CAS 6500-81-8
:Sodium ethacrynate
Description:
Sodium ethacrynate is a chemical compound classified as a loop diuretic, primarily used in medical applications to promote diuresis, which is the increased production of urine. It is a sodium salt of ethacrynic acid, and its mechanism of action involves inhibiting the sodium-potassium-chloride co-transporter in the thick ascending limb of the loop of Henle in the kidneys. This inhibition leads to increased excretion of sodium, chloride, and water, making it effective in treating conditions such as edema associated with heart failure, liver cirrhosis, and renal disorders. Sodium ethacrynate is typically administered intravenously or orally, depending on the clinical scenario. The compound is known for its potential side effects, which may include electrolyte imbalances, dehydration, and ototoxicity, particularly with rapid administration or high doses. As with any medication, careful monitoring of renal function and electrolyte levels is essential during treatment. Its chemical structure includes a phenoxy group and a carboxylic acid, contributing to its pharmacological properties.
Formula:C13H12Cl2O4·Na
InChI:InChI=1S/C13H12Cl2O4.Na/c1-3-7(2)13(18)8-4-5-9(12(15)11(8)14)19-6-10(16)17;/h4-5H,2-3,6H2,1H3,(H,16,17);
InChI key:InChIKey=OPVSUVQQYHPGOZ-UHFFFAOYSA-N
SMILES:C(C(CC)=C)(=O)C1=C(Cl)C(Cl)=C(OCC(O)=O)C=C1.[Na]
Synonyms:- Ethacrynic acid sodium
- Sodium Ethacrynate
- Acetic acid, 2-[2,3-dichloro-4-(2-methylene-1-oxobutyl)phenoxy]-, sodium salt (1:1)
- Lyovac sodium edecrin
- Ethacrynate
- Edecrin Sodium
- Sodium edecrin
- Sodium (2,3-dichloro-4-(2-methylenebutyryl)phenoxy)acetate
- Acetic acid, [2,3-dichloro-4-(2-methylenebutyryl)phenoxy]-, sodium salt
- Acetic acid, (2,3-dichloro-4-(2-methylene-1-oxobutyl)phenoxy)-, sodium salt
- Ethacrynate Sodium [USAN]
- Acetic acid, [2,3-dichloro-4-(2-methylene-1-oxobutyl)phenoxy]-, sodium salt
- UNII-K41MYV7MPM
- Sodium [2,3-dichloro-4-(2-methylenebutyryl)phenoxy]acetate
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Found 1 products.
Ethacrynate Sodium
CAS:<p>Ethacrynate Sodium, a sodium salt, blocks chloride, potassium, and sodium transport mainly in Henle's loop.</p>Formula:C13H12Cl2NaO4Purity:98%Color and Shape:SolidMolecular weight:326.12
