CAS 652-37-9

Acefylline

Description:

Acefylline, with the CAS number 652-37-9, is a chemical compound that belongs to the class of xanthine derivatives, which are known for their pharmacological properties. It is primarily recognized for its use as a bronchodilator, aiding in the treatment of respiratory conditions such as asthma and chronic obstructive pulmonary disease (COPD). The compound exhibits characteristics typical of xanthines, including the ability to relax bronchial smooth muscle and improve airflow. Acefylline is soluble in water, which facilitates its administration in various pharmaceutical formulations. Its mechanism of action involves the inhibition of phosphodiesterase, leading to increased levels of cyclic AMP, which contributes to bronchodilation. Additionally, it may possess anti-inflammatory properties, making it beneficial in managing respiratory inflammation. However, like other xanthines, it may have side effects such as gastrointestinal disturbances and cardiovascular effects, necessitating careful monitoring during use. Overall, acefylline is a valuable compound in respiratory therapy, contributing to improved patient outcomes in managing airway diseases.

Formula: C₉H₁₀N₄O₄

InChI: InChI=1/C9H10N4O4/c1-11-7-6(8(16)12(2)9(11)17)13(4-10-7)3-5(14)15/h4H,3H2,1-2H3,(H,14,15)/p-1

InChI key: InChIKey=HCYFGRCYSCXKNQ-UHFFFAOYSA-N

SMILES: C(C(O)=O)N1C2=C(N(C)C(=O)N(C)C2=O)N=C1

Synonyms:

• (1,3-dimethyl-2,6-dioxo-1,2,3,6-tetrahydro-7H-purin-7-yl)acetate
• (1,3-dimethyl-2,6-dioxo-1,2,3,6-tetrahydro-7H-purin-7-yl)acetic acid
• 1,2,3,6-Tetrahydro-1,3-dimethyl-2,6-dioxo-7H-purine-7-acetic acid
• 1,2,3,6-Tetrahydro-1,3-dimethyl-2,6-dioxopurine-7-acetic acid
• 2-(1,3-Dimethyl-2,6-dioxo-2,3,6,7-tetrahydro-1H-purin-7-yl)acetic acid
• 2-(1,3-Dimethyl-2,6-dioxo-2,3-dihydro-1H-purin-7(6H)-yl)acetic acid
• 2-(1,3-Dimethyl-2,6-dioxopurin-7-yl)acetic acid
• 7-(Carboxymethyl)theophylline
• 7-Theophyllineacetic acid
• 7-Theophyllinylacetic acid
• 7H-Purine-7-acetic acid, 1,2,3,6-tetrahydro-1,3-dimethyl-2,6-dioxo-
• Acefylline
• Acephylline
• Carboxymethyltheophylline
• N-7-Theophyllineacetic acid
• NSC 52996
• Purine-7-acetic acid, 1,2,3,6-tetrahydro-1,3-dimethyl-2,6-dioxo-
• Theophyllineacetic acid
• CAFFEINE CARBOXYLIC ACID
• THEOPHYLINE ACETIC ACID
• LABOTEST-BB LT00053164
• THEOPHYLLINE-7-ACETIC ACID
• 1,2,3,6-tetrahydro-1,3-dimethyl-2,6-dioxopurine-7-aceticacid
• (1,3-DIMETHYL-2,6-DIOXO-1,2,3,6-TETRAHYDRO-PURIN-7-YL)-ACETIC ACID
• theophyllin-7-ylacetic acid
• 1,2,3,6-tetrahydro-1,3-dimethyl-2,6-dioxo-purine-7-aceticaci
• Theophylline-7-aceticacid,98%
• 7-theophyllinylaceticacid
• acidetheophylline-ethanoique-7
• 7-Theophyline Acetic Acid
• 1,3-DIMETHYLXANTHINE-7-ACETIC ACID
• 7-THEOPHYLLINE ACETIC ACID

Theophylline-7-acetic Acid

CAS: 652-37-9

Formula: C₉H₁₀N₄O₄

Purity: >98.0%(T)(HPLC)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 238.20

