CAS 64701-11-7

(3R,4R,5R,6R)-6-[[(8R,9S,10S,13S,14S,17R)-17-ethynyl-13-methyl-3-oxo-1,2,6,7,8,9,10,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-17-yl]oxy]-3,4,5-trihydroxy-tetrahydropyran-2-carboxylic acid

Description:

The chemical substance with the name "(3R,4R,5R,6R)-6-[[(8R,9S,10S,13S,14S,17R)-17-ethynyl-13-methyl-3-oxo-1,2,6,7,8,9,10,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-17-yl]oxy]-3,4,5-trihydroxy-tetrahydropyran-2-carboxylic acid" and CAS number "64701-11-7" is a complex organic molecule characterized by its multi-ring structure and multiple functional groups. It features a tetrahydropyran ring with three hydroxyl groups, indicating its potential as a polyol. The presence of an ethynyl group suggests reactivity that could be exploited in synthetic applications. Its stereochemistry, denoted by the (R) and (S) configurations, indicates specific spatial arrangements that may influence its biological activity and interactions. This compound is likely to exhibit significant pharmacological properties, potentially acting as a steroid or steroid-like molecule due to its structural similarities to steroid frameworks. The intricate arrangement of carbon atoms and functional groups suggests that it may participate in various chemical reactions, making it of interest in medicinal chemistry and drug development.

Formula: C₂₆H₃₄O₈

InChI: InChI=1/C26H34O8/c1-3-26(34-24-21(30)19(28)20(29)22(33-24)23(31)32)11-9-18-17-6-4-13-12-14(27)5-7-15(13)16(17)8-10-25(18,26)2/h1,12,15-22,24,28-30H,4-11H2,2H3,(H,31,32)/t15-,16-,17-,18+,19-,20-,21-,22?,24-,25+,26+/m1/s1

Norethindrone-17-O-β-D-glucuronide

CAS: 64701-11-7

Norethindrone-17-O-β-D-glucuronide

Purity: >95%

Molecular weight: 474.54g/mol

Ref: 54-BICL4177

Norethindrone b-D-glucuronide

CAS: 64701-11-7

Ref: 7W-GC8232

Norethindrone β-D-Glucuronide

CAS: 64701-11-7

Applications A metabolite of Norethindrone (N676000).
References Layne, D.S., et al.: Biochem. Pharmacol., 12, 905 (1963),

Formula: C₂₆H₃₄O₈

Color and Shape: Neat

Molecular weight: 474.54

Ref: TR-N676005

Norethindrone b-D-glucuronide

CAS: 64701-11-7

Norethindrone b-D-glucuronide is a synthetic steroid that has been modified to include a sugar group. This modification increases the solubility of the compound, which is necessary for its use as a progestogen in oral contraceptives. Norethindrone b-D-glucuronide is an orally active contraceptive that contains two sugar molecules that are attached to the hormone norethindrone. One sugar molecule is linked to the C2 carbon and the other is linked to the C3 carbon of norethindrone, forming a glucuronide ester. The glucuronide esters are more soluble than unconjugated norethindrone and this increased solubility allows for better absorption through mucous membranes.

Formula: C₂₆H₃₄O₈

Purity: Min. 95%

Molecular weight: 474.54 g/mol

Ref: 3D-MN16823