CAS 64953-12-4

Latamoxef sodium

Description:

Latamoxef sodium is a synthetic antibiotic belonging to the oxacephem class, which is structurally related to cephalosporins. It exhibits broad-spectrum antibacterial activity, particularly against Gram-positive and some Gram-negative bacteria. Latamoxef is notable for its stability against certain beta-lactamases, enzymes produced by bacteria that can inactivate many antibiotics. This characteristic enhances its effectiveness in treating infections caused by resistant strains. The compound is typically administered via injection and is used in various clinical settings, particularly for treating respiratory tract infections, skin infections, and other bacterial infections. Latamoxef sodium is also characterized by its solubility in water, which facilitates its use in intravenous formulations. Its pharmacokinetics involve rapid distribution in body tissues, and it is primarily excreted through the kidneys. As with any antibiotic, the potential for adverse effects exists, including allergic reactions and gastrointestinal disturbances. Overall, Latamoxef sodium represents an important option in the arsenal against bacterial infections, particularly in cases where resistance to other antibiotics is a concern.

Formula: C₂₀H₁₈N₆Na₂O₉S

InChI: InChI=1/C20H20N6O9S.2Na/c1-25-19(22-23-24-25)36-8-10-7-35-18-20(34-2,17(33)26(18)13(10)16(31)32)21-14(28)12(15(29)30)9-3-5-11(27)6-4-9;;/h3-6,12,18,27H,7-8H2,1-2H3,(H,21,28)(H,29,30)(H,31,32);;/q;2*+1/p-2/t12?,18-,20+;;/m1../s1

InChI key: InChIKey=WXZMENVSIQCXRV-GDUWRUPCSA-N

SMILES: N(C([C@H](C(O)=O)C1=CC=C(O)C=C1)=O)[C@@]2(OC)[C@@]3(N(C2=O)C(C(O)=O)=C(CSC=4N(C)N=NN4)CO3)[H].[Na]

Synonyms:

• 5-Oxa-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[(2R)-2-carboxy-2-(4-hydroxyphenyl)acetyl]amino]-7-methoxy-3-[[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-, sodium salt (1:2), (6R,7R)-
• 5-Oxa-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[(2R)-carboxy(4-hydroxyphenyl)acetyl]amino]-7-methoxy-3-[[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-, disodium salt, (6R,7R)-
• 6059S
• Antibiotic 6059S
• Disodium latamoxef
• Festamoxin
• Latamoxef sodium
• Ly 12735
• Ly 127935
• Mixture Of Isomers
• Moxalactam Disodium
• Moxalactam Sodium
• S 6059
• Shiomarin
• Shionogi 6059S
• disodium (6R,7R)-7-{[carboxylato(4-hydroxyphenyl)acetyl]amino}-7-methoxy-3-{[(1-methyl-1H-tetrazol-5-yl)sulfanyl]methyl}-8-oxo-5-oxa-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
• disodium 7-{[carboxylato(4-hydroxyphenyl)acetyl]amino}-7-methoxy-3-{[(1-methyl-1H-tetrazol-5-yl)sulfanyl]methyl}-8-oxo-5-oxa-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
• moxalactamdisodium
• Latamoxef Disodium
• (6R,7R)-7-[2-Carboxy-2-(p-hydroxyphenyl)acetylamino]-7-methoxy-3-(1-methyl-1H-tetrazol-5-ylthiomethyl)-8-oxo-5-oxa-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid disodium salt
• disodiumlatamoxef
• 5-Oxa-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid, 7-((carboxy(4-hydroxyphenyl)acetyl)amino)-7-methoxy-3-(((1-methyl-1H-tetrazol-5-yl)thio)methyl)-8-oxo-, disodium salt
• Latamoxef sodiumr
• ly127935
• moxam
• 5-Oxa-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[(2R)-carboxy(4-hydroxyphenyl)acetyl]amino]-7-methoxy-3-[[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-, disodium salt, (6R,7R)- (9CI)
• Moxalactam Sodium Salt (Mixture of Diastereomers) (10mM in DMSO)
• antibiotic6059-s
• MOXALACTAM SODIUM SALT
• 5-oxa-1-azabicyclo(4.2.o)oct-2-ene-2-carboxylicacid,7-((carboxy(4-hydroxyphen
• (6R,7R)-7-[[(2R)-Carboxy(4-hydroxyphenyl)acetyl]aMino]-7-Methoxy-3-[[(1-Methyl-1H-tetrazol-5-yl)thio]Methyl]-8-oxo-5-oxa-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid DisodiuM Salt
• MoxalactaM SodiuM Salt (Mixture of diastereoMers)
• Moxalactam sodium, >=830 μg/mg
• Einecs 265-288-4
• Moxalactam Disodium (500 mg)
• Latamoxef sodium USP/EP/BP
• FestamoxinLy
• 5-Oxa-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylicacid,7-[[(2R)-2-carboxy-2-(4-hydroxyphenyl)acetyl]aMino]-7-Methoxy-3-[[(1-Methyl-1H-tetrazol-5-yl)thio]Methyl]-8-oxo-,sodiuM salt (1:2), (6R,7R)-
• moxalactam sodium salt, mixture of isomers
• HY-B1484
• disodium 7-[[carboxylato(4-hydroxyphenyl)acetyl]amino]-7-methoxy-3-[[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-5-oxa-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate

