CAS 65100-49-4

3-(5,6-dihydrobenzo[b][1]benzazepin-11-yl)-N-(trideuteriomethyl)propan-1-amine

Description:

3-(5,6-dihydrobenzo[b][1]benzazepin-11-yl)-N-(trideuteriomethyl)propan-1-amine, with CAS number 65100-49-4, is a chemical compound that belongs to the class of substituted amines. Its structure features a complex bicyclic system, which includes a benzazepine moiety, indicating potential biological activity. The presence of the trideuteriomethyl group suggests that this compound has been isotopically labeled, which can be useful in pharmacokinetic studies or metabolic tracing. The compound's amine functional group typically indicates basic properties and potential interactions with biological systems, such as neurotransmitter receptor binding. Additionally, the dihydrobenzo structure may contribute to its lipophilicity, influencing its solubility and permeability in biological membranes. Overall, this compound's unique structural features may confer specific pharmacological properties, making it of interest in medicinal chemistry and drug development. However, detailed studies would be necessary to elucidate its precise biological effects and potential applications.

Formula: C₁₈H₁₉D₃N₂

InChI: InChI=1/C18H22N2/c1-19-13-6-14-20-17-9-4-2-7-15(17)11-12-16-8-3-5-10-18(16)20/h2-5,7-10,19H,6,11-14H2,1H3/i1D3

SMILES: C(NCCCN1c2ccccc2CCc2ccccc12)([2H])([2H])[2H]

Desipramine-d3

Controlled Product

CAS: 65100-49-4

Applications Labelled tricyclic antidepressant that is a more potent inhibitor of the norepinephrine transporter than the serotonin transporter.
References Klerman, G.L., et al.: Pharmacol. Rev., 17, 101 (1965), Checkley, S.A, et al.: Br. J. Psychiatry, 138. 248 (1981), Zhu, M.Y., et al.: J. Neurochem., 70, 1547 (1998), Okugawa, G., et al.: J. Neuroindocrinol., 11, 887 (1999), Torres, G.E., et al.: Nat. Rev. Neurosci., 4, 13 (2003),

Formula: C₁₈₂H₃H₂₀N₃

Color and Shape: Neat

Molecular weight: 284.41

Ref: TR-D290053