CAS 64544-07-6: Cefuroxime axetil
Description:Cefuroxime axetil is a broad-spectrum cephalosporin antibiotic used primarily to treat bacterial infections. It is a prodrug, meaning it is converted into its active form, cefuroxime, after administration. This compound is characterized by its ability to inhibit bacterial cell wall synthesis, making it effective against a variety of Gram-positive and Gram-negative bacteria. Cefuroxime axetil is typically administered orally and is known for its good bioavailability compared to other cephalosporins. The substance is generally stable in acidic environments, which enhances its absorption in the gastrointestinal tract. It is often used to treat respiratory tract infections, skin infections, and urinary tract infections. Common side effects may include gastrointestinal disturbances, allergic reactions, and, in rare cases, more severe hypersensitivity reactions. As with all antibiotics, it is crucial to use cefuroxime axetil judiciously to prevent the development of antibiotic resistance.
Formula:C20H22N4O10S
InChI:InChI=1S/C20H22N4O10S/c1-9(25)33-10(2)34-19(28)15-11(7-32-20(21)29)8-35-18-14(17(27)24(15)18)22-16(26)13(23-30-3)12-5-4-6-31-12/h4-6,10,14,18H,7-8H2,1-3H3,(H2,21,29)(H,22,26)/b23-13-/t10?,14-,18-/m1/s1
InChI key:InChIKey=KEJCWVGMRLCZQQ-YJBYXUATSA-N
SMILES:O=C(OCC1=C(C(=O)OC(OC(=O)C)C)N2C(=O)C(NC(=O)C(=NOC)C=3OC=CC3)C2SC1)N
- Synonyms:
- 1-(acetyloxy)ethyl (6R,7R)-3-[(carbamoyloxy)methyl]-7-{[(2E)-2-furan-2-yl-2-(methoxyimino)acetyl]amino}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
- 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 3-(((aminocarbonyl)oxy)methyl)-7-((2-furanyl(methoxyimino)a cetyl)-amino)-8-oxo-, 1-(acetyloxy)ethyl ester, (6R-(6alpha,7beta(Z)))-
- 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 3-[[(aminocarbonyl)oxy]methyl]-7-[[(2Z)-2-(2-furanyl)-2-(methoxyimino)acetyl]amino]-8-oxo-, 1-(acetyloxy)ethyl ester, (6R,7R)-
- 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 3-[[(aminocarbonyl)oxy]methyl]-7-[[(2Z)-2-furanyl(methoxyimino)acetyl]amino]-8-oxo-, 1-(acetyloxy)ethyl ester, (6R,7R)-
- 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 3-[[(aminocarbonyl)oxy]methyl]-7-[[2-furanyl(methoxyimino)acetyl]amino]-8-oxo-, 1-(acetyloxy)ethyl ester, [6R-[6α,7β(Z)]]-
- Altacef
- Axoril
- Bioracef
- Bioxime
- Cci 15641
- See more synonyms
- Cefaks
- Cefazine
- Ceftin
- Cefurax
- Cefuroxime 1-Acetoxymethyl Ester
- Cefuroxime 1-acetoxyethyl ester
- Cefuroxine 1-acetoxyethyl ester
- Cepazine
- Elobact
- Forcef
- Kefurox
- Oraxim
- Ximos
- Xorimax
- Zinacef
- Zinat
- Zinnat
- Cefuroxime axetil
