CAS 6504-57-0

Tiemonium methosulfate

Description:

Tiemonium methosulfate is a quaternary ammonium compound primarily used as an antispasmodic agent in the treatment of gastrointestinal disorders. It is characterized by its ability to relax smooth muscles, making it effective in alleviating symptoms associated with conditions like irritable bowel syndrome. The compound is typically presented as a white to off-white powder and is soluble in water, which facilitates its use in various pharmaceutical formulations. Tiemonium methosulfate acts by blocking the action of acetylcholine at muscarinic receptors, thereby reducing spasms and discomfort. Its pharmacological profile includes a relatively low toxicity, making it suitable for therapeutic applications. Additionally, it is important to note that, like many quaternary ammonium compounds, it may exhibit antimicrobial properties, which can be beneficial in certain formulations. However, its use should be monitored for potential side effects, including dry mouth and blurred vision, which are common with anticholinergic medications. Overall, Tiemonium methosulfate is a valuable compound in the field of gastroenterology.

Formula: C₁₉H₂₇NO₆S₂

InChI: InChI=1/C18H24NO2S.CH4O4S/c1-19(11-13-21-14-12-19)10-9-18(20,17-8-5-15-22-17)16-6-3-2-4-7-16;1-5-6(2,3)4/h2-8,15,20H,9-14H2,1H3;1H3,(H,2,3,4)/q+1;/p-1

InChI key: InChIKey=JPOKDEDHVLJMIJ-UHFFFAOYSA-M

SMILES: S(OC)(=O)(=O)[O-].C(CC[N+]1(C)CCOCC1)(O)(C2=CC=CS2)C3=CC=CC=C3

Synonyms:

• 4-(3-Hydroxy-3-phenyl-3-(2-thienyl)propyl)-4-methylmorpholinium, methyl sulfate (salt)
• 4-[3-Hydroxy-3-Phenyl-3-(Thiophen-2-Yl)Propyl]-4-Methylmorpholin-4-Ium Methyl Sulfate
• 4-[3-Hydroxy-3-phenyl-3-(2-thienyl)propyl]-4-methylmorpholinium methyl sulfate
• Morpholinium, 4-[3-hydroxy-3-phenyl-3-(2-thienyl)propyl]-4-methyl-, methyl sulfate (1:1)
• Morpholinium, 4-[3-hydroxy-3-phenyl-3-(2-thienyl)propyl]-4-methyl-, methyl sulfate (salt)
• Tiemonium methosulfate
• Tiemonium methosulphate
• Tiemonium methylsulfate
• 4-(3-Hydroxy-3-phenyl-3-(2-thienyl)propyl)-4-methylmorpholinium methyl sulphate
• Tiemonium Metilsulfate
• Tiemoniummethylsulfate
• Einecs 229-386-0
• 4-(3-Hydroxy-3-phenyl-3-(thiophen-2-yl)propyl)-4-methylmorpholin-4-iummethylsulfate

Tiemonium Methyl Sulfate

CAS: 6504-57-0

Applications Tiemonium Methyl Sulfate is an antispasmodic drug.
References Islam, M. S., et al.: Int. J. Pharm. Sci. Res., 5, 548 (2014)

Formula: C₁₈H₂₄NO₂S·CH₃O₄S

Color and Shape: Neat

Molecular weight: 429.551

Ref: TR-T438760