CAS 653-63-4

dAMP

Description:

The chemical substance known as dAMP, or deoxyadenosine monophosphate, is a nucleotide that plays a crucial role in the biochemistry of nucleic acids. It is a building block of DNA, consisting of a deoxyribose sugar, a phosphate group, and an adenine base. The CAS number 653-63-4 uniquely identifies this compound in chemical databases. dAMP is involved in various biological processes, including DNA synthesis and repair, as it serves as a precursor for the synthesis of deoxyadenosine triphosphate (dATP), which is essential for DNA replication. In terms of its physical properties, dAMP is typically a white to off-white powder that is soluble in water, reflecting its polar nature due to the phosphate group. Its stability can be influenced by factors such as pH and temperature, and it is sensitive to hydrolysis. In laboratory settings, dAMP is utilized in molecular biology applications, including PCR and other DNA manipulation techniques, highlighting its importance in genetic research and biotechnology.

Formula: C₁₀H₁₄N₅O₆P

InChI: InChI=1S/C10H14N5O6P/c11-9-8-10(13-3-12-9)15(4-14-8)7-1-5(16)6(21-7)2-20-22(17,18)19/h3-7,16H,1-2H2,(H2,11,12,13)(H2,17,18,19)/t5-,6+,7+/m0/s1

InChI key: InChIKey=KHWCHTKSEGGWEX-RRKCRQDMSA-N

SMILES: NC1=C2C(N(C=N2)[C@@H]3O[C@H](COP(=O)(O)O)[C@@H](O)C3)=NC=N1

Synonyms:

• 2'-Deoxy-5'-O-phosphonatoadenosine
• 2'-Deoxyadenosine 5'-monophosphate
• 2'-deoxy-Adenosine 5'-phosphorate
• 5'-Adenylic Acid, 2'-Deoxy-, Ion(2-)
• dAMP.H2
• 2'-Deoxyadenosine 5'-Phosphate
• 2'-Deoxy-5'-adenylic acid
• 2'-Deoxy-5'-AMP
• 2'-Deoxyadenosine monophosphate
• 2'-Deoxyadenylic acid
• 2'-Deoxy-AMP
• 2'-Desoxyadenosin-5'-(dihydrogenphosphat)
• 5'-Adenylic acid, 2'-deoxy-
• 5'-dAMP
• 5'-Dihidrogenofosfato De 2'-Desoxiadenosina
• 5'-Dihydrogenophosphate De 2'-Desoxyadenosine
• Adenosine, 2'-deoxy-, 5'-(dihydrogen phosphate)
• dAMP
• Deoxyadenosine 5'-monophosphate
• Deoxyadenosine 5'-phosphate
• Deoxyadenosine monophosphate
• Deoxyadenylic acid
• Deoxy-AMP
• Nsc 77680
• Nsc 82625

2'-Deoxyadenosine-5'-monophosphate, 98%

CAS: 653-63-4

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Formula: C₁₀H₁₄N₅O₆P

Purity: 98%

Molecular weight: 331.22

Ref: 02-J64402

5'-Adenylic acid, 2'-deoxy-

CAS: 653-63-4

Formula: C₁₀H₁₄N₅O₆P

Purity: 95%

Color and Shape: Solid

Molecular weight: 331.2218

Ref: IN-DA00IBHB

2'-Deoxyadenosine 5'-monophosphate

CAS: 653-63-4

2'-Deoxyadenosine 5'-monophosphate

Purity: 98%

Molecular weight: 331.22g/mol

Ref: 54-OR1027552

2''-Deoxyadenosine-5''-monophosphate

CAS: 653-63-4

Formula: C₁₀H₁₄N₅O₆P

Molecular weight: 331.22

Ref: 7W-GE6112

2'-Deoxyadenosine-5'-monophosphate

CAS: 653-63-4

2'-Deoxyadenosine-5'-monophosphate

Purity: ≥98%

Molecular weight: 331.22g/mol

Ref: 54-BUP14703

2'-Deoxyadenosine-5'-monophosphate

CAS: 653-63-4

2'-Deoxyadenosine-5'-monophosphate (D-AMP) is a nucleoside comprised of adenine attached to a ribose (ribofuranose) moiety via a -N9-glycosidic bond.

Formula: C₁₀H₁₄N₅O₆P

Purity: 98% - 99.83%

Color and Shape: Solid

Molecular weight: 331.22

Ref: TM-T4737

2’-Deoxyadenosine 5’Monophosphate

Controlled Product

CAS: 653-63-4

Applications 2’-Deoxyadenosine 5’Monophosphate is the first nucleotide of the phi 29 DNA.
References Shih, M.F., et. al.: Virology, 133, 56 (1984)

Formula: C₁₀H₁₄N₅O₆P

Color and Shape: Neat

Molecular weight: 331.222

Ref: TR-D231630

2'-Deoxyadenosine-5'-monophosphate free acid

CAS: 653-63-4

2'-Deoxyadenosine-5'-monophosphate free acid (2DAMP) is a nucleoside analogue that can be used as a fluorescent probe for detecting water vapor. 2DAMP has been shown to have cytotoxic activity against solid tumours in vitro, and may act by hydrogen bonding interactions with the active site of the enzyme form. 2DAMP is also an important cofactor in the polymerase chain reaction, and can inhibit cellular proliferation by inhibiting nuclear DNA synthesis. This drug has been used as an active antiretroviral therapy, where it inhibits HIV-1 reverse transcriptase. 2DAMP's mechanism of action involves the inhibition of p-nitrophenyl phosphate reductase (PNPPR), which is responsible for converting p-nitrophenyl phosphate into p-nitrophenol.

Formula: C₁₀H₁₄N₅O₆P

Purity: Min. 95%

Color and Shape: White Powder

Molecular weight: 331.23 g/mol

Ref: 3D-ND05971

2′-Deoxyadenosine-5′-monophosphate

CAS: 653-63-4

Formula: C₁₀H₁₄N₅O₆P

Purity: 95%

Color and Shape: Solid

Molecular weight: 331.225

Ref: 10-F236817