CAS 652-67-5

Isosorbide

Description:

Isosorbide, with the CAS number 652-67-5, is a bicyclic organic compound derived from sorbitol. It is a colorless, crystalline solid that is soluble in water and polar organic solvents. Isosorbide is primarily known for its use as a building block in the synthesis of polymers and as a plasticizer due to its favorable mechanical properties. It exhibits a melting point typically around room temperature and has a relatively low vapor pressure, making it stable under standard conditions. The compound features two hydroxyl groups, which contribute to its reactivity and ability to form hydrogen bonds, enhancing its solubility in various solvents. Isosorbide is also recognized for its biodegradable properties, making it an attractive alternative in the development of sustainable materials. Additionally, it has applications in the pharmaceutical industry, particularly in drug formulation, due to its biocompatibility. Overall, isosorbide is valued for its versatility in both industrial and pharmaceutical applications.

Formula: C₆H₁₀O₄

InChI: InChI=1/C6H10O4/c7-3-1-9-6-4(8)2-10-5(3)6/h3-8H,1-2H2/t3-,4-,5+,6+/m1/s1

InChI key: InChIKey=KLDXJTOLSGUMSJ-JGWLITMVSA-N

SMILES: O[C@@H]1[C@@]2([C@@]([C@H](O)CO2)(OC1)[H])[H]

Synonyms:

• (+)-<span class="text-smallcaps">D</span>-Isosorbide
• 1,4:3,6-Dianhydro-<span class="text-smallcaps">D</span>-glucitol
• 1,4:3,6-Dianhydro-<span class="text-smallcaps">D</span>-sorbitol
• 1,4:3,6-Dianhydro-D-glucitol
• 1,4:3,6-Dianhydro-D-sorbitol
• 1,4:3,6-Dianhydrosorbitol
• 1,4:3,6-Dianhydrosorbitol 2,5-dinitrate
• 1,4:3,6-dianhydro-D-altritol
• 1,4:3,6-dianhydro-D-iditol
• 1,4:3,6-dianhydro-L-glucitol
• <span class="text-smallcaps">D</span>-Glucitol, 1,4:3,6-dianhydro-
• Addolink 0312
• At 101
• Devicoran
• Dianhydro-D-glucitol
• Furo[3,2-b]furan, <span class="text-smallcaps">D</span>-glucitol deriv.
• Glucitol, 1,4:3,6-dianhydro-, <span class="text-smallcaps">D</span>-
• Hydronol
• Ismotic
• Isobide
• Isosorbitol
• NSC 40725
• Novasorb
• Novosorb P
• Polysorb
• Polysorb B
• Polysorb P
• Polysorb PB
• Polysorb PBA
• Polysorb PS
• Sorbitol, 1,4:3,6-dianhydro-
• Furo[3,2-b]furan, D-glucitol deriv.
• Glucitol, 1,4:3,6-dianhydro-, D-
• D-Glucitol, 1,4:3,6-dianhydro-
• (3S,3AR,6R,6AR)-HEXAHYDRO-FURO[3,2-B]FURAN-3,6-DIOL
• 1,4:3,6-DIANHYDROGLUCITOL
• 4:3,6-dianhydro-d-glucito
• ISOSORBIDE
• DIANHYDRO-D-SORBITOL
• d-1,4:3,6-dianhydroglucitol
• 1,4:3,6-dianhydro-d-glucito
• Isosorbide,typically98%
• D-ISOSORBIDE
• Isosorbid
• D-Glucitol, 1,4:3,6-dianhydro-(9CI)

Isosorbide

CAS: 652-67-5

Formula: C₆H₁₀O₄

Purity: >98.0%(GC)

Color and Shape: White to Orange to Green powder to crystal

Molecular weight: 146.14

Ref: 3B-I0407

D-Isosorbide, 98%

CAS: 652-67-5

D-Isosorbide is used as a reagent in the preparation of detergents, agrochemicals, cleansers, cosmetics and vasodilators. It is also employed as a pharmaceutical intermediate for dimethyl ether and mono- and dinitrate derivatives, which is used as vasodilators and coronary disease therapeutics. It i

Formula: C₆H₁₀O₄

Purity: 98%

Color and Shape: White to cream to pale yellow, Crystals or powder or crystalline powder or fused solid or flakes

