CAS 65147-04-8

N-(tert-butoxycarbonyl)-L-valyl-N-{(2S)-5-[(diaminomethylidene)amino]-2-[(4-methyl-2-oxo-2H-chromen-7-yl)amino]pentanoyl}-L-prolinamide

Description:

N-(tert-butoxycarbonyl)-L-valyl-N-{(2S)-5-[(diaminomethylidene)amino]-2-[(4-methyl-2-oxo-2H-chromen-7-yl)amino]pentanoyl}-L-prolinamide, with CAS number 65147-04-8, is a complex organic compound characterized by its peptide structure and specific functional groups. It features a tert-butoxycarbonyl (Boc) protecting group, which is commonly used in peptide synthesis to protect amine functionalities. The molecule contains L-valine and L-proline residues, indicating its relevance in peptide chemistry and potential biological activity. The presence of a diaminomethylidene group suggests potential reactivity and interaction with biological targets, while the chromen-7-yl moiety may impart additional pharmacological properties. This compound is likely to be soluble in organic solvents and may exhibit specific interactions with biological macromolecules, making it of interest in medicinal chemistry and drug design. Its structural complexity and functional diversity suggest potential applications in therapeutic development, particularly in the context of peptide-based drugs or as a building block in larger molecular architectures.

Formula: C₃₁H₄₅N₇O₇

InChI: InChI=1/C31H45N7O7/c1-17(2)25(36-30(43)45-31(4,5)6)28(42)38-14-8-10-22(38)27(41)37-26(40)21(9-7-13-34-29(32)33)35-19-11-12-20-18(3)15-24(39)44-23(20)16-19/h11-12,15-17,21-22,25,35H,7-10,13-14H2,1-6H3,(H,36,43)(H4,32,33,34)(H,37,40,41)/t21-,22-,25-/m0/s1

SMILES: CC(C)[C@@H](C(=O)N1CCC[C@H]1C(=O)N=C([C@H](CCCNC(=N)N)Nc1ccc2c(C)cc(=O)oc2c1)O)N=C(O)OC(C)(C)C

Synonyms:

• Boc-Val-Pro-Arg-Mca

Boc-Val-Pro-Arg-AMC

CAS: 65147-04-8

Boc-VPR-AMC, a specific, highly fluorogenic substrate for thrombin and the thrombin-staphylocoagulase complex. The thrombin assay has been used for the indirect determination of coagulation factor III. Trypsin, tryptase from rat mast cells, and two trypsin-like enzymes from sperm of the ascidian Halocynthia roretzi, acrosin and spermosin, also hydrolyze this substrate. Furthermore, Boc-VPR-AMC is cleaved by the Kex2 endoprotease (kexin, previously known as proteinase yscF), a membrane-bound, calcium-dependent serine protease from yeast α-cells. Kinetic data for Thrombin: kcat = 105, Km = 21 uM.

Formula: C₃₁H₄₅N₇O₇

Purity: > 99%

Color and Shape: White Powder

Molecular weight: 627.74

Ref: 01-4003460

Boc-Val-Pro-Arg-AMC

CAS: 65147-04-8

Boc-Val-Pro-Arg-AMC is a peptide that activates ion channels. It is an agonist of the nicotinic acetylcholine receptor (nAChR) and can be used in research to investigate the pharmacology of nAChRs. Boc-Val-Pro-Arg-AMC can also be used as a high purity ligand for antibody production, which has applications in cell biology and other life science research.

Formula: C₃₁H₄₅N₇O₇

Purity: Min. 95%

Molecular weight: 627.73 g/mol

Ref: 3D-MVP-3093-V

Boc-Val-Pro-Arg-AMC

CAS: 65147-04-8

Please enquire for more information about Boc-Val-Pro-Arg-AMC including the price, delivery time and more detailed product information at the technical inquiry form on this page

Formula: C₃₁H₄₅N₇O₇

Purity: Min. 95%

Molecular weight: 627.73 g/mol

Ref: 3D-FB110488