CAS 65307-12-2

Cefetrizole

Description:

Cefetrizole is a synthetic antibiotic belonging to the class of cephalosporins, which are characterized by their beta-lactam structure. It is primarily used for its antibacterial properties, effective against a range of Gram-positive and Gram-negative bacteria. Cefetrizole works by inhibiting bacterial cell wall synthesis, leading to cell lysis and death. The compound is typically administered via injection and is known for its stability against certain beta-lactamases, which are enzymes produced by some bacteria to resist antibiotic action. Its pharmacokinetics involve absorption, distribution, metabolism, and excretion, with a focus on achieving effective therapeutic concentrations in the body. Common side effects may include allergic reactions, gastrointestinal disturbances, and potential impacts on renal function. As with other antibiotics, the use of cefetrizole should be guided by susceptibility testing to ensure effectiveness and minimize the risk of resistance development. Overall, cefetrizole represents an important option in the treatment of bacterial infections, particularly in settings where resistance to other antibiotics is a concern.

Formula: C₁₆H₁₅N₅O₄S₃

InChI: InChI=1/C16H15N5O4S3/c22-10(4-9-2-1-3-26-9)19-11-13(23)21-12(15(24)25)8(5-27-14(11)21)6-28-16-17-7-18-20-16/h1-3,7,11,14H,4-6H2,(H,19,22)(H,24,25)(H,17,18,20)/t11-,14-/m1/s1

SMILES: c1cc(CC(=N[C@@H]2C(=O)N3C(=C(CS[C@H]23)CSc2nc[nH]n2)C(=O)O)O)sc1

Synonyms:

• Cefetrizole [INN]
• (6R,7R)-8-Oxo-7-(2-(2-thienyl)acetamido)-3-((s-triazol-3-ylthio)methyl)-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid
• Cefetrizolum
• Unii-61K37E446T
• (6R,7R)-8-Oxo-7-(2-(2-thienyl)acetamido)-3-((s-triazol-3-ylthio)methyl)-5-thia-1-azabicyclo(4.2.0)oct-2-en-2-carboxylic acid.
• (6R,7R)-8-oxo-7-[(thiophen-2-ylacetyl)amino]-3-[(1H-1,2,4-triazol-5-ylsulfanyl)methyl]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid

Cefetrizole

CAS: 65307-12-2

Ref: 7W-GA7103

Cefetrizole

CAS: 65307-12-2

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Formula: C₁₆H₁₅N₅O₄S₃

Purity: Min. 95%

Molecular weight: 437.5 g/mol

Ref: 3D-QCA30712

Cefetrizole

CAS: 65307-12-2

Ceftezole is an α-Glucosidase inhibitor (IC50: 2.1 μM; Ki: 0.578 μM).

Formula: C₁₆H₁₅N₅O₄S₃

Purity: 98%

Color and Shape: Solid

Molecular weight: 437.52

Ref: TM-T10751