5-Oxa-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[(2R)-2-carboxy-2-(4-hydroxyphenyl)acetyl]amino]-7-methoxy-3-[[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-, sodium salt (1:2), (6R,7R)-

CAS: 64953-12-4

Formula: C₂₀H₁₈N₆Na₂O₉S

Purity: 85%

Color and Shape: Solid

Molecular weight: 564.4363

Ref: IN-DA003R88

Moxalactam Disodium

CAS: 64953-12-4

Moxalactam Disodium

Purity: ≥90%

Molecular weight: 564.44g/mol

Ref: 54-BUP18007

Moxalactam sodium salt

CAS: 64953-12-4

Formula: C₂₀H₁₈N₆Na₂O₉S

Purity: ≥ 830μg/mg

Color and Shape: White to light-yellow powder

Molecular weight: 564.44

Ref: 7W-GA5791

Sodium (6R,7R)-7-((R)-2-Carboxylato-2-(4-Hydroxyphenyl)Acetamido)-7-Methoxy-3-(((1-Methyl-1H-Tetrazol-5-Yl)Thio)Methyl)-8-Oxo-5-Oxa-1-Azabicyclo[4.2.0]Oct-2-Ene-2-Carboxylate

CAS: 64953-12-4

Sodium (6R,7R)-7-((R)-2-Carboxylato-2-(4-Hydroxyphenyl)Acetamido)-7-Methoxy-3-(((1-Methyl-1H-Tetrazol-5-Yl)Thio)Methyl)-8-Oxo-5-Oxa-1-Azabicyclo[4.2.0]Oct-2-Ene-2-Carboxylate

Purity: 85%

Molecular weight: 564.44g/mol

Ref: 54-OR1025382

Moxalactam Disodium

CAS: 64953-12-4

Moxalactam sodium salt (LY-127935) is an antibiotic compound more effective against Escherichia coli and Pseudomonas aeruginosathan cephalosporins.

Formula: C₂₀H₁₈N₆Na₂O₉S

Purity: 93.33%

Color and Shape: Solid

Molecular weight: 564.44

Ref: TM-T6179

Moxalactam Sodium Salt (Mixture of diastereomers)

CAS: 64953-12-4

Moxalactam Sodium Salt (Mixture of diastereomers) is an oxacephem antibiotic with action on bacterial cell wall synthesis and is used for treating infections caused by gram-negative bacteria like Escherichia coli and Pseudomonas aeruginosa

Formula: C₂₀H₁₈N₆Na₂O₉S

Purity: Min. 95 Area-%

Color and Shape: Powder

Molecular weight: 564.44 g/mol

Ref: 3D-AM26094

Moxalactam Sodium Salt (Mixture of Diastereomers)

Controlled Product

CAS: 64953-12-4

Stability Unstable in solution (DMSO or Methanol)
Applications Moxalactam Sodium is an oxacephem antibiotic. Moxalactam Sodium is more effective against Escherichia coli and Pseudomonas aeruginosa than cephalosporins.
References Yamamoto, K. et al.: Chemotherapy, 28, 1158 (1980); Toyonaga, Y. et al.: Jap. J. Antibiot., 34, 764 (1981); Nishimura, T. et al.: Jap. J. Antibiot., 34, 800 (1981):

Formula: C₂₀H₁₈N₆Na₂O₉S

Color and Shape: Neat

Molecular weight: 564.44

Ref: TR-M745600

Moxalactam Sodium Salt extrapure, 85%

CAS: 64953-12-4

Formula: C₂₀H₁₈N₆Na₂O₁₀S₂

Molecular weight: 564.44

Ref: SR-77810