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CAS 64872-76-0

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Butoconazole

Description:
Butoconazole is an antifungal agent primarily used in the treatment of various fungal infections, particularly those affecting the skin and mucous membranes. It belongs to the class of imidazole derivatives, which function by inhibiting the synthesis of ergosterol, an essential component of fungal cell membranes, thereby disrupting their integrity and leading to cell death. Butoconazole is typically formulated as a topical cream or solution, making it suitable for localized treatment. It exhibits a broad spectrum of activity against dermatophytes and yeast, including Candida species. The substance is characterized by its relatively low toxicity in humans when used as directed, although some individuals may experience localized irritation or allergic reactions. Its pharmacokinetics indicate limited systemic absorption when applied topically, which contributes to its safety profile. As with any antifungal treatment, it is essential to follow appropriate guidelines for use to ensure efficacy and minimize the risk of resistance development.
Formula:C19H17Cl3N2S
InChI:InChI=1S/C19H17Cl3N2S/c20-15-7-4-14(5-8-15)6-9-16(12-24-11-10-23-13-24)25-19-17(21)2-1-3-18(19)22/h1-5,7-8,10-11,13,16H,6,9,12H2
InChI key:InChIKey=SWLMUYACZKCSHZ-UHFFFAOYSA-N
SMILES:C(SC1=C(Cl)C=CC=C1Cl)(CN2C=CN=C2)CCC3=CC=C(Cl)C=C3
Synonyms:
  • (+-)-1-[4-(4-Chlorophenyl)-2-[(2,6-dichlorophenyl)thio]butyl]-1H-imidazole
  • 1-[2-(2,6-Dichlorophenylthio)-4-(4-chlorophenyl)-n-butyl]imidazole
  • 1-{4-(4-Chlorophenyl)-2-[(2,6-dichlorophenyl)sulfanyl]butyl}-1H-imidazole
  • 1H-imidazole, 1-[4-(4-chlorophenyl)-2-[(2,6-dichlorophenyl)thio]butyl]-
  • 64872-76-0
  • Butaconazole
  • Gynomyk
  • Butoconazole
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