CAS 65004-42-4

2-(3,5-Dimethyl-1H-pyrazol-1-yl)-6-methylpyrimidin-4(3H)-one

CAS: 65004-42-4

2-(3,5-Dimethyl-1H-pyrazol-1-yl)-6-methylpyrimidin-4(3H)-one

Purity: 97%

Molecular weight: 204.23g/mol

Ref: 54-OR1058071

2-(3,5-Dimethyl-1H-pyrazol-1-yl)-6-methylpyrimidin-4-ol

CAS: 65004-42-4

2-(3,5-Dimethyl-1H-pyrazol-1-yl)-6-methylpyrimidin-4-ol is a tautomeric form of 2-(3,5-dimethylpyrazol-1-yl)-6-[(2R,3S)-3,5-dimethoxyphenyl]pyrimidin-4-ol. It is a potent inhibitor of lipases and has been shown to have antiinflammatory properties. The drug has also been found to decrease the number of inflammatory cells in the bowel and can be used for the treatment of inflammatory bowel disease. The drug may also be effective for treating other autoimmune diseases such as thyroiditis and scleroderma. This drug also has cancer prevention effects because it inhibits cell division and tumor growth by binding to DNA.

Formula: C₁₀H₁₂N₄O

Purity: Min. 95%

Molecular weight: 204.23 g/mol

Ref: 3D-QCA00442

Pyrimidinone 8

CAS: 65004-42-4

Pyrimidinone 8 is a reversible, linear non-competitive inhibitor of divalent metal transporter 1 (DMT1) with a Ki of 20 μM (hDMT1). It does not affect the surface expression of hDMT1 and is not influenced by extracellular pH. Pyrimidinone 8 inhibits hDMT1-mediated iron uptake, with an IC50 of 13.8 μM.

Formula: C₁₀H₁₂N₄O

Color and Shape: Solid

Molecular weight: 204.229

Ref: TM-T205042