CAS 64936-82-9

3-Sulfoglycolithocholic acid disodium salt

Description:

3-Sulfoglycolithocholic acid disodium salt is a bile acid derivative characterized by its sulfonate group, which enhances its solubility in aqueous environments. This compound is a disodium salt, indicating the presence of two sodium ions that balance the negative charge from the sulfonate group. It is typically used in biochemical research, particularly in studies involving bile acids and their role in lipid metabolism and absorption. The presence of the sulfonate group also suggests potential applications in drug formulation and delivery systems, as it may improve the compound's bioavailability. Additionally, 3-sulfoglycolithocholic acid disodium salt can interact with various biological membranes and proteins, making it a valuable tool for investigating membrane dynamics and transport mechanisms. Its structural features contribute to its amphipathic nature, allowing it to interact with both hydrophilic and hydrophobic environments. Overall, this compound serves as an important model for understanding the physiological roles of bile acids and their derivatives in biological systems.

Formula: C₂₆H₄₃NO₇S·2Na

InChI: InChI=1S/C26H43NO7S.2Na/c1-16(4-9-23(28)27-15-24(29)30)20-7-8-21-19-6-5-17-14-18(34-35(31,32)33)10-12-25(17,2)22(19)11-13-26(20,21)3;;/h16-22H,4-15H2,1-3H3,(H,27,28)(H,29,30)(H,31,32,33);;/t16-,17-,18-,19+,20-,21+,22+,25+,26-;;/m1../s1

InChI key: InChIKey=BSGXDGBJYOSJML-DJOVSRRHSA-N

SMILES: C[C@@]12[C@]([C@]3([C@@]([C@]4(C)[C@](CC3)(C[C@H](OS(=O)(=O)O)CC4)[H])(CC1)[H])[H])(CC[C@@]2([C@@H](CCC(NCC(O)=O)=O)C)[H])[H].[Na]

Synonyms:

• Glycine, N-[(3α,5β)-24-oxo-3-(sulfooxy)cholan-24-yl]-, disodium salt
• Glycine, N-[(3α,5β)-24-oxo-3-(sulfooxy)cholan-24-yl]-, sodium salt (1:2)
• 3-Sulfoglycolithocholic acid disodium salt

Glycolithocholic acid 3-sulfate (disodium)

CAS: 64936-82-9

Glycolithocholic acid 3-sulfate (disodium)

Purity: 98%

Molecular weight: 557.65g/mol

Ref: 54-OR1075735

3-Sulfoglycolithocholic Acid Disodium Salt-d5

CAS: 64936-82-9

Formula: C₂₆H₃₆D₅NO₇S·2Na

Molecular weight: 516.71 2*22.99

Ref: 4Z-L-1824

3-Sulfoglycolithocholic Acid Disodium Salt

CAS: 64936-82-9

Formula: C₂₆H₄₁NO₇S·2Na

Molecular weight: 511.68 2*22.99

Ref: 4Z-L-1823

3-Sulfoglycolithocholic Acid Disodium Salt

Controlled Product

CAS: 64936-82-9

Stability Hygroscopic
Applications 3-Sulfoglycolithocholic Acid Disodium Salt is a derivative of Lithocholic acid (L469180). Lithocholic acid (LCA) is a putative tumor promoter,that is shown to be able to inhibit mammalian DNA polymerase β.
References Ogawa, A., et al.: Jap. J. Canc. Res., 89, 1154 (1998)

Formula: C₂₆H₄₁NO₇S·2Na

Color and Shape: Neat

Molecular weight: 557.65

Ref: TR-S689115

3-Sulfoglycolithocholic Acid Disodium Salt-d5

Controlled Product

CAS: 64936-82-9

Formula: C₂₆D₅H₃₆NNa₂O₇S

Color and Shape: Neat

Molecular weight: 562.682

Ref: TR-S689117

3-Sulfoglycolithocholic acid disodium

CAS: 64936-82-9

3-Sulfoglycolithocholic acid disodium is a potential biomarker for inflammatory bowel disease. It is also used as an analytical method to measure bile acids in the blood. 3-Sulfoglycolithocholic acid disodium has been shown to be a strong indicator of liver inflammation and hepatitis. This compound can also be used as a diagnostic tool for infectious diseases, such as HIV and hepatitis C, by measuring serum bile acids levels. The level of this molecule can be measured in the blood and urine of patients with bowel disease, such as ulcerative colitis or Crohn's disease. 3-Sulfoglycolithocholic acid disodium can also be used to diagnose atrial fibrillation.

Formula: C₂₆H₄₃NO₇S•Na₂

Purity: Min. 95%

Molecular weight: 559.67 g/mol

Ref: 3D-FS167272

Glycolithocholic acid 3-sulfate disodium

CAS: 64936-82-9

Glycolithocholic acid 3-sulfate (disodium) demonstrates inhibitory effects on in vitro HIV-1 replication and has potential applications in HIV infection and

Formula: C₂₆H₄₁NNa₂O₇S

Color and Shape: Solid

Molecular weight: 557.65

Ref: TM-T78551