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CAS 64967-16-4

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5-fluoro-1-(beta-D-ribofuranosyl)pyrimidin-2(1H)-one

Description:
5-Fluoro-1-(beta-D-ribofuranosyl)pyrimidin-2(1H)-one is a nucleoside analog characterized by its pyrimidine base structure, which includes a fluorine atom at the 5-position. This compound features a ribofuranosyl sugar moiety, contributing to its classification as a nucleoside. The presence of the fluorine atom can influence the compound's biological activity, potentially enhancing its stability and altering its interaction with nucleic acid targets. The ribofuranosyl component is essential for its incorporation into nucleic acids, making it relevant in the study of antiviral and anticancer agents. This substance is typically soluble in polar solvents, reflecting the hydrophilic nature of the ribose sugar. Its structural characteristics allow it to mimic natural nucleosides, which can be advantageous in therapeutic applications. The compound's CAS number, 64967-16-4, facilitates its identification in chemical databases and literature, aiding researchers in accessing relevant information regarding its synthesis, properties, and potential uses in medicinal chemistry.
Formula:C9H11FN2O5
InChI:InChI=1/C9H11FN2O5/c10-4-1-11-9(16)12(2-4)8-7(15)6(14)5(3-13)17-8/h1-2,5-8,13-15H,3H2/t5-,6-,7-,8-/m1/s1
SMILES:c1c(cn([C@H]2[C@@H]([C@@H]([C@@H](CO)O2)O)O)c(=O)n1)F
Synonyms:
  • 2(1H)-Pyrimidinone, 5-fluoro-1-.beta.-D-ribofuranosyl-
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Found 1 products.
  • 5-Fluoropyrimidin-2-One β-Ribofuranoside

    CAS:
    <p>5-Fluoropyrimidin-2-One beta-Ribofuranoside is a subunit of the enzyme cytidine deaminase. It interacts with a substrate binding site, which is located at the active site of cytidine deaminase. This molecule has been shown to stabilize the enzyme and increase its rate of reaction with the substrate. 5-Fluoropyrimidin-2-One beta-Ribofuranoside can also bind with a water molecule, which may be important for enzymatic activity.<br>5-Fluoropyrimidin-2-One beta-Ribofuranoside is homologous to other molecules that are involved in DNA synthesis, such as adenosine monophosphate (AMP), ribose, and uracil.</p>
    Formula:C9H11FN2O5
    Purity:Min. 95%
    Molecular weight:246.19 g/mol

    Ref: 3D-FF87642

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