CAS 65-31-6

(-)-Nicotine hydrogen (+)-tartrate

Description:

(-)-Nicotine hydrogen (+)-tartrate, with the CAS number 65-31-6, is a salt formed from the alkaloid nicotine and tartaric acid. This compound is characterized by its chiral nature, as it contains both the (-)-nicotine, which is the naturally occurring enantiomer, and the (+)-tartrate ion. It typically appears as a white crystalline solid and is soluble in water, which is a common property of many salts. The compound exhibits pharmacological activity, primarily due to the presence of nicotine, which acts as a stimulant affecting the central nervous system. Its applications are often found in research settings, particularly in studies related to nicotine's effects on neurotransmission and addiction. Additionally, the presence of the tartrate moiety can influence the compound's stability and solubility, making it relevant in the formulation of pharmaceuticals. Overall, (-)-Nicotine hydrogen (+)-tartrate serves as an important compound in both chemical research and potential therapeutic applications.

Formula: C₁₈H₂₆N₂O₁₂

InChI: InChI=1/C10H14N2.C4H6O6/c1-12-7-3-5-10(12)9-4-2-6-11-8-9;5-1(3(7)8)2(6)4(9)10/h2,4,6,8,10H,3,5,7H2,1H3;1-2,5-6H,(H,7,8)(H,9,10)/t10-;/m0./s1

InChI key: InChIKey=QLDPCHZQQIASHX-LDGFUSNJSA-N

SMILES: [C@@H]([C@H](C(O)=O)O)(C(O)=O)O.CN1[C@@H](CCC1)C=2C=CC=NC2

Synonyms:

• (-)-Nicotine ditartrate
• (-)-Nicotine hydrogen (+)-tartrate
• 3-(1-Methylpyrrolidin-2-Yl)Pyridine 2,3-Dihydroxybutanedioate (1:1)
• 3-[(2S)-1-methylpyrrolidin-2-yl]pyridine 2,3-dihydroxybutanedioate (salt)
• 3-[(2S)-1-methylpyrrolidin-2-yl]pyridine bis(2,3-dihydroxybutanedioate) (salt)
• NSC 97238
• Nicotine acid tartrate
• Nicotine bitartrate
• Nicotine tartrate
• Nicotine, tartrate (1:2)
• Np002
• Pyridine, 3-(1-methyl-2-pyrrolidinyl)-, (S)-, [R-(R*,R*)]-2,3-dihydroxybutanedioate (1:2)
• Pyridine, 3-[(2S)-1-methyl-2-pyrrolidinyl]-, (2R,3R)-2,3-dihydroxybutanedioate (1:2)
• S-(-)-Nicotine hydrogen-(+)-tartrate
• pyridine,3-(1-methyl-2-pyrrolidinyl)-,(s)-,(r-(r*,r*))-2,3-dihydroxybutanedi
• nicotinehydrogentartrate
• tartratedenicotine
• (S)-3-(1-METHYL-2-PYRROLIDINYL)PYRIDINE TARTRATE SALT
• (-)-NICOTINE TARTRATE SALT
• (-)-1-METHYL-2-[3-PYRIDYL]PYRROLIDINE DI-(+) TARTRATE SALT
• nicotineacidtartrate
• pyridine,3-(1-methyl-2-pyrrolidinyl)-,(s)-,(r-(r*,r*))-2,3-dihydroxybutane
• NICOTINE HYDROGEN-L-TARTRATE
• (-)-NICOTINE HYDROGEN TARTRATE SALT
• (-)-nicotinehydrogentartrate
• nikotinbitartrat
• (S)-3-(1-METHYL-2-PYRROLINDINYL)PYRIDINE TARTRATE SALT
• (S)-3-(1-METHYL-2-PYRROLIDINYL)PYRIDINE, DI-D-TARTRATE
• (S)-3-(1-METHYL-2-PYRROLINDINYL)PYRIDINE, DI-D-TARTRATE

Nicotine Bi-L-(+)-tartrate Dihydrate

CAS: 2624-48-8, 6019-06-3, 65-31-6

Formula: C₁₀H₁₄N₂·2C₄H₆O₆·2H₂O

Purity: >98.0%(HPLC)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 498.44

Ref: 3B-N0080

NICOTINE DITARTRATE CRS

CAS: 65-31-6

NICOTINE DITARTRATE CRS

Formula: C₁₈H₂₆N₂O₁₂

Molecular weight: 462.4052

Ref: 41-N0590200

(-)-Nicotine hydrogen tartrate salt

CAS: 65-31-6

Formula: C₁₀H₁₄N₂·2C₄H₆O₆(anhydrous)

Purity: (HPLC) 98.5 - 101.5 % (anhydrous basis)

Color and Shape: White to almost white powder

Molecular weight: 462.41 (anhydrous)

Ref: 7W-GL9693

Nicotine ditartrate

Controlled Product

CAS: 65-31-6

Formula: C₁₀H₁₄N₂C₄H₆O₆

Color and Shape: Neat

Molecular weight: 462.41

Ref: 04-C15520200

(-)-Nicotine Ditartrate

CAS: 65-31-6

Formula: C₁₀H₁₄N₂C₄H₆O₆

Molecular weight: 162.24 2*150.09

Ref: 4Z-N-0690

Nicotine ditartrate

CAS: 65-31-6

Natural alkaloid

Formula: C₁₀H₁₄N₂C₄H₆O₆

Purity: ≥ 95.0 % (HPLC)

Color and Shape: Powder

Molecular weight: 462.41

Ref: 5G-80224

(-)-Nicotine Ditartrate

CAS: 65-31-6

Applications (-)-Nicotine ditartrate is a potent agonist of AChR.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Rodriguez, J. et al.: Psychopharmacol., 231, 4455 (2014);

Formula: C₁₀H₁₄N₂·2C₄H₆O₆

Color and Shape: Off-White

Molecular weight: 462.41

Ref: TR-N424598

(-)-Nicotine ditartrate

CAS: 65-31-6

(-)-Nicotine ditartrate is a polymorphic form of nicotine. It is a hydrogen tartrate salt with the chemical formula C10H14N2O4·H2O. (-)-Nicotine ditartrate has been shown to improve locomotor activity and reduce cortisol concentration in mice. In addition, this compound has been shown to inhibit oxidative injury in mice by reducing reactive oxygen species production. (-)-Nicotine ditartrate is also able to inhibit glutamate release from nerve terminals, which may be due to its ability to stimulate nicotinic acetylcholine receptors (nAChRs). Further, it can induce apoptosis in cancer cells through activation of the MCL-1 protein and inhibition of cholinergic neurotransmission. This drug can also be used as an electrochemical impedance spectroscopy probe for the detection of reactive oxygen species.

Formula: C₁₀H₁₄N₂·2C₄H₆O₆

Purity: Min. 95%

Molecular weight: 462.41 g/mol

Ref: 3D-AAA06531