CAS 65243-33-6

Cefetamet pivoxil

Description:

Cefetamet pivoxil is a semi-synthetic cephalosporin antibiotic, primarily used for its antibacterial properties. It is characterized by its broad-spectrum activity against various Gram-positive and Gram-negative bacteria, making it effective in treating respiratory tract infections, urinary tract infections, and skin infections. The compound is a prodrug, meaning it is converted into its active form, cefetamet, after administration. Cefetamet pivoxil is typically administered orally and is known for its favorable pharmacokinetic profile, including good absorption and distribution in the body. Its mechanism of action involves inhibiting bacterial cell wall synthesis, which ultimately leads to cell lysis and death. The substance is generally well-tolerated, but like all antibiotics, it may cause side effects such as gastrointestinal disturbances or allergic reactions in some individuals. As with any antibiotic, appropriate use is crucial to prevent the development of antibiotic resistance. Overall, cefetamet pivoxil represents an important option in the arsenal of antimicrobial therapies.

Formula: C₂₀H₂₅N₅O₇S₂

InChI: InChI=1/C20H25N5O7S2/c1-9-6-33-16-12(23-14(26)11(24-30-5)10-7-34-19(21)22-10)15(27)25(16)13(9)17(28)31-8-32-18(29)20(2,3)4/h7,12,16H,6,8H2,1-5H3,(H2,21,22)(H,23,26)/b24-11-/t12-,16-/m1/s1

InChI key: InChIKey=DASYMCLQENWCJG-XUKDPADISA-N

SMILES: C(OCOC(C(C)(C)C)=O)(=O)C=1N2[C@@]([C@H](NC(/C(=N\OC)/C=3N=C(N)SC3)=O)C2=O)(SCC1C)[H]

Synonyms:

• (2,2-Dimethyl-1-oxopropoxy)methyl (6R,7R)-7-[[(2Z)-2-(2-amino-4-thiazolyl)-2-(methoxyimino)acetyl]amino]-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
• (6R,7R)-7-[[(2-Amino-4-thiazolyl)(methoxyimino)acetyl]amino]-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid (2,2-dimethyl-1-oxopropoxy)methyl ester
• 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[(2-amino-4-thiazolyl)(methoxyimino)acetyl]amino]-3-methyl-8-oxo-, (2,2-dimethyl-1-oxopropoxy)methyl ester, [6R-[6α,7β(Z)]]-
• 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[(2Z)-(2-amino-4-thiazolyl)(methoxyimino)acetyl]amino]-3-methyl-8-oxo-, (2,2-dimethyl-1-oxopropoxy)methyl ester, (6R,7R)-
• 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[(2Z)-2-(2-amino-4-thiazolyl)-2-(methoxyimino)acetyl]amino]-3-methyl-8-oxo-, (2,2-dimethyl-1-oxopropoxy)methyl ester, (6R,7R)-
• Cefetamet pivoxil
• Ceftamet pivoxil
• [(2,2-dimethylpropanoyl)oxy]methyl (6R,7R)-7-{[(2E)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino}-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
• [(2,2-dimethylpropanoyl)oxy]methyl (6R,7R)-7-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino}-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
• -8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid
• CEFETAMET PIVOXIL HCL
• cefetamet pivoxyl
• (6R,7R)-7-[[(2Z)-2-(2-AMino-4-thiazolyl)-2-(MethoxyiMino)acetyl]aMino]-3-Methyl
• (6R,7R)-7-[[2-(2-Amino-4-thiazolyl)-2-[(Z)-methoxyimino]acetyl]amino]-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]octa-2-ene-2-carboxylic acid pivaloyloxymethyl ester
• cefetamet ouvixuk hydrochloride
• Cefetamet Pivoxil hdyrochloride
• Cefetamet pivoxyl USP/EP/BP
• (6R,7R)-7-[[(Z)-2-(2-Aminothiazol-4-yl)-2-(methoxyimino)acetyl]amino]-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid (2,2-dimethyl-1-oxopropoxy)methyl ester
• CefetaMet pivoxyl Hydrochloride
• Cefditoren iMpurity 3, CefetaMet Pivoxil
• CEFERAMETPIVOXYL

Cefetamet Pivoxil

CAS: 65243-33-6

Formula: C₂₀H₂₅N₅O₇S₂

Color and Shape: Pale Yellow Solid

Molecular weight: 511.57

Ref: 4Z-C-881

Cefetamet pivoxil

CAS: 65243-33-6

Formula: C₁₄H₁₅N₅O₅S₂

Molecular weight: 397.43

Ref: 7W-GA9859

Cefetamet Pivoxil

Controlled Product

CAS: 65243-33-6

Applications Third generation cephalosporin antibiotics. Antibacterial.
References Thomas, M.G., et al.: Antimicrob. Agents Chemother., 29, 945 (1986), Seiler, J., et al.: Toxicol. Lett., 131, 105 (2002), Escher, B., et al.: Environ. Sci. Technol., 39, 3090 (2005),

Formula: C₂₀H₂₅N₅O₇S₂

Color and Shape: Light Yellow

Molecular weight: 511.57

Ref: TR-C242780

Cefetamet pivoxyl

CAS: 65243-33-6

Cefetamet pivoxyl is a cephalosporin antibiotic and has bactericidal activity against many gram-positive and gram-negative bacteria. It binds to the 50S ribosomal subunit by inhibiting protein synthesis. Cefetamet pivoxyl is effective in the treatment of urinary infections, acute maxillary sinusitis, chronic bronchitis, and other infectious diseases caused by susceptible germs. The drug is also used as an antimicrobial agent for prophylaxis during surgery, especially in the case of high risk patients or those who have been exposed to infections. Cefetamet pivoxyl can be administered orally or intravenously and exhibits bactericidal activity against many gram-positive and gram-negative bacteria. It binds to the 50S ribosomal subunit by inhibiting protein synthesis. Cefetamet pivoxyl is effective in the treatment of urinary infections, acute maxillary sinusitis, chronic bronchitis

Purity: Min. 95%

Ref: 3D-FC44060

Cefetamet pivoxyl

CAS: 65243-33-6

Cefetamet pivoxyl, a cephalosporin antibiotic, effectively inhibits 355 enteropathogens, including Gram-negative bacteria (ausgenommen Pseudomonas aeruginosa) and Legionella pneumophila [1].

Formula: C₂₀H₂₅N₅O₇S₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 511.57

Ref: TM-T78537