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CAS 64953-12-4

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Latamoxef sodium

Description:
Latamoxef sodium is a synthetic antibiotic belonging to the oxacephem class, which is structurally related to cephalosporins. It exhibits broad-spectrum antibacterial activity, particularly against Gram-positive and some Gram-negative bacteria. Latamoxef is notable for its stability against certain beta-lactamases, enzymes produced by bacteria that can inactivate many antibiotics. This characteristic enhances its effectiveness in treating infections caused by resistant strains. The compound is typically administered via injection and is used in various clinical settings, particularly for treating respiratory tract infections, skin infections, and other bacterial infections. Latamoxef sodium is also characterized by its solubility in water, which facilitates its use in intravenous formulations. Its pharmacokinetics involve rapid distribution in body tissues, and it is primarily excreted through the kidneys. As with any antibiotic, the potential for adverse effects exists, including allergic reactions and gastrointestinal disturbances. Overall, Latamoxef sodium represents an important option in the arsenal against bacterial infections, particularly in cases where resistance to other antibiotics is a concern.
Formula:C20H18N6Na2O9S
InChI:InChI=1/C20H20N6O9S.2Na/c1-25-19(22-23-24-25)36-8-10-7-35-18-20(34-2,17(33)26(18)13(10)16(31)32)21-14(28)12(15(29)30)9-3-5-11(27)6-4-9;;/h3-6,12,18,27H,7-8H2,1-2H3,(H,21,28)(H,29,30)(H,31,32);;/q;2*+1/p-2/t12?,18-,20+;;/m1../s1
InChI key:InChIKey=WXZMENVSIQCXRV-GDUWRUPCSA-N
SMILES:N(C([C@H](C(O)=O)C1=CC=C(O)C=C1)=O)[C@@]2(OC)[C@@]3(N(C2=O)C(C(O)=O)=C(CSC=4N(C)N=NN4)CO3)[H].[Na]
Synonyms:
  • 5-Oxa-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[(2R)-2-carboxy-2-(4-hydroxyphenyl)acetyl]amino]-7-methoxy-3-[[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-, sodium salt (1:2), (6R,7R)-
  • 5-Oxa-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[(2R)-carboxy(4-hydroxyphenyl)acetyl]amino]-7-methoxy-3-[[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-, disodium salt, (6R,7R)-
  • 6059S
  • Antibiotic 6059S
  • Disodium latamoxef
  • Festamoxin
  • Latamoxef sodium
  • Ly 12735
  • Ly 127935
  • Mixture Of Isomers
  • See more synonyms
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