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CAS 65195-58-6

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Avermectin B2b

Description:
Avermectin B2b is a macrocyclic lactone compound that belongs to the avermectin family, which is derived from the fermentation of the bacterium Streptomyces avermitilis. It is primarily known for its potent antiparasitic and insecticidal properties, making it widely used in veterinary medicine and agriculture. Avermectin B2b exhibits a complex structure characterized by a large lactone ring and multiple functional groups, contributing to its biological activity. The compound acts by interfering with the neurotransmission in parasites, leading to paralysis and death. It is effective against a variety of nematodes and arthropods, making it valuable in controlling pests in crops and livestock. Avermectin B2b is typically administered in formulations that ensure stability and bioavailability. Safety considerations are important, as it can have toxic effects on non-target organisms, particularly aquatic life. Therefore, its use is regulated, and appropriate measures are taken to minimize environmental impact. Overall, Avermectin B2b is a significant compound in the field of pest management and veterinary therapeutics.
Formula:C47H72O15
InChI:InChI=1/C47H72O15/c1-23(2)41-27(6)34(48)21-46(62-41)20-32-17-31(61-46)15-14-25(4)42(24(3)12-11-13-30-22-55-44-39(49)26(5)16-33(45(51)58-32)47(30,44)52)59-38-19-36(54-10)43(29(8)57-38)60-37-18-35(53-9)40(50)28(7)56-37/h11-14,16,23-24,27-29,31-44,48-50,52H,15,17-22H2,1-10H3/b12-11-,25-14-,30-13-/t24-,27-,28-,29-,31+,32-,33-,34?,35-,36-,37-,38-,39+,40-,41+,42-,43-,44+,46-,47+/m0/s1
Synonyms:
  • Spiro[11,15-methano-2H,7H,13H-furo[4,3,2-pq][2,6]benzodioxacyclooctadecin-13,2′-[2H]pyran], avermectin A1a deriv.
  • Antibiotic C 076B2b
  • Avermectin Ala, 5-O-demethyl-25-de(1-methylpropyl)-22,23-dihydro-23-hydroxy-25-(1-methylethyl)-, (23S)-
  • Avermectine B2b
  • Avermectin B2b
  • (23S)-5-O-Demethyl-25-de(1-methylpropyl)-22,23-dihydro-23-hydroxy-25-(1-methylethyl)avermectin A1a
  • Avermectin A1a, 5-O-demethyl-25-de(1-methylpropyl)-22,23-dihydro-23-hydroxy-25-(1-methylethyl)-, (23S)-
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