CAS 64605-23-8

1-(2-aminophenyl)-2-chloroethanone

Description:

1-(2-Aminophenyl)-2-chloroethanone, with the CAS number 64605-23-8, is an organic compound characterized by its structure, which includes an amino group and a chloroethanone moiety. This compound typically appears as a solid or crystalline substance and is known for its potential applications in medicinal chemistry and as an intermediate in organic synthesis. The presence of the amino group suggests that it may exhibit basic properties, while the chloroethanone part can participate in nucleophilic substitution reactions. Its reactivity is influenced by the electron-withdrawing nature of the chloro group, which can enhance the electrophilicity of the carbonyl carbon. Additionally, the compound may exhibit biological activity, making it of interest in pharmaceutical research. Safety data should be consulted, as compounds containing chlorine and amine functionalities can pose health risks, including toxicity and irritant properties. Overall, 1-(2-aminophenyl)-2-chloroethanone is a compound of interest in both synthetic and medicinal chemistry contexts.

Formula: C₈H₈ClNO

InChI: InChI=1/C8H8ClNO/c9-5-8(11)6-3-1-2-4-7(6)10/h1-4H,5,10H2

SMILES: c1ccc(c(c1)C(=O)CCl)N

Synonyms:

• Ethanone, 1-(2-Aminophenyl)-2-Chloro-
• 1-(2-Aminophenyl)-2-chloroethanone

1-(2-Aminophenyl)-2-chloroethanone

CAS: 64605-23-8

Formula: C₈H₈ClNO

Purity: 95.0%

Molecular weight: 169.61

Ref: 10-F431378

1-(2-Aminophenyl)-2-chloroethanone-13C8

Controlled Product

CAS: 64605-23-8

Applications 1-(2-Aminophenyl)-2-chloroethanone-13C8 is an intermediate in the synthesis of Indole-3-carboxaldehyde-13C8 (I614993), the labelled version of Indole-3-carboxaldehyde (I615020) which is a tryptophan (T947200) metabolite from Streptomyces staurosporeus and it is chemical constituent from Inula wissmanniana. Indole-3-carboxaldehyde and other tryptophan metabolites play an important role in mammalian gut immune homeostasis.
References Yang, S., et al.: J. Nat. Prod., 60, 44 (1997); Cheng, X. et al.: Chem. Nat. Compd., 49, 815 (2013); Zelante, T., et al,: Immunity, 39, 372 (2013)

Formula: C₈H₈ClNO

Color and Shape: Neat

Molecular weight: 177.549

Ref: TR-A628052

1-(2-Aminophenyl)-2-chloroethanone

Controlled Product

CAS: 64605-23-8

Applications 1-(2-Aminophenyl)-2-chloroethanone is a reagent in the synthesis of 4-(2-Aminophenyl)-4-oxo-2-butenoic Acid (A638220) which is a novel human lens metabolite from normal and cataractous human lenses. A UV filter.
References Mizdrak, J., et al.: Tetrahedron, 63, 4990 (2007); Taylor, L. M., et al.: Exp. Eye Res., 75, 165 (2002)

Formula: C₈H₈ClNO

Color and Shape: Neat

Molecular weight: 169.61

Ref: TR-A628050