Ref: 3B-T2941

Theophylline-7-acetic acid, 98%

CAS: 652-37-9

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Formula: C₉H₁₀N₄O₄

Purity: 98%

Color and Shape: White, Powder

Molecular weight: 238.2

Ref: 02-A11473

Acefylline

CAS: 652-37-9

Color and Shape: Neat

Ref: 61-FOR1727.00

7H-Purine-7-aceticacid, 1,2,3,6-tetrahydro-1,3-dimethyl-2,6-dioxo-

CAS: 652-37-9

Formula: C₉H₁₀N₄O₄

Purity: %

Color and Shape: Solid

Molecular weight: 238.2001

Ref: IN-DA00E8M5

Acefylline

CAS: 652-37-9

Acefylline (Theophylline-7-acetic acid), a stimulant drug of the xanthine chemical class, acts as an adenosine receptor antagonist.

Formula: C₉H₁₀N₄O₄

Purity: 99.57%

Color and Shape: White Crystalline Solid

Molecular weight: 238.2

Ref: TM-T2205

Theophylline 7-Acetic Acid

CAS: 652-37-9

Formula: C₉H₁₀N₄O₄

Color and Shape: White To Off-White Solid

Molecular weight: 238.20

Ref: 4Z-T-601

2-(1,3-Dimethyl-2,6-Dioxo-1,2,3,6-Tetrahydro-7H-Purin-7-Yl)Acetic Acid

CAS: 652-37-9

2-(1,3-Dimethyl-2,6-Dioxo-1,2,3,6-Tetrahydro-7H-Purin-7-Yl)Acetic Acid

Purity: 98%

Molecular weight: 238.2g/mol

Ref: 54-OR1023637

Acefylline

CAS: 652-37-9

Acefylline

Purity: ≥98%

Molecular weight: 238.2g/mol

Ref: 54-BUP14684

Acefylline (Theophylline-7-acetic acid)

CAS: 652-37-9

Formula: C₉H₁₀N₄O₄

Purity: ≥ 98.0%

Color and Shape: White to off-white powder

Molecular weight: 238.20

Ref: 7W-GK1607

Acefylline

Controlled Product

CAS: 652-37-9

Formula: C₉H₁₀N₄O₄

Color and Shape: Neat

Molecular weight: 238.20

Ref: 86-MM1727.00

Theophylline-7-acetic Acid

Controlled Product

CAS: 652-37-9

Applications A xanthine derivative with bronchodilator activity. Typically combined as salt component with other medications such as Ambroxol to treat bronchial and pulmonary diseases.
References Kim, S., et al.: J. Med. Chem., 45, 2131 (2002), Bruno-Blanch, L., et al.: Bioorg. Med. Chem. Lett., 13, 2749 (2003), Foppoli, A., et al.: J. Pharm. Sci., 96, 1139(2007),

Formula: C₉H₁₀N₄O₄

Color and Shape: Neat

Molecular weight: 238.20

Ref: TR-T343860

Theophylline-7-acetic acid

CAS: 652-37-9

Formula: C₉H₁₀N₄O₄

Purity: 98%

Color and Shape: Solid, White to almost white powder

Molecular weight: 238.203

Ref: 10-F037330

Theophylline-7-acetic acid

Controlled Product

CAS: 652-37-9

Theophylline-7-acetic acid is a substance that has the chemical name of 2-amino-5-(1,3-dimethylxanthin-9-yl)benzoic acid. It is an amorphous substance with a biochemical property of being soluble in water and ethanol. Theophylline-7-acetic acid is used as a reagent for the quantitative determination of cardiac glycosides in human serum. This compound also reacts with a solution of sodium salts under constant pressure at room temperature and an electrochemical detector to yield an intense blue fluorescence. Structural analysis indicates that this substance contains a hydroxyl group, which can be found in proteins, fatty acids, and pharmacokinetics.

Formula: C₉H₁₀N₄O₄

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 238.2 g/mol

Ref: 3D-FT28197

Theophylline 7-Acetic Acid

CAS: 652-37-9

Formula: C₉H₁₀N₄O₄

Molecular weight: 238.2

Ref: ST-EA-CP-T59011