CAS 65052-63-3

Cefetamet

Description:

Cefetamet is a broad-spectrum cephalosporin antibiotic, classified under the β-lactam group of antibiotics. It is primarily used to treat various bacterial infections by inhibiting bacterial cell wall synthesis, which ultimately leads to cell lysis and death. Cefetamet is effective against both Gram-positive and Gram-negative bacteria, making it a versatile option in clinical settings. The compound is typically administered in its prodrug form, which is converted to its active form in the body. It exhibits good oral bioavailability and is often used to treat respiratory tract infections, urinary tract infections, and skin infections. The chemical structure of cefetamet includes a β-lactam ring, which is essential for its antibacterial activity, and a side chain that enhances its stability against certain β-lactamases produced by resistant bacteria. As with other antibiotics, appropriate use is crucial to minimize the development of resistance. Side effects may include gastrointestinal disturbances and allergic reactions, similar to other cephalosporins.

Formula: C₁₄H₁₅N₅O₅S₂

InChI: InChI=1S/C14H15N5O5S2/c1-5-3-25-12-8(11(21)19(12)9(5)13(22)23)17-10(20)7(18-24-2)6-4-26-14(15)16-6/h4,8,12H,3H2,1-2H3,(H2,15,16)(H,17,20)(H,22,23)/b18-7-/t8-,12-/m1/s1

InChI key: InChIKey=MQLRYUCJDNBWMV-GHXIOONMSA-N

SMILES: C(O)(=O)C=1N2[C@@]([C@H](NC(/C(=N\OC)/C=3N=C(N)SC3)=O)C2=O)(SCC1C)[H]

Synonyms:

• (6R,7R)-7-[[(2Z)-2-(2-Amino-4-thiazolyl)-2-(methoxyimino)acetyl]amino]-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
• (6R,7R)-7-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino}-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
• 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[(2-amino-4-thiazolyl)(methoxyimino)acetyl]amino]-3-methyl-8-oxo-, [6R-[6α,7β(Z)]]-
• 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[(2Z)-(2-amino-4-thiazolyl)(methoxyimino)acetyl]amino]-3-methyl-8-oxo-, (6R,7R)-
• 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[(2Z)-2-(2-amino-4-thiazolyl)-2-(methoxyimino)acetyl]amino]-3-methyl-8-oxo-, (6R,7R)-
• Altamet
• Antibiotic Ro 15-8074
• Cefetamet
• Cefetamet hydrochloride
• Cepime O
• Deacetoxycefotaxime
• Fr 13300
• Ly 97964
• Ro 15-8074
• Ro 15-8074/005

Cefetamet

CAS: 65052-63-3

Antibiotics nesoi

Formula: C₁₄H₁₅N₅O₅S₂

Color and Shape: White Powder

Molecular weight: 397.05146

Ref: 45-1097727

5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid,7-[[(2Z)-(2-amino-4-thiazolyl)(methoxyimino)acetyl]amino]-3-methyl-8-oxo-, (6R,7R)-

CAS: 65052-63-3

Formula: C₁₄H₁₅N₅O₅S₂

Purity: 97%

Color and Shape: Solid

Molecular weight: 397.4294

Ref: IN-DA01CCI8

Cefotaxime EP Impurity A (Cefetamet)

CAS: 65052-63-3

Formula: C₁₄H₁₅N₅O₅S₂

Color and Shape: White To Off-White Solid

Molecular weight: 397.42

Ref: 4Z-C-106003

Cefetamet-d3

Controlled Product

CAS: 65052-63-3

Applications Labelled Cefetamet is a third-generation cephalosporin antibiotic and the active agent of Cefeamet pivoxil (C242780) after hydrolysis.
References Bryson, H.M., et al.: Drugs., 45, 589 (1993); Sharma, R.K., et al.: Asian. J. Biochem. Pharmaceut. Res., 1, 443 (2011); Waters, N.J., et al.: Drug. Metabolism. Disposit., 38, 1159 (2010);

Formula: C₁₄H₁₂D₃N₅O₅S₂

Color and Shape: White To Off-White

Molecular weight: 400.45

Ref: TR-C242772

Cefetamet

CAS: 65052-63-3

Impurity Cefotaxime Sodium EP Impurity A
Stability Hygroscopic
Applications Cefetamet is a third-generation cephalosporin antibiotic and the active agent of Cefeamet pivoxil (C242780) after hydrolysis.
References Bryson, H.M., et al.: Drugs., 45, 589 (1993); Sharma, R.K., et al.: Asian. J. Biochem. Pharmaceut. Res., 1, 443 (2011); Waters, N.J., et al.: Drug. Metabolism. Disposit., 38, 1159 (2010);

Formula: C₁₄H₁₅N₅O₅S₂

Color and Shape: Off-White

Molecular weight: 397.43

Ref: TR-C242770

Cefetamet acid;Cefetamet;Deacetoxycefotaxime

CAS: 65052-63-3

Formula: C₁₄H₁₅N₅O₅S₂

Purity: 97%

Color and Shape: Solid

Molecular weight: 397.42

Ref: 10-F041377

Cefotaxime Sodium EP Impurity A

CAS: 65052-63-3

Formula: C₁₄H₁₅N₅O₅S₂

Molecular weight: 397.42

Ref: ST-EA-CP-C123001