aids001596
• 1-(2-Allyloxyphenoxy)-3-(isopropylamino)-2-propanol
• 1-[2-(Allyloxy)phenoxy]-3-(isopropylamino)-2-propanol

Oxprenolol

CAS: 6452-71-7

Formula: C₁₅H₂₃NO₃

Color and Shape: White To Off-White Solid

Molecular weight: 265.35

Ref: 4Z-O-151

Oxprenolol

Controlled Product

CAS: 6452-71-7

Applications Oxprenolol is a free base of Oxprenolol Hydrochloride(O870500) which is a β-Adrenergic blocker. Antihypertensive, antianginal, antiarrhythmic.
References Garteiz, et al.: J. Pharmacol. Exp. Ther., 179, 354 (1971), Taylor, S.H., et al.: N. Engl. J. Med., 307, 1293 (1982),

Formula: C₁₅H₂₃NO₃

Color and Shape: White To Off-White

Molecular weight: 265.35

Ref: TR-O871500

Oxprenolol

CAS: 6452-71-7

Oxprenolol is a kinase inhibitor that has been shown to have potential as an anti-cancer drug. It works by inhibiting the activity of kinases, which are enzymes that play a role in cell growth and division. Oxprenolol has been studied extensively in Chinese hamster ovary cells and human cancer cell lines, where it has been shown to induce apoptosis and inhibit tumor growth. This drug is also used to treat hypertension and angina pectoris due to its ability to block the effects of the hormone adrenaline on the heart. Oxprenolol is excreted primarily in urine and is available in tablet form, which contains cellulose as an inactive ingredient. This drug may interact with other medications such as voriconazole or angiotensin-converting enzyme inhibitors, so it should be used with caution in patients taking these drugs.

Formula: C₁₅H₂₃NO₃

Purity: Min. 95%

Molecular weight: 265.35 g/mol

Ref: 3D-GAA45271