CAS 6452-73-9

oxprenolol hydrochloride

Description:

Oxprenolol hydrochloride is a non-selective beta-adrenergic antagonist, primarily used in the treatment of hypertension and certain cardiac conditions. It functions by blocking the action of catecholamines on beta-adrenergic receptors, leading to a decrease in heart rate and blood pressure. This compound is characterized by its ability to cross the blood-brain barrier, which can result in central nervous system effects. Chemically, it is a white to off-white crystalline powder that is soluble in water and exhibits a pH range that is typically neutral. Oxprenolol hydrochloride has a moderate bioavailability and is metabolized primarily in the liver, with its pharmacokinetics influenced by factors such as age and liver function. Side effects may include fatigue, dizziness, and gastrointestinal disturbances, which are common to beta-blockers. As with any medication, it is essential to use oxprenolol hydrochloride under medical supervision to monitor for potential adverse effects and interactions with other drugs.

Formula: C₁₅H₂₄ClNO₃

InChI: InChI=1/C15H23NO3.ClH/c1-4-9-18-14-7-5-6-8-15(14)19-11-13(17)10-16-12(2)3;/h4-8,12-13,16-17H,1,9-11H2,2-3H3;1H

InChI key: InChIKey=COAJXCLTPGGDAJ-UHFFFAOYSA-N

SMILES: O(CC(CNC(C)C)O)C1=C(OCC=C)C=CC=C1.Cl

Synonyms:

• (±)-1-[o-(Allyloxy)phenoxy]-3-isopropylamino-2-propanol hydrochloride
• 1-(2-Allyloxyphenoxy)-2-hydroxy-3-isopropylaminopropane hydrochloride
• 1-(o-Allyloxyphenoxy)-3-isopropylamino-2-propanol hydrochloride
• 1-(o-Allyloxyphenoxy)-3-isopropylamino-2-propranol-hydrochloride
• 1-Isopropyl-amino-2-hydroxy-3-(O-allyloxyphenoxy)propane hydrochloride
• 1-Isopropylamino-3-(o-allyloxyphenoxy)-2-propanol hydrochloride
• 2-(o-Allyloxyphenoxy)-2-hydroxy-N-isopropyl-1-propylamine hydrochloride
• 2-Propanol, 1-((1-methylethyl)amino)-3-(2-(2-propenyloxy)phenoxy)-, hydrochloride
• 2-Propanol, 1-(o-allyloxyphenoxy)-3-isopropylamino-, hydrochloride
• 2-Propanol, 1-[(1-methylethyl)amino]-3-[2-(2-propen-1-yloxy)phenoxy]-, hydrochloride (1:1)
• 2-Propanol, 1-[o-(allyloxy)phenoxy]-3-(isopropylamino)-, hydrochloride
• Ba 39089
• C-39089-Ba
• Ccris 1097
• Ciba 39089Ba
• Coretal
• Drospfta
• Evinrozit
• Flecor
• Laracor
• Oxiprenolol hydrochloride
• Oxprenolol HCl
• Oxprenolol hydrochloride [USAN:JAN]
• Paritane
• Ranidrox
• Rixiprol
• Secondafil
• Slow-Pren
• Slow-Trasicor
• Trasacor
• Trasicor
• Trasicor 80
• Trepress
• Unii-F4Xsi7Sniu
• Vrachor
• dl-Alprenolol hydrochloride
• dl-Oxprenolol hydrochloride
• ome
• Oxprenolol hydrochloride
• LABOTEST-BB LT00772178
• 1-[2-(ALLYLOXY)PHENOXY]-3-[ISOPROPYLAMINO]-2-PROPANOL HYDROCHLORIDE
• 1-[2-ALLYLOXYPHENOXY]-3-[ISOPROPYLAMINO]-2-PROPANOLHCl
• 2-Propanol, 1-[(1-methylethyl)amino]-3-[2-(2-propenyloxy)phenoxy]-, hydrochloride (9CI)
• 1-(o-allyloxyphenoxy)-3-isopropylamino-2-propanohydrochloride
• 1-(o-allyloxyphenoxy)-3-isopropylaminopropan-2-olhydrochloride
• 2-Propanol, 1-[o-(allyloxy)phenoxy]-3-(isopropylamino)-, hydrochloride (7CI, 8CI)
• 2-(o-allyloxyphenoxy)-2-hydroxy-n-isopropyl-1-propylaminehydrochloride

