CAS 6453-67-4

pyropheophorbide A methyl ester

Description:

Pyropheophorbide A methyl ester is a chlorophyll derivative characterized by its unique structure, which includes a modified porphyrin ring system. This compound is typically a dark green to brown solid, exhibiting strong absorption in the visible light spectrum, particularly in the red and near-infrared regions. It is soluble in organic solvents such as chloroform and methanol but has limited solubility in water. Pyropheophorbide A methyl ester is notable for its applications in photodynamic therapy, where it serves as a photosensitizer due to its ability to generate reactive oxygen species upon light activation. Additionally, it is used in various research contexts, including studies on chlorophyll degradation and the role of chlorophyll derivatives in photosynthesis. The compound's stability and reactivity can be influenced by environmental factors such as pH and light exposure, making it an interesting subject for both practical applications and theoretical studies in photochemistry and biochemistry.

Formula: C₃₄H₃₆N₄O₃

InChI: InChI=1/C34H36N4O3/c1-8-20-16(3)24-13-26-18(5)22(10-11-31(40)41-7)33(37-26)23-12-30(39)32-19(6)27(38-34(23)32)15-29-21(9-2)17(4)25(36-29)14-28(20)35-24/h8,13-15,18,22,35-36H,1,9-12H2,2-7H3/b24-13-,25-14-,26-13-,27-15-,28-14-,29-15-,33-23-

SMILES: C=Cc1c(C)c2=CC3=NC(=C4CC(=O)C5=C(C)C(=Cc6c(CC)c(C)c(C=c1[nH]2)[nH]6)N=C45)C(CCC(=O)OC)C3C

Synonyms:

• 3-Phorbinepropanoic acid, 9-ethenyl-14-ethyl-4,8,13,18-tetramethyl-20-oxo-, methyl ester, (3S,4S)-
• Pyrophaeophorbide-a-monomethyl ester
• Methyl 4-(9-Ethenyl-14-Ethyl-4,8,13-Trimethyl-20-Oxophorbin-3-Yl)Butanoate
• Methyl 3-(9-Ethenyl-14-Ethyl-4,8,13,18-Tetramethyl-20-Oxo-24,25-Dihydrophorbin-3-Yl)Propanoate
• Methyl pyropheophorbide-a

MPP A

CAS: 6453-67-4

Formula: C₃₄H₃₆N₄O₃

Purity: 97%

Color and Shape: Solid

Molecular weight: 548.6746

Ref: IN-DA00ED9Z

Methyl pyropheophorbide-a

CAS: 6453-67-4

Methyl pyropheophorbide-a

Purity: ≥98%

Molecular weight: 548.67g/mol

Ref: 54-BUP21780

Pyropheophorbide a methyl ester

CAS: 6453-67-4

Formula: C₃₄H₃₆N₄O₃

Molecular weight: 548.67

Ref: 7W-GL8875

Pyropheophorbide-a methyl ester

CAS: 6453-67-4

Formula: C₃₄H₃₆N₄O₃

Purity: 95%

Molecular weight: 548.69

Ref: FT-MPPa

Methyl pyropheophorbide-a

CAS: 6453-67-4

MPPa, a PDT photosensitizer derived from chlorophyll a, absorbs at 667/674 nm with no dark cytotoxicity.

Formula: C₃₄H₃₆N₄O₃

Purity: 98.17%

Color and Shape: Solid

Molecular weight: 548.67

Ref: TM-T33492

Pyropheophorbide A Methyl Ester

Controlled Product

CAS: 6453-67-4

Stability Light Sensitive
Applications Pyropheophorbide A Methyl Ester is a chlorophyll (C379815) analog for studies of photosynthesis. Methyl pyropheophorbide a (Pyropheophorbide-a methyl ester), a chlorophyll-a derivative, and is a potent photosensitizer that can be used in photodynamic therapy (PDT) of cancer. Methyl pyropheophorbide a has photodynamic activity and can induce apoptosis and inhibit tumor growth.
References Bensasson, R., et al.: Nature, 290, 329 (1981); Moore, A., et al.: Science, 216, 982 (1982)

Formula: C₃₄H₃₆N₄O₃

Color and Shape: Neat

Molecular weight: 548.67

Ref: TR-P998865