CAS 64744-50-9

2-Azaspiro[4.5]decan-3-one

Description:

2-Azaspiro[4.5]decan-3-one, identified by its CAS number 64744-50-9, is a bicyclic compound featuring a spiro structure that incorporates a nitrogen atom within its framework. This compound is characterized by its unique spirocyclic arrangement, which contributes to its potential biological activity and chemical reactivity. The presence of the carbonyl group (ketone) at the 3-position enhances its reactivity, making it a valuable intermediate in organic synthesis. Typically, such compounds exhibit moderate to high polarity due to the presence of functional groups, which can influence their solubility in various solvents. Additionally, the nitrogen atom in the structure may impart basic properties, allowing for interactions with acids and other electrophiles. 2-Azaspiro[4.5]decan-3-one may also exhibit interesting pharmacological properties, making it a subject of interest in medicinal chemistry. Overall, its unique structural features and functional groups make it a compound of interest for further research and application in various chemical and pharmaceutical contexts.

Formula: C₉H₁₅NO

InChI: InChI=1S/C9H15NO/c11-8-6-9(7-10-8)4-2-1-3-5-9/h1-7H2,(H,10,11)

InChI key: InChIKey=JAWPQJDOQPSNIQ-UHFFFAOYSA-N

SMILES: O=C1CC2(CN1)CCCCC2

Synonyms:

• 2-Azaspiro[4.5]decan-3-one
• 3,3-Pentamethylene-4-butyrolactam
• Gabapentin-lactams
• Gabapentin-lactam

4,4-Pentamethylene-2-pyrrolidone

CAS: 64744-50-9

Formula: C₉H₁₅NO

Purity: >98.0%(GC)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 153.23

Ref: 3B-P1695

GABAPENTIN IMPURITY A CRS

CAS: 64744-50-9

GABAPENTIN IMPURITY A CRS

Formula: C₉H₁₅NO

Molecular weight: 153.2215

Ref: 41-Y0001281

Gabapentin Related Compound A (2-Azaspiro[4.5]decan-3-one)

CAS: 64744-50-9

Lactams not elsewhere specified or included

Formula: C₉H₁₅NO

Color and Shape: Off-White Powder

Molecular weight: 153.11536

Ref: 45-1287325

2-Azaspiro[4.5]decan-3-one

CAS: 64744-50-9

Formula: C₉H₁₅NO

Purity: 95%

Color and Shape: Solid

Molecular weight: 153.2215

Ref: IN-DA003KGU

4,4-Pentamethylene-2-pyrrolidinone

CAS: 64744-50-9

4,4-Pentamethylene-2-pyrrolidinone

Formula: C₉H₁₅NO

Purity: 98%

Color and Shape: white solid

Molecular weight: 153.22g/mol

Ref: 54-OR350325

Gabapentin EP Impurity A (Gabapentin USP Related Compound A)

CAS: 64744-50-9

Formula: C₉H₁₅NO

Color and Shape: White To Off-White Solid

Molecular weight: 153.23

Ref: 4Z-G-105

Gabapentin-lactam

CAS: 64744-50-9

Formula: C₉H₁₅NO

Color and Shape: Neat

Molecular weight: 153.22

Ref: 04-C13991550

2-Azaspiro[4.5]decan-3-one (3,3-Pentamethylene-4-butyrolactam)

CAS: 64744-50-9

Color and Shape: Neat

Ref: 86-MM0684.01

Gabapentin-lactam 100 µg/mL in Acetonitrile

CAS: 64744-50-9

Formula: C₉H₁₅NO

Color and Shape: Single Solution

Molecular weight: 153.22

Ref: 04-A13991550AL-100

Gabapentin EP Impurity A

CAS: 64744-50-9

Formula: C₉H₁₅NO

Molecular weight: 153.22

Ref: ST-EA-CP-G3001

Gabapentin Lactam-d6

Controlled Product

CAS: 64744-50-9

Applications Gabapentin Lactam-d6, is the labeled analogue of Gabapentin Lactam (G117275), that reduces protein aggregates and improves motor performance in a transgenic mouse model of Huntington’s disease. It opens mitochondrial ATP-dependent potassium channels.
References Zucker, B.,et al.: Naunyn Schmiedebergs Arch. Pharmacol., 370, 131 (2004)

Formula: C₉H₉D₆NO

Color and Shape: Off White Solid

Molecular weight: 159.26

Ref: TR-G117277

Gabapentin Related Compound A

Controlled Product

CAS: 64744-50-9

Impurity Gabapentin EP Impurity A; Gabapentin USP Related Compound A
Applications Gabapentin Lactam (Gabapentin EP Impurity A; Gabapentin USP Related Compound A) reduces protein aggregates and improves motor performance in a transgenic mouse model of Huntington’s disease. It opens mitochondrial ATP-dependent potassium channels.
References Zucker, B.,et al.: Naunyn Schmiedebergs Arch. Pharmacol., 370, 131 (2004)

Formula: C₉H₁₅NO

Color and Shape: White

Molecular weight: 153.22

Ref: TR-G117275

2-Aza-spiro[4.5]decan-3-one

CAS: 64744-50-9

Formula: C₉H₁₅NO

Purity: 95%

Color and Shape: Solid

Molecular weight: 153.225

Ref: 10-F070856

Gabapentin related compound A

CAS: 64744-50-9

Gabapentin related compound A is a gamma-aminobutyric acid analogue that has been shown to reduce diabetic neuropathy in vivo. It binds to the GABA-B receptor, which is a ligand-gated chloride channel. Gabapentin related compound A produces a rapid increase in chloride ion conductance and hyperpolarization of neurons, leading to its neuroprotective effect. The chemical stability of this drug has been investigated by hydrolysis with hydrochloric acid under various conditions. The reaction mechanism for gabapentin related compound A is similar to that of gabapentin, but it has an analog structure that confers additional stability.

Formula: C₉H₁₅NO

Purity: Min. 95%

Color and Shape: White To Off-White Solid

Molecular weight: 153.22 g/mol

Ref: 3D-FG23633