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CAS 647839-20-1

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Uridine, 2'-O-(2-methoxyethyl)-2-thio-

Description:
Uridine, 2'-O-(2-methoxyethyl)-2-thio- is a modified nucleoside that features a uridine base with specific chemical alterations. The "2'-O-(2-methoxyethyl)" modification indicates that a methoxyethyl group is attached to the 2' position of the ribose sugar, enhancing its stability and potentially influencing its biological activity. The "2-thio" designation signifies that a sulfur atom replaces the oxygen atom at the 2-position of the ribose, which can affect the nucleoside's reactivity and interactions with enzymes. This compound is of interest in biochemical research and therapeutic applications, particularly in the context of nucleic acid chemistry, where modifications can enhance the pharmacological properties of nucleosides. Its unique structure may improve cellular uptake and resistance to nucleases, making it a candidate for use in drug development or as a research tool in molecular biology. As with many modified nucleosides, its characteristics, including solubility, stability, and biological activity, are influenced by the specific modifications present.
Formula:C12H18N2O6S
Synonyms:
  • 3’-O-(2-Methoxyethyl)-2-thiouridine
  • 3'-O-(2-Methoxyethyl)-2-thiouridine
  • Uridine, 2'-O-(2-methoxyethyl)-2-thio- (9CI)
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