CAS 6506-37-2

Nimorazole

Description:

Nimorazole is an antiprotozoal and antimicrobial agent primarily used in the treatment of infections caused by anaerobic bacteria and certain protozoa. It belongs to the class of nitroimidazoles, which are characterized by their nitro group attached to an imidazole ring. This compound exhibits a broad spectrum of activity against various microorganisms, making it effective in treating conditions such as bacterial vaginosis and certain parasitic infections. Nimorazole works by disrupting the DNA synthesis of the target organisms, leading to cell death. It is typically administered orally and is well-absorbed in the gastrointestinal tract. The substance is known for its relatively low toxicity profile, although side effects may include gastrointestinal disturbances and allergic reactions in some individuals. As with other nitroimidazoles, caution is advised in patients with a history of neurological disorders or those consuming alcohol, as interactions may occur. Overall, nimorazole is a valuable therapeutic agent in the field of infectious diseases, particularly in regions where resistant strains of pathogens are prevalent.

Formula: C₉H₁₄N₄O₃

InChI: InChI=1S/C9H14N4O3/c14-13(15)9-7-10-8-12(9)2-1-11-3-5-16-6-4-11/h7-8H,1-6H2

InChI key: InChIKey=MDJFHRLTPRPZLY-UHFFFAOYSA-N

SMILES: C(CN1CCOCC1)N2C(N(=O)=O)=CN=C2

Synonyms:

• 1-(.beta.-Morpholinoethyl)-5-nitroimidazole
• 1-(Morpholinoethyl)-5-nitroimidazole
• 1-(β-Morpholinoethyl)-5-nitroimidazole
• 229-394-4
• 4-[2-(5-Nitroimidazol-1-yl)ethyl]morpholine
• 4-[2-(5-nitro-1H-imidazol-1-yl)ethyl]morpholine
• 6506-37-2
• Acterol
• Esclama
• K-1900
• Morpholine, 4-[2- (5-nitro-1H-imidazol-1-yl)ethyl]-
• Morpholine, 4-[2- (5-nitroimidazol-1-yl)ethyl]-
• NSC 107524
• Naxofem
• Naxogin
• Nimorazol
• Nitrimidazine

Nimorazole

CAS: 6506-37-2

Nimorazole

Purity: ≥98%

Molecular weight: 226.23g/mol

Ref: 54-BUP16268

Nimorazole

CAS: 6506-37-2

Formula: C₉H₁₄N₄O₃

Color and Shape: Neat

Molecular weight: 226.23

Ref: 04-C15527000

Nimorazole

CAS: 6506-37-2

Nimorazole (Nimorazol) is a nitroimidazole anti-infective.

Formula: C₉H₁₄N₄O₃

Purity: 98.21% - 98.54%

Color and Shape: Solid

Molecular weight: 226.23

Ref: TM-T2046

Nimorazole

CAS: 6506-37-2

Formula: C₉H₁₄N₄O₃

Molecular weight: 226.24

Ref: 4Z-N-058001

Nimorazole

CAS: 6506-37-2

Nimorazole

Purity: 99%

Molecular weight: 226.23g/mol

Ref: 54-BISN0007

Nimorazole

Controlled Product

CAS: 6506-37-2

Applications Nimorazole is an antimicrobial with activity against anaerobic bacteria and protozoa.
References Ratnaparkhi, M.P., et al.: Res. J. Pharma. BIol. Chem. Sci., 3, 303 (2012); Toustrup, K., et al.: Radiotherap. Oncol., 102, 122 (2012);

Formula: C₉H₁₄N₄O₃

Color and Shape: Neat

Molecular weight: 226.23

Ref: TR-N478250

4-(2-(5-Nitro-1H-imidazol-1-yl)ethyl)morpholine

CAS: 6506-37-2

Formula: C₉H₁₄N₄O₃

Purity: ≥98%

Molecular weight: 226.236

Ref: 10-F340031

Nimorazole-d8

Controlled Product

CAS: 6506-37-2

Formula: C₉D₈H₆N₄O₃

Color and Shape: Neat

Molecular weight: 234.282

Ref: TR-N478252

Nimorazole

CAS: 6506-37-2

Nimorazole is a new antibiotic that binds to the receptor site of metronidazole, which is an antibiotic and antiprotozoal agent. Nimorazole has been shown to be effective in treating autoimmune diseases by inhibiting the production of cytokines and chemokines. It also has a high affinity for bacterial DNA gyrase, topoisomerase IV, and RNA polymerase. The binding of nimorazole to these enzymes leads to the inhibition of protein synthesis, leading to cell death by inhibiting the production of proteins vital for cell division. Nimorazole may also have a role in treating infectious diseases such as diarrhoea because it inhibits the growth of bacteria such as Escherichia coli and Clostridium difficile through its inhibitory effects on protein synthesis.

Formula: C₉H₁₄N₄O₃

Purity: Min. 95%

Molecular weight: 226.23 g/mol

Ref: 3D-GAA50637