Oxprenolol Hydrochloride

CAS: 6452-73-9

Color and Shape: Neat

Ref: 61-FOR0129.00

Oxprenolol Hydrochloride 1.0 mg/ml in Methanol (as free base)

CAS: 6452-73-9

Color and Shape: Single Solution

Ref: 61-AMP0129.00-01

OXPRENOLOL HYDROCHLORIDE CRS

CAS: 6452-73-9

OXPRENOLOL HYDROCHLORIDE CRS

Formula: C₁₅H₂₄ClNO₃

Color and Shape: Crystalline Powder. White. Powder.

Molecular weight: 301.809

Ref: 41-O0250000

Oxprenolol Hydrochloride

CAS: 6452-73-9

Aromatic drugs of amino-alcohols, other than those contg more than one kind of oxygen function, their ethers and esters; salts thereof, nesoi

Formula: C₁₅H₂₃NO₃·HCI

Color and Shape: White Powder

Molecular weight: 405.08009

Ref: 45-1483505

Oxprenolol hydrochloride

CAS: 6452-73-9

Formula: C₁₅H₂₄ClNO₃

Purity: ≥ 98.0%

Color and Shape: White solid

Molecular weight: 301.81

Ref: 7W-GP2740

Oxprenolol Hydrochloride

Controlled Product

CAS: 6452-73-9

Formula: C₁₅H₂₃NO₃·ClH

Color and Shape: Neat

Molecular weight: 301.81

Ref: 86-MM0129.00

Oxprenolol hydrochloride

Controlled Product

CAS: 6452-73-9

Formula: C₁₅H₂₃NO₃·ClH

Color and Shape: Neat

Molecular weight: 301.81

Ref: 04-CA15789305

Oxprenolol Hydrochloride

CAS: 6452-73-9

Applications β-Adrenergic blocker. Antihypertensive, antianginal, antiarrhythmic.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Garteiz, et al.: J. Pharmacol. Exp. Ther., 179, 354 (1971), Taylor, S.H., et al.: N. Engl. J. Med., 307, 1293 (1982),

Formula: C₁₅H₂₃NO₃·ClH

Color and Shape: White

Molecular weight: 301.81

Ref: TR-O870500

Oxprenolol Hydrochloride

CAS: 6452-73-9

Formula: C₁₅H₂₃NO₃HCl

Molecular weight: 265.35 : 36.46

Ref: ST-EA-CP-O74001

Oxprenolol hydrochloride

Controlled Product

CAS: 6452-73-9

Oxprenolol hydrochloride is a cardioselective β-adrenergic receptor antagonist that blocks the action of epinephrine, norepinephrine, and other sympathomimetics on cardiac muscle. It has been shown to have a hypoglycemic effect at an optimum concentration of 0.25 mg/kg. The matrix effect is the increase in apparent volume of distribution due to binding to plasma proteins, which can be used to calculate the clearance rate and bioavailability. The median plasma concentration for oxprenolol was determined in patients with congestive heart failure (CHF) and was found to be approximately twice that of healthy subjects. Oxprenolol binds with high affinity to human serum albumin, α1-acid glycoprotein, and β2-glycoprotein I. This drug also has been shown to inhibit biological processes such as immune responses in autoimmune diseases by inhibiting T-cell activation or proliferation.

Formula: C₁₅H₂₃NO₃•HCl

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 301.82 g/mol

Ref: 3D-GAA45273