CAS 649735-63-7: L-Alanine,(1R)-2-[[4-[(4-fluoro-2-methyl-1H-indol-5-yl)oxy]-5-methylpyrrolo[2,1-f][1,2,4]triazin-6-yl]oxy]-1-methylethylester

Description: L-Alanine, (1R)-2-[[4-[(4-fluoro-2-methyl-1H-indol-5-yl)oxy]-5-methylpyrrolo[2,1-f][1,2,4]triazin-6-yl]oxy]-1-methylethylester, identified by CAS number 649735-63-7, is a complex organic compound characterized by its structural components, which include an alanine moiety and a pyrrolo-triazine derivative. This compound features a chiral center, indicated by the (1R) configuration, which can influence its biological activity and interactions. The presence of a fluorinated indole and a pyrrolo[2,1-f][1,2,4]triazin moiety suggests potential pharmacological properties, possibly related to its role as a bioactive molecule. The ester functional group indicates that it may undergo hydrolysis in biological systems, potentially releasing L-alanine and other active fragments. Its solubility, stability, and reactivity would depend on the specific functional groups and their interactions with solvents and biological targets. Overall, this compound's unique structure may contribute to its utility in medicinal chemistry and drug development, warranting further investigation into its properties and applications.

Formula: C₂₂H₂₄FN₅O₄

InChI: InChI=1S/C22H24FN5O4/c1-11-7-15-16(27-11)5-6-17(19(15)23)32-21-20-13(3)18(8-28(20)26-10-25-21)30-9-12(2)31-22(29)14(4)24/h5-8,10,12,14,27H,9,24H2,1-4H3/t12-,14+/m1/s1

InChI key: InChIKey=LTEJRLHKIYCEOX-OCCSQVGLSA-N

SMILES: O=C(OC(C)COC1=CN2N=CN=C(OC=3C=CC=4NC(=CC4C3F)C)C2=C1C)C(N)C

Synonyms:

• (1R)-2-((4-((4-Fluoro-2-methyl-1H-indol-5-yl)oxy)-5-methylpyrrolo[2,1-f][1,2,4]triazin-6-yl)oxy)-1-methylethyl L-alanine ester
• <span class="text-smallcaps">L</span>-Alanine, (1R)-2-[[4-[(4-fluoro-2-methyl-1H-indol-5-yl)oxy]-5-methylpyrrolo[2,1-f][1,2,4]triazin-6-yl]oxy]-1-methylethyl ester
• Bms 582664
• Bms582664
• Brivanib alaninate

Unii-U2Y5ofn795

CAS: 649735-63-7

• Formula: C₂₂H₂₄FN₅O₄
• Purity: 98%
• Color and Shape: Solid
• Molecular weight: 441.4555

Brivanib (alaninate)

CAS: 649735-63-7

• Purity: 99.22%
• Molecular weight: 441.46g/mol

Brivanib alaninate

CAS: 649735-63-7

• Formula: C₂₂H₂₄FN₅O₄
• Purity: ≥ 95.0%
• Color and Shape: White to off-white powder
• Molecular weight: 441.46

Brivanib alaninate

CAS: 649735-63-7

VEGFR2 a tyrosine kinase receptor inhibitor; antineoplastic

• Formula: C₂₂H₂₄FN₅O₄
• Purity: Min. 95%
• Color and Shape: Powder
• Molecular weight: 441.18123

Brivanib (alaninate)

CAS: 649735-63-7

Brivanib Alaninate (BMS-582664) is an alaninate salt of a vascular endothelial growth factor receptor 2 …

• Formula: C₂₂H₂₄FN₅O₄
• Purity: 99.46% - 99.66%
• Color and Shape: Solid
• Molecular weight: 441.46

Brivanib Alaninate

CAS: 649735-63-7

Applications A novel prodrug of dual vascular endothelial growth factor receptor-2 and fibroblast growth factor …

• Formula: C₂₂H₂₄FN₅O₄
• Color and Shape: Neat
• Molecular weight: 441.455