CAS 6538-02-9

(3beta,5alpha)-ergostan-3-ol

Description:

(3beta,5alpha)-ergostan-3-ol, commonly known as ergosterol, is a sterol compound primarily found in fungi, yeast, and some plants. It plays a crucial role in maintaining cell membrane integrity and fluidity, similar to cholesterol in animal cells. Ergosterol is characterized by its tetracyclic structure, which includes a hydroxyl group at the C-3 position and a double bond between C-5 and C-6. This compound is also a precursor to vitamin D2 when exposed to ultraviolet light, highlighting its importance in both nutrition and biochemistry. Ergosterol is often used in laboratory settings for its antifungal properties and as a biomarker for fungal contamination in various products. Its solubility in organic solvents and limited solubility in water are notable physical properties, making it relevant in various biochemical applications. Additionally, ergosterol's presence in the cell membranes of fungi makes it a target for antifungal drugs, which can disrupt its function and lead to cell death.

Formula: C₂₈H₅₀O

InChI: InChI=1/C28H50O/c1-18(2)19(3)7-8-20(4)24-11-12-25-23-10-9-21-17-22(29)13-15-27(21,5)26(23)14-16-28(24,25)6/h18-26,29H,7-17H2,1-6H3/t19-,20+,21-,22-,23-,24+,25-,26-,27-,28+/m0/s1

Synonyms:

• (3b,5a)-Ergostan-3-ol
• 5alpha-Ergostan-3beta-ol
• 6538-02-9
• Ergostan-3-Ol, (3Beta,5Alpha)-
• (3beta,5alpha)-Ergostan-3-ol

Ergostanol

CAS: 6538-02-9

Formula: C₂₈H₅₀O

Molecular weight: 402.71

Ref: 4Z-E-089001

(24S)-Campestanol

Controlled Product

CAS: 6538-02-9

Applications A phytosterol content in plant food which showed hypocholesterolemic and hypotriglyceridemic effects in hypercholesterolemic overweight volunteers. Used in the treatment of metabolic disorders.
References Kasamo, K., et al.: Plant Physiol., 93, 1049 (1990), Davey, M., et al.: J. Sci. Food Agric., 80, 825 (2000), Nomura, T., et al.: J. Biol. