
CAS 65144-53-8
:Androstane- 3alpha,17 beta-diol glucuronide
Description:
Androstane-3α,17β-diol glucuronide is a steroid compound that serves as a metabolite of androgens, specifically dihydrotestosterone (DHT) and testosterone. It is characterized by the presence of a glucuronic acid moiety, which enhances its solubility and facilitates excretion from the body. This compound plays a significant role in the metabolism of steroid hormones and is often analyzed in clinical and research settings to assess androgen levels and steroid metabolism. Its structure includes a steroid backbone with hydroxyl groups at the 3α and 17β positions, which are crucial for its biological activity. The glucuronidation process, which involves the conjugation of glucuronic acid, typically occurs in the liver and is a common pathway for the detoxification and elimination of various endogenous and exogenous substances. As a glucuronide, it is generally more water-soluble than its parent steroid, allowing for easier renal excretion. The study of androstane-3α,17β-diol glucuronide is important in endocrinology, particularly in understanding hormonal balance and disorders related to androgen metabolism.
Formula:C25H40O8
Synonyms:- Androstane -3,17- diol 17- glucuronide
- Androstane- 3alpha,17 beta-diol glucuronide
- β-D-Glucopyranosiduronic acid, (3β,5α,17β)-3-hydroxyandrostan-17-yl
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