CAS 64520-05-4

(5E)-5-[3-(dimethylamino)propylidene]-10,11-dihydro-5H-dibenzo[a,d][7]annulen-10-ol

Description:

The chemical substance known as (5E)-5-[3-(dimethylamino)propylidene]-10,11-dihydro-5H-dibenzo[a,d][7]annulen-10-ol, with the CAS number 64520-05-4, is a complex organic compound characterized by its unique molecular structure, which includes a dibenzo[a,d]annulene core. This compound features a dimethylamino group, which contributes to its potential biological activity and solubility properties. The presence of the propylidene moiety suggests that it may exhibit interesting reactivity and could participate in various chemical reactions, including those typical of alkenes. The hydroxyl group (–OH) indicates that it may have alcohol-like properties, potentially influencing its interactions with other molecules. This compound may be of interest in medicinal chemistry due to its structural features, which could lead to specific pharmacological effects. However, detailed studies would be necessary to fully elucidate its properties, including its stability, reactivity, and potential applications in various fields such as pharmaceuticals or materials science.

Formula: C₂₀H₂₃NO

InChI: InChI=1/C20H23NO/c1-21(2)13-7-12-17-16-9-4-3-8-15(16)14-20(22)19-11-6-5-10-18(17)19/h3-6,8-12,20,22H,7,13-14H2,1-2H3/b17-12+

Synonyms:

• 5H-Dibenzo(a,d)cyclohepten-10-ol, 5-(3-(dimethylamino)propylidene)-10,11-dihydro-
• 5H-Dibenzo(a,d)cyclohepten-10-ol, 5-(3-(dimethylamino)propylidene)-10,11-dihydro-, (E)-

10-Hydroxy (E)-Amitriptyline

Controlled Product

CAS: 64520-05-4

Stability Hygroscopic
Applications (5E)-5-[3-(dimethylamino)propylidene]-10,11-dihydro-5H-dibenzo[a,d]cyclohepten-10-ol is a metabolite of amitriptyline (A633350) which is a dibenzocycloheptadiene derivative and an antidepressant (1). Amitriptyline is also a TrkA and TrkB receptor agonist and exhibits neurotrophic and anti-inflammatory activities (2,3). Drinking water contaminant candidate list 3 (CCL 3) compound as per United States Environmental Protection Agency (EPA).

Formula: C₂₀H₂₃NO

Color and Shape: Neat

Molecular weight: 293.4

Ref: TR-D462790

(E)-10-Hydroxyamitriptyline

CAS: 64520-05-4

Amitriptyline is a tricyclic antidepressant that is used to treat depression and anxiety. Amitriptyline is metabolized in the liver by demethylation, which produces its active form, (E)-10-hydroxyamitriptyline. The metabolism of amitriptyline can be monitored by following the levels of its metabolites in urine or plasma samples. The concentration of amitriptyline and its metabolites can vary in different types of water samples such as industrial wastewater, water from wastewater treatment plants, and drinking water. Amitriptyline may also affect human serum hormones and cause changes in the body's phenotype.

Formula: C₂₀H₂₃NO

Purity: Min. 95%

Molecular weight: 293.4 g/mol

Ref: 3D-FH178735

Amitriptyline EP Impurity F

CAS: 64520-05-4

Formula: C₂₀H₂₃NO

Molecular weight: 293.40

Ref: ST-EA-CP-A39006