CAS 648449-76-7

5-[(2,2-Difluoro-1,3-benzodioxol-5-yl)methylene]-2,4-thiazolidinedione

Description:

5-[(2,2-Difluoro-1,3-benzodioxol-5-yl)methylene]-2,4-thiazolidinedione, with CAS number 648449-76-7, is a synthetic organic compound that belongs to the class of thiazolidinediones, which are known for their role in pharmacology, particularly in the treatment of diabetes. This compound features a thiazolidinedione core, characterized by a five-membered ring containing sulfur and nitrogen, which is fused to a benzodioxole moiety that contributes to its unique properties. The presence of difluoro substituents enhances its lipophilicity and may influence its biological activity. The compound is typically studied for its potential effects on glucose metabolism and insulin sensitivity, making it of interest in diabetes research. Its structural complexity suggests that it may exhibit specific interactions with biological targets, potentially leading to therapeutic applications. As with many synthetic compounds, its stability, solubility, and reactivity can vary based on environmental conditions and the presence of other substances. Safety and handling precautions should be observed due to its chemical nature.

Formula: C₁₁H₅F₂NO₄S

InChI: InChI=1S/C11H5F2NO4S/c12-11(13)17-6-2-1-5(3-7(6)18-11)4-8-9(15)14-10(16)19-8/h1-4H,(H,14,15,16)

InChI key: InChIKey=SRLVNYDXMUGOFI-UHFFFAOYSA-N

SMILES: FC1(F)OC=2C(=CC(C=C3SC(=O)NC3=O)=CC2)O1

Synonyms:

• 5-[(2,2-Difluoro-1,3-benzodioxol-5-yl)methylene]thiazolidine-2,4-dione
• 2,4-Thiazolidinedione, 5-[(2,2-difluoro-1,3-benzodioxol-5-yl)methylene]-
• AS 604850
• 5-[(2,2-Difluoro-1,3-benzodioxol-5-yl)methylene]-2,4-thiazolidinedione

AS-604850

CAS: 648449-76-7

AS-604850

Purity: ≥98%

Molecular weight: 285.22g/mol

Ref: 54-BUP11381

AS-604850

CAS: 648449-76-7

AS-604850: ATP-competitive PI3Kγ inhibitor, IC50 250 nM, 18x > PI3Kα, 80x > PI3Kδ/β.

Formula: C₁₁H₅F₂NO₄S

Purity: 99.65%

Color and Shape: Solid

Molecular weight: 285.22

Ref: TM-T6394

AS 604850

CAS: 648449-76-7

Inhibitor of PI3K? kinase

Formula: C₁₁H₅F₂NO₄S

Purity: Min. 95%

Molecular weight: 285.22 g/mol

Ref: 3D-FA100638