Molecular weight: 146.14

Ref: 02-A13989

Isosorbide

CAS: 652-67-5

Heterocyclic compounds with oxygen hetero-atom(s) only, nesoi

Formula: C₆H₁₀O₄

Purity: 75%

Color and Shape: Colorless Light Yellow Liquid

Molecular weight: 146.05791

Ref: 45-1352008

Isosorbide

CAS: 652-67-5

Formula: C₆H₁₀O₄

Purity: 96%

Color and Shape: Solid

Molecular weight: 146.1412

Ref: IN-DA003R5L

Isosorbide

CAS: 652-67-5

Isosorbide

Purity: ≥95%

Molecular weight: 146.14g/mol

Ref: 54-BUP19816

Isosorbide

CAS: 652-67-5

Isosorbide

Purity: 98%

Molecular weight: 146.14g/mol

Ref: 54-OR1028004

Isosorbide

CAS: 652-67-5

Formula: C₆H₁₀O₄

Color and Shape: Yellow Liquid

Molecular weight: 146.14

Ref: 4Z-I-197

Isosorbide

CAS: 652-67-5

Formula: C₆H₁₀O₄

Color and Shape: Neat

Molecular weight: 146.14

Ref: 04-C14475300

Isosorbide

Controlled Product

CAS: 652-67-5

Formula: C₆H₁₀O₄

Color and Shape: Neat

Molecular weight: 146.14

Ref: 86-MM0126.03

Isosorbide

CAS: 652-67-5

Isosorbide (Devicoran) is a heterocyclic compound that is derived from glucose, used as a diuretic.

Formula: C₆H₁₀O₄

Purity: 97.28%

Color and Shape: Crystals Solid

Molecular weight: 146.14

Ref: TM-T6551

Isosorbide-d4

CAS: 652-67-5

Formula: C₆H₆D₄O₄

Molecular weight: 150.17

Ref: 4Z-I-198

1,4:3,6-Dianhydro-D-glucitol

CAS: 652-67-5

Formula: C₆H₁₀O₄

Molecular weight: 146.14

Ref: 7W-GC7939

Isosorbide

CAS: 652-67-5

Applications Reagent used to prepare detergents, cleansers, cosmetics, agrochemicals and vasodilators.
References Hastwell, P., et al.: Mutagen., 24, 455 (2009), Guillarme, S., et al.: Bioorg. Chem., 38, 43 (2010), Dillon, G., et al.: Bioorg. Med. Chem., 18, 1045 (2010),

Formula: C₆H₁₀O₄

Color and Shape: Neat

Molecular weight: 146.14

Ref: TR-I901680

Isosorbide

CAS: 652-67-5

Formula: C₆H₁₀O₄

Molecular weight: 146.14

Ref: ST-EA-CP-I24003

1,4:3,6-Dianhydro-D-glucitol

CAS: 652-67-5

Isosorbide dinitrate is a drug that belongs to the class of nitrates. It is used in the treatment of angina pectoris, as well as congestive heart failure and chronic heart failure. Isosorbide dinitrate has been shown to cause caspase-independent cell death in human leukemia cells and breast cancer cells. This may be due to its ability to inhibit mitochondrial membrane potential and interfere with intracellular calcium mobilization. The optimum concentration for isosorbide dinitrate is 10 µM, which inhibits the growth of bacteria, including Mycobacterium tuberculosis and Salmonella enterica serovar Typhimurium. The drug also inhibits the production of proinflammatory cytokines such as IL-1β, IL-6, and TNF-α by inhibiting c-jun phosphorylation. Isosorbide dinitrate also has anti-inflammatory properties, which may be due to its ability to inhibit 4-hyd

Formula: C₆H₁₀O₄

Purity: (%) Min. 98%

Color and Shape: White Off-White Powder

Molecular weight: 146.14 g/mol

Ref: 3D-MD07153

(3R,3aR,6S,6aR)-Hexahydrofuro[3,2-b]furan-3,6-diol

CAS: 652-67-5

Formula: C₆H₁₀O₄

Purity: 96%

Color and Shape: Solid, White - Pale yellow powder

Molecular weight: 146.142

Ref: 10-F242232

Isosorbide-D8

Controlled Product

CAS: 652-67-5

Formula: C₆H₂D₈O₄

Color and Shape: Off-White

Molecular weight: 154.19

Ref: TR-I902153