CAS 648903-57-5

2-[[7-(3,4-Dimethoxyphenyl)imidazo[1,2-c]pyrimidin-5-yl]amino]-3-pyridinecarboxamide hydrochloride (1:2)

Description:

2-[[7-(3,4-Dimethoxyphenyl)imidazo[1,2-c]pyrimidin-5-yl]amino]-3-pyridinecarboxamide hydrochloride is a chemical compound characterized by its complex structure, which includes an imidazo[1,2-c]pyrimidine core and a pyridinecarboxamide moiety. This compound is typically a white to off-white solid and is soluble in polar solvents, which is common for many hydrochloride salts. The presence of multiple functional groups, including amine and carboxamide, suggests potential for hydrogen bonding and interactions with biological targets, making it of interest in medicinal chemistry. Its specific arrangement of methoxy groups on the phenyl ring may influence its pharmacological properties, such as bioavailability and receptor binding affinity. The compound's CAS number, 648903-57-5, allows for precise identification in chemical databases, facilitating research and development in various applications, particularly in drug discovery. Overall, this compound exemplifies the complexity and diversity of modern synthetic organic chemistry, with potential implications in therapeutic contexts.

Formula: C₂₀H₁₈N₆O₃·2ClH

InChI: InChI=1S/C20H18N6O3.2ClH/c1-28-15-6-5-12(10-16(15)29-2)14-11-17-22-8-9-26(17)20(24-14)25-19-13(18(21)27)4-3-7-23-19;;/h3-11H,1-2H3,(H2,21,27)(H,23,24,25);2*1H

InChI key: InChIKey=SPMFEULFGGPQLN-UHFFFAOYSA-N

SMILES: N(C=1N2C(C=C(N1)C3=CC(OC)=C(OC)C=C3)=NC=C2)C4=C(C(N)=O)C=CC=N4.Cl

Synonyms:

• BAY 61-3606 dihydrochloride
• 3-Pyridinecarboxamide, 2-[[7-(3,4-dimethoxyphenyl)imidazo[1,2-c]pyrimidin-5-yl]amino]-, hydrochloride (1:2)
• 2-[[7-(3,4-Dimethoxyphenyl)imidazo[1,2-c]pyrimidin-5-yl]amino]-3-pyridinecarboxamide hydrochloride (1:2)
• 3-Pyridinecarboxamide, 2-[[7-(3,4-dimethoxyphenyl)imidazo[1,2-c]pyrimidin-5-yl]amino]-, dihydrochloride

BAY 61-3606 dihydrochloride

CAS: 648903-57-5

BAY 61-3606 dihydrochloride

Purity: ≥95%

Molecular weight: 463.32g/mol

Ref: 54-BUP06994

BAY 61-3606 dihydrochloride

CAS: 648903-57-5

BAY 61-3606 dihydrochloride (BAY 61-3606) is a potent and selective inhibitor of Syk kinase (Ki = 7.5 nM).

Formula: C₂₀H₁₈N₆O₃·2HCl

Purity: 99.46%

Color and Shape: Solid

Molecular weight: 463.32

Ref: TM-T6776

BAY 61-3606 dihydrochloride

CAS: 648903-57-5

BAY 61-3606 dihydrochloride is a potent, selective inhibitor of phosphoinositide 3-kinase (PI3K) signaling, which is a synthetic chemical compound. It primarily inhibits the PI3K isoforms, particularly PI3Kβ and PI3Kδ, contributing to its utility in probing kinase-related pathways. Its mode of action involves competitive inhibition of the ATP-binding site of these kinases, thereby disrupting downstream signaling pathways critical for cell proliferation and survival.

Formula: C₂₀H₂₀Cl₂N₆O₃

Purity: Min. 95%

Molecular weight: 463.32 g/mol

Ref: 3D-YAB90357