CAS 6456-44-6

Pyridinium, 3-(aminocarbonyl)-1-methyl-, iodide (1:1)

Description:

Pyridinium, 3-(aminocarbonyl)-1-methyl-, iodide (1:1), commonly referred to as a pyridinium salt, is a quaternary ammonium compound characterized by its pyridine ring structure substituted with an aminocarbonyl group and a methyl group. This compound typically exhibits a white to off-white crystalline appearance and is soluble in polar solvents such as water and alcohols due to its ionic nature. The presence of the iodide ion contributes to its solubility and can influence its reactivity and stability. Pyridinium salts are known for their ability to act as strong electrophiles, making them useful in various organic synthesis reactions. Additionally, the aminocarbonyl group can participate in hydrogen bonding, enhancing the compound's interactions with other molecules. The compound's properties, including melting point, boiling point, and reactivity, can vary based on environmental conditions and the presence of other chemical species. Overall, this substance is of interest in both synthetic organic chemistry and potential applications in pharmaceuticals.

Formula: C₇H₉N₂O·I

InChI: InChI=1S/C7H8N2O.HI/c1-9-4-2-3-6(5-9)7(8)10;/h2-5H,1H3,(H-,8,10);1H

InChI key: InChIKey=IWEIZMCTGMHCRE-UHFFFAOYSA-N

SMILES: C(N)(=O)C1=C[N+](C)=CC=C1.[I-]

Synonyms:

• 3-(Aminocarbonyl)-1-methylpyridinium iodide
• 3-Carbamoyl-1-Methylpyridinium
• 3-Carbamoyl-1-methylpyridinium iodide
• N'-{3-[(2,3-dihydro-1H-inden-5-yloxy)methyl]benzoyl}-2,6-dimethoxybenzohydrazide
• Nicotinamide methiodide
• Nsc 23359
• Pyridinium, 3-(aminocarbonyl)-1-methyl-, iodide
• Pyridinium, 3-(aminocarbonyl)-1-methyl-, iodide (1:1)
• Pyridinium, 3-carbamoyl-1-methyl-, iodide
• Pyridinium, 3-carbamoyl-1-methyl-, iodide (8CI)
• Pyridinium, 3-carbamyl-1-methyl-, iodide
• 1-Methylnicotinamide iodide
• 3-(aminocarbonyl)-1-methylpyridiniumiodide
• 1-methylpyridine-5-carboxamide iodide
• 1-Methyl-3-carbamoylpyridinium·iodide
• nicotinamidemethiodide
• N-METHYLNICOTINAMIDE IODIDE
• 1-METHYLNICOTINAMIDE IODIDE SALT
• 1-METHYL-NICOTINAMIDE IODIDE
• 3-carbamoyl-1-methylpyridiniumiodide
• 3-(aminocarbonyl)-1-methyl-pyridiniuiodide
• LABOTEST-BB LT00233117
• N-METHYLNICOTINIC ACID AMIDE IODIDE SALT

4-Iodo-1-methyl-1,2-dihydropyridine-3-carboxamide

CAS: 6456-44-6

Formula: C₇H₉IN₂O

Purity: 98%

Color and Shape: Solid

Molecular weight: 264.0636

Ref: IN-DA003EIR

1-Methylnicotinamide-13C-d3 Iodide

CAS: 6456-44-6

Formula: C₆₁₃CH₆D₃N₂O·I

Color and Shape: Pale Yellow Solid

Molecular weight: 141.17 126.91

Ref: 4Z-N-133004

3-Carbamoyl-1-methylpyridin-1-ium iodide

CAS: 6456-44-6

3-Carbamoyl-1-methylpyridin-1-ium iodide

Purity: 98%

Molecular weight: 264.06g/mol

Ref: 54-OR92560

1-Methylnicotinamide Iodide

CAS: 6456-44-6

Formula: C₇H₉N₂O·I

Color and Shape: Pale Yellow Solid

Molecular weight: 137.16 126.91

Ref: 4Z-N-133003

1-Methylnicotinamide Iodide

Controlled Product

CAS: 6456-44-6

Formula: C₇H₉N₂O·I

Color and Shape: Neat

Molecular weight: 264.06

Ref: 86-MM0552.05

1-Methyl-nicotinamide Iodide

Controlled Product

CAS: 6456-44-6

Applications A nicotinic acid derivative which shows a dopaminergic neurotoxicity.
References Rollema, H., et al.: J. Med. Chem., 33, 2221 (1990),

Formula: C₇H₉IN₂O

Color and Shape: Neat

Molecular weight: 264.06

Ref: TR-M323235

1-Methylnicotinamide-d3 Iodide

Controlled Product

CAS: 6456-44-6

Applications 3-(Aminocarbonyl)-1-methylpyridinium-d3 Iodide is the isotope labelled derivative of 1-Methylnicotinamide (M323235), a nicotinic acid derivative which shows a dopaminergic neurotoxicity.
References Rollema, H., et al.: J. Med. Chem., 33, 2221 (1990),

Formula: C₇H₆D₃IN₂O

Color and Shape: Light Yellow

Molecular weight: 267.08

Ref: TR-M323237

3-Carbamoyl-1-methylpyridin-1-ium iodide

CAS: 6456-44-6

Purity: 98%

Molecular weight: 264.0660095

Ref: 10-F791031

1-Methyl-nicotinamide iodide

CAS: 6456-44-6

1-Methyl-nicotinamide iodide is a drug that has been used in clinical trials for the treatment of type 2 diabetes mellitus. It is thought to work by increasing the sensitivity of cells to insulin, which may be related to its ability to bind to protein amide groups and form hydrogen bonds with the amino acid side chains. The compound also has been shown to increase the activity of the enzyme glycogen synthase in rats. 1-Methyl-nicotinamide iodide is soluble in water and human serum, and shows low solubility in ethanol. It has not been studied in humans, but animal studies have shown that it can be absorbed orally and metabolized into hippuric acid, which is excreted as a metabolic product through urine. Animal studies also showed that 1-methyl-nicotinamide iodide inhibits glucose production by pancreatic beta cells, which may lead to an increased insulin response after eating.

Formula: C₇H₉IN₂O

Purity: Min. 95%

Color and Shape: Off-White Powder

Molecular weight: 264.06 g/mol

Ref: 3D-FM25888

3-Carbamoyl-1-methylpyridin-1-ium iodide monohydrate

CAS: 6456-44-6

Formula: C₇H₉IN₂O

Purity: 96%

Molecular weight: 264.066

Ref: 10-F181849

1-Methylnicotinamide Iodide

CAS: 6456-44-6

Color and Shape: Neat

Ref: 61-FOR0552.05