CAS 64709-57-5

N-(2-Chloroacetyl)-L-tryptophan

Description:

N-(2-Chloroacetyl)-L-tryptophan is an amino acid derivative characterized by the presence of a chloroacetyl group attached to the nitrogen of the tryptophan side chain. This compound features a tryptophan backbone, which is an essential amino acid known for its role in protein synthesis and as a precursor to serotonin. The chloroacetyl modification introduces a reactive electrophilic site, making it useful in various chemical reactions, including peptide synthesis and drug development. The presence of the chlorine atom enhances the compound's reactivity, potentially allowing for further functionalization. N-(2-Chloroacetyl)-L-tryptophan is typically utilized in biochemical research and pharmaceutical applications, particularly in the study of protein interactions and the development of novel therapeutic agents. Its solubility and stability in biological systems can vary, depending on the pH and the presence of other ions or molecules. As with many chemical substances, proper handling and safety precautions are essential due to its reactive nature.

Formula: C₁₃H₁₃ClN₂O₃

InChI: InChI=1S/C13H13ClN2O3/c14-6-12(17)16-11(13(18)19)5-8-7-15-10-4-2-1-3-9(8)10/h1-4,7,11,15H,5-6H2,(H,16,17)(H,18,19)/t11-/m0/s1

InChI key: InChIKey=PGTJUXHMJYBSBW-NSHDSACASA-N

SMILES: C([C@H](NC(CCl)=O)C(O)=O)C=1C=2C(NC1)=CC=CC2

Synonyms:

• (2R)-2-[(chloroacetyl)amino]-3-(1H-indol-3-yl)propanoate
• (2S)-2-[(chloroacetyl)amino]-3-(1H-indol-3-yl)propanoate
• <span class="text-smallcaps">L</span>-Tryptophan, N-(2-chloroacetyl)-
• <span class="text-smallcaps">L</span>-Tryptophan, N-(chloroacetyl)-
• Chloroac-Trp-OH
• Chloroacetyl-L-tryptophan
• N-(2-Chloroacetyl)-<span class="text-smallcaps">L</span>-tryptophan
• N-(chloroacetyl)tryptophan
• N-Chloroacetyl-<span class="text-smallcaps">L</span>-tryptophan
• NSC 523827
• Tryptophan, N-(chloroacetyl)-
• L-Tryptophan, N-(2-chloroacetyl)-
• N-(2-Chloroacetyl)-L-tryptophan
• N-Chloroacetyl-L-tryptophan

Chloroac-Trp-OH

CAS: 64709-57-5

Bachem ID: 4000756.

Formula: C₁₃H₁₃ClN₂O₃

Purity: > 99%

Color and Shape: White

Molecular weight: 280.71

Ref: 01-4000756

(S)-2-(2-Chloroacetamido)-3-(1H-indol-3-yl)propanoic acid

CAS: 64709-57-5

Formula: C₁₃H₁₃ClN₂O₃

Molecular weight: 280.7069

Ref: IN-DA003OT8

N-Chloroacetyl-L-tryptophan

CAS: 64709-57-5

N-Chloroacetyl-L-tryptophan is a synthetic biomimetic that inhibits the chloride channel in the intestine. It has been shown to inhibit the replication of a number of viruses, including HIV and influenza virus. N-Chloroacetyl-L-tryptophan has also been shown to have an inhibitory effect on intestinal sodium taurocholate, which is involved in fatty acid metabolism. This compound is a cyclic peptide with a lactam structure that contains a trifluoromethyl group. The kinetic data for this compound was obtained by measuring the rate of hydrolysis of L-tryptophan by pepsin at pH 2.5 and 37°C.

Formula: C₁₃H₁₂ClN₂O₃

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 280.7 g/mol

Ref: 3D-FC65984

Chloroacetyltryptophan

CAS: 64709-57-5

Chloroacetyltryptophan is a bioactive chemical substance.

Formula: C₁₃H₁₃ClN₂O₃

Purity: 98%

Color and Shape: Solid

Molecular weight: 280.71

Ref: TM-T20542