CAS 65184-10-3

Teoprolol

Description:

The chemical substance known as "Teoprolol," with the CAS number 65184-10-3, is a beta-blocker primarily used in the treatment of cardiovascular conditions, including hypertension and certain types of arrhythmias. It functions by selectively blocking beta-adrenergic receptors, which helps to reduce heart rate and lower blood pressure. Teoprolol is characterized by its ability to improve cardiac output and decrease myocardial oxygen demand, making it beneficial for patients with heart-related issues. The compound is typically administered orally and is known for its relatively favorable side effect profile compared to other beta-blockers. Its pharmacokinetics include moderate absorption and a significant first-pass metabolism, which influences its bioavailability. Teoprolol is often prescribed in conjunction with lifestyle modifications and other medications to optimize cardiovascular health. As with any medication, monitoring for potential side effects, such as fatigue or dizziness, is essential during treatment. Overall, Teoprolol represents an important therapeutic option in the management of various cardiovascular diseases.

Formula: C₂₃H₃₀N₆O₄

InChI: InChI=1/C23H30N6O4/c1-14(8-9-29-13-25-21-20(29)22(31)28(4)23(32)27(21)3)24-11-16(30)12-33-19-7-5-6-18-17(19)10-15(2)26-18/h5-7,10,13-14,16,24,26,30H,8-9,11-12H2,1-4H3

InChI key: InChIKey=HITMZSXZYGLDCV-UHFFFAOYSA-N

SMILES: C(CC(NCC(COC1=C2C(NC(C)=C2)=CC=C1)O)C)N3C4=C(N=C3)N(C)C(=O)N(C)C4=O

Synonyms:

• 1H-Purine-2,6-dione, 3,7-dihydro-7-(3-((2-hydroxy-3-((2-methyl-1H-indol-4-yl)oxy)propyl)amino)butyl)-1,3-dimethyl-
• 3,7-Dihydro-7-[3-[[2-hydroxy-3-[(2-methyl-1H-indol-4-yl)oxy]propyl]amino]butyl]-1,3-dimethyl-1H-purine-2,6-dione
• 7-(3-((2-Hydroxy-3-((2-methylindol-4-yl)oxy)propyl)amino)butyl)theophylline
• 7-[3-({2-hydroxy-3-[(2-methyl-1H-indol-4-yl)oxy]propyl}amino)butyl]-1,3-dimethyl-3,7-dihydro-1H-purine-2,6-dione
• Brn 1234202
• D-13,312
• Teoprolol [INN]
• Teoprololum
• Teoprololum [INN-Latin]
• Teoprolol
• 5-26-14-00031 (Beilstein Handbook Reference)

Teoprolol

Controlled Product

CAS: 65184-10-3

Teoprolol is a beta-adrenergic antagonist that competes with catecholamines for binding to the beta-adrenergic receptors in the heart. It is used to treat ventricular dysfunction and cardiac arrhythmia and has been shown to be effective against congestive heart failure. Teoprolol is a prodrug, which means it is not active when taken orally; it must be reconstituted before administration. The drug's effects are due to its ability to block the catecholamine receptor, preventing stimulation of the cardiac muscle. This causes an increase in fatty acid oxidation and decrease in lipoprotein levels, resulting in decreased cholesterol levels. Teoprolol also inhibits enzymes that produce fatty alcohols and amides, which can lead to decreased cardiac arrhythmias.

Formula: C₂₃H₃₀N₆O₄

Purity: Min. 95%

Molecular weight: 454.5 g/mol

Ref: 3D-QCA18410

Teoprolol

CAS: 65184-10-3

Teoprolol is a blocker of β-adrenergic receptor.

Formula: C₂₃H₃₀N₆O₄

Purity: 98%

Color and Shape: Solid

Molecular weight: 454.52

Ref: TM-T13124