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CAS 6469-93-8

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Chlorprothixene hydrochloride

Description:
Chlorprothixene hydrochloride is an antipsychotic medication primarily used in the treatment of schizophrenia and other psychotic disorders. It belongs to the thioxanthene class of neuroleptics and exhibits both antipsychotic and sedative properties. The compound functions as a dopamine antagonist, primarily targeting D2 receptors in the brain, which helps to alleviate symptoms of psychosis. Chlorprothixene hydrochloride is typically administered in its hydrochloride salt form, enhancing its solubility and bioavailability. The substance is characterized by its relatively low lipophilicity, which influences its pharmacokinetics and distribution in the body. Common side effects may include sedation, weight gain, and extrapyramidal symptoms, similar to other antipsychotic medications. It is important to monitor patients for these effects during treatment. As with any medication, the use of chlorprothixene hydrochloride should be guided by a healthcare professional, considering individual patient needs and potential drug interactions.
Formula:C18H19Cl2NS
InChI:InChI=1/C18H18ClNS.ClH/c1-20(2)11-5-7-14-15-6-3-4-8-17(15)21-18-10-9-13(19)12-16(14)18;/h3-4,6-10,12H,5,11H2,1-2H3;1H
InChI key:InChIKey=YWKRLOSRDGPEJR-KIUKIJHYSA-N
SMILES:C(\CCN(C)C)=C/1\C=2C(SC=3C1=CC=CC3)=CC=C(Cl)C2.Cl
Synonyms:
  • (3Z)-3-(2-chloro-9H-thioxanthen-9-ylidene)-N,N-dimethylpropan-1-amine hydrochloride
  • (Z)-2-Chloro-9-(3-dimethylaminopropylidene)thioxanthene hydrochloride
  • (Z)-Chlorprothixene hydrochloride
  • 1-Propanamine, 3-(2-chloro-9H-thioxanthen-9-ylidene)-N,N-dimethyl-, hydrochloride (1:1), (3Z)-
  • 1-Propanamine, 3-(2-chloro-9H-thioxanthen-9-ylidene)-N,N-dimethyl-, hydrochloride, (3Z)-
  • 1-Propanamine, 3-(2-chloro-9H-thioxanthen-9-ylidene)-N,N-dimethyl-, hydrochloride, (Z)-
  • 1-Propanamine, 3-(2-chloro-9H-thioxanthen-9-ylidene)-N,N-dimethyl-, hydrochloride, (Z)- (9CI)
  • 3-(2-chloro-9H-thioxanthen-9-ylidene)-N,N-dimethylpropan-1-amine hydrochloride
  • 9H-Thioxanthene, 1-propanamine deriv.
  • Chlorprothixene HCl
  • See more synonyms
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