CAS 64936-83-0

taurolithocholic acid 3-sulfate*disodium

Description:

Taurolithocholic acid 3-sulfate disodium, with the CAS number 64936-83-0, is a bile acid derivative that plays a role in the metabolism of lipids and the absorption of fats in the digestive system. This compound is characterized by its sulfate group, which enhances its solubility in water compared to its parent bile acids. It is typically found in the form of a disodium salt, which contributes to its ionic nature and affects its interaction with biological membranes. The presence of the taurine moiety in its structure suggests that it may have specific biological functions, including potential roles in signaling pathways and modulation of gut microbiota. Additionally, taurolithocholic acid 3-sulfate disodium is of interest in research related to liver function and cholesterol metabolism. Its properties, such as solubility, stability, and biological activity, make it a subject of study in pharmacology and biochemistry, particularly in understanding its implications in health and disease.

Formula: C₂₆H₄₃NNa₂O₈S₂

Synonyms:

• disodium:2-[[(4R)-4-[(3R,5R,8R,9S,10S,13R,14S,17R)-10,13-dimethyl-3-sulfonatooxy-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoyl]amino]ethanesulfonate
• Taurolithocholic Acid Sulfate Disodium Salt
• 3ALPHA-HYDROXY-5BETA-CHOLAN-24-OIC ACID N-[2-SULFOETHYL]AMIDE 3-SULFATE DISODIUM SALT
• TAUROLITHOCHOLIC ACID 3-SULFATE DISODIUM SALT
• 3α-Hydroxy-5β-cholan-24-oic acid n-(2-sulfoethyl)amide 3-sulfate disodium salt
• 3α-hydroxy-5β-cholan-24-oic acid n-(2-sulfoethyl)amide 3-sulfate
• TAUROLITHOCHOLIC ACID 3-SULFATE*DISO
• Taurolithocholic Acid 3-sulfate (sodium salt)
• taurolithocholic acid 3-sulfate*disodium

3α-HYDROXY-5β-CHOLAN-24-OIC ACID N-[2-SULFOETHYL]AMIDE 3-SULFATE DISODIUM SALT

CAS: 64936-83-0

Formula: C₂₆H₄₃NNa₂O₈S₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 607.7311

Ref: IN-DA00EF13

Taurolithocholic Acid 3-sulfate (sodium salt)

CAS: 64936-83-0

TLCA3S, a taurolithocholic acid metabolite, is used for studying bile acid transport and inducing pancreatitis in mice.

Formula: C₂₆H₄₃NNa₂O₈S₂

Color and Shape: Solid

Molecular weight: 607.73

Ref: TM-T37771

Taurolithocholic acid 3-sulfate (disodium)

CAS: 64936-83-0

Molecular weight: 607.73

Ref: 10-F987387

Taurolithocholic Acid Sulfate Disodium Salt

Controlled Product

CAS: 64936-83-0

Stability Hygroscopic
Applications Disodium salt of Taurolithocholic Acid Sulfate, a metabolite of bile acids. Sulfation is a major metabolic pathway involved in the elimination and detoxification of bile acids (BAs).
References Kawamata, Y., et al.: J. Biol. Chem., 278, 9435 (2003); Alnouti, Y., et al.: Toxicol. Sci., 108, 225 (2009); Griffiths, W., et al.: J. Lipid Res., 51, 23 (2010); Huang, J., et al.: Xenobiotica, 2010, 40, 184 (2010);

Formula: C₂₆H₄₃NO₈S₂·2Na

Color and Shape: Neat

Molecular weight: 607.73

Ref: TR-T009115

Taurolithocholic Acid-2,2,3,4,4-d5 Sulfate Disodium Salt

Controlled Product

CAS: 64936-83-0

Formula: C₂₆D₅H₃₈NNa₂O₈S₂

Color and Shape: Neat

Molecular weight: 612.762

Ref: TR-T009117

Taurolithocholic acid 3-sulfate disodium salt

CAS: 64936-83-0

Taurolithocholic acid 3-sulfate disodium salt (TLCA) is a bile acid that has been used to treat pancreatitis. This drug is a reactive agent that can be utilised by the pancreas and c. tinctoria. TLCA has been shown to inhibit reactive oxygen species and induce necrotic cell death, which may be due to its antioxidant effects. TLCA also inhibits proliferation of pancreatic cancer cells in vitro and can be used as a potential treatment for pancreatic cancer.

Formula: C₂₆H₄₃NO₈S₂Na₂

Purity: Min. 95%

Molecular weight: 607.73 g/mol

Ref: 3D-PCA93683