CAS 6533-00-2
:Norgestrel
Description:
Norgestrel is a synthetic progestin, primarily used in hormonal contraceptives and hormone replacement therapies. It is characterized by its ability to mimic the natural hormone progesterone, thereby influencing various physiological processes. Norgestrel is known for its effectiveness in preventing ovulation, altering the menstrual cycle, and providing endometrial protection. The compound is typically administered in oral form, often in combination with estrogen in contraceptive pills. Chemically, Norgestrel is a derivative of testosterone, featuring a modified steroid structure that enhances its progestational activity while minimizing androgenic effects. It is lipophilic, allowing for good absorption and distribution in the body. The substance is metabolized in the liver, and its pharmacokinetics can be influenced by factors such as age, weight, and concurrent medications. As with any hormonal treatment, potential side effects may include changes in mood, weight fluctuations, and alterations in menstrual patterns. Overall, Norgestrel plays a significant role in reproductive health, providing effective options for contraception and menstrual regulation.
Formula:C21H28O2
InChI:InChI=1/C21H28O2/c1-3-20-11-9-17-16-8-6-15(22)13-14(16)5-7-18(17)19(20)10-12-21(20,23)4-2/h2,13,16-19,23H,3,5-12H2,1H3/t16-,17+,18+,19-,20-,21-/s2
InChI key:InChIKey=WWYNJERNGUHSAO-PYYZKRFANA-N
SMILES:C(C)[C@@]12[C@]([C@]3([C@](CC1)([C@@]4(C(CC3)=CC(=O)CC4)[H])[H])[H])(CC[C@]2(C#C)O)[H]
Synonyms:- (.+-.)-13-Ethyl-17α-ethynyl-17-hydroxygon-4-en-3-one
- (.+-.)-17α-Ethynyl-13-ethyl-17-hydroxygon-4-en-3-one
- (.+-.)-17α-Ethynyl-13β-ethylgon-4-en-17β-ol-3-one
- (.+-.)-Norgestrel
- (17α)-(±)-13-Ethyl-17-hydroxy-18,19-dinorpregn-4-en-20-yn-3-one
- 13-Ethyl-17α-ethynyl-17β-hydroxy-4-gonen-3-one
- 18,19-Dinor-17α-pregn-4-en-20-yn-3-one, 13-ethyl-17-hydroxy-, (.+-.)-
- <span class="text-smallcaps">DL</span>-Norgestrel
- DL-Norgestrel
- Fh 122A
- Methylnorethindrone
- Monovar
- Neogest
- Ovrette
- Postinor
- Sh 70850
- Sh 850
- Wy 3707
- dl-11β-Ethyl-17α-ethynyl-17β-hydroxygon-4-en-3-one
- dl-13-β-Ethyl-17-α-ethynyl-17-β-hydroxygon-4-en-3-one
- α-Norgestrel
- 13-ethyl-17-ethynyl-17-hydroxy-1,2,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-3H-cyclopenta[a]phenanthren-3-one (non-preferred name)
- Norgestrel [USAN:INN:BAN:JAN]
- 18,19-Dinorpregn-4-en-20-yn-3-one, 13-ethyl-17-hydroxy-,(17alpha)-(+-)-
- Norgestrel (DL-)
- (8R,9S,10R,13S,14S)-13-ethyl-17-ethynyl-17-hydroxy-1,2,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-3H-cyclopenta[a]phenanthren-3-one (non-preferred name)
- (+-)-13-Ethyl-17-hydroxy-18,19-dinor-17alpha-pregn-4-en-20-yn-3-one
- dl-13-beta-Ethyl-17-alpha-ethynyl-19-nortestosterone
- 18,19-Dinor-17-alpha-pregn-4-en-20-yn-3-one, 13-ethyl-17-hydroxy-, (+-)-
- 18,19-Dinorpregn-4-en-20-yn-3-one, 13-ethyl-17-hydroxy-, (17α)-(±)-
- (8R,9S,10R,13S,14S,17R)-13-ethyl-17-ethynyl-17-hydroxy-1,2,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-3H-cyclopenta[a]phenanthren-3-one (non-preferred name)
- dl-13-beta-Ethyl-17-alpha-ethynyl-17-beta-hydroxygon-4-en-3-one
- See more synonyms
Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
Found 15 products.
NORGESTREL CRS
CAS:NORGESTREL CRSFormula:C21H28O2Color and Shape:Crystalline Powder. White. Powder.Molecular weight:312.4458Norgestrel
CAS:Estrogens and progestinsFormula:C21H28O2Color and Shape:White Off-White Crystalline PowderMolecular weight:312.20893(±)-13-Ethyl-17α-ethynyl-17-hydroxygon-4-en-3-one
CAS:Formula:C21H28O2Purity:99%Color and Shape:SolidMolecular weight:312.4458Norgestrel
CAS:<p>Norgestrel (WY-3707), a synthetic progestin, is used for contraception and hinders LH/FSH, thickens mucus, and slows ova transit.</p>Formula:C21H28O2Purity:99.71% - 99.72%Color and Shape:Crystals From Methanol White Crystalline PowderMolecular weight:312.45Norgestrel
CAS:Controlled Product<p>Applications Norgestrel is an excellent progestational and ovulation inhibiting steroid. The bioactive enantiomer is levorotatory. Progestogen; oral contraceptive.<br>References Sopirak, A.M., et al.: Anal. Profiles Drug Subs., 4, 294 (1975), Dunson, T.R., et al.: Contraception, 48, 109 (1993),<br></p>Formula:C21H28O2Color and Shape:White To Off-WhiteMolecular weight:312.45Norgestrel-d6 (Major)
CAS:Controlled Product<p>Applications Labelled Norgestrel. It is an excellent progestational and ovulation inhibiting steroid. The bioactive enantiomer is levorotatory. Progestogen; oral contraceptive.<br>References Sopirak, A.M., et al.: Anal. Profiles Drug Subs., 4, 294 (1975), Dunson, T.R., et al.: Contraception, 48, 109 (1993),<br></p>Formula:C21H22D6O2Color and Shape:White To Light YellowMolecular weight:318.49Norgestrel
CAS:Controlled Product<p>Norgestrel is a synthetic progestin that is used in hormonal contraceptives. It is also used to treat endometriosis, uterine bleeding, and other conditions. Norgestrel has been found to bind to the progesterone receptor and inhibit the secretion of luteinizing hormone (LH), follicle-stimulating hormone (FSH), and thyroid-stimulating hormone (TSH). This drug also inhibits hepatic lipase activity and may reduce body mass index by increasing lipid metabolism. Basic fibroblasts incubated with nomegestrol acetate show an increased production of leukemia inhibitory factor (LIF) and neurotrophic factors that are important for cell growth and differentiation. These effects have not been seen in women using this drug for contraception, but have been observed in untreated groups of women.br><br>Norgestrel is a steroidal progestin which has been shown to increase the number of leukocytes in the uterus, particularly</p>Formula:C21H28O2Purity:Min. 95%Molecular weight:312.45 g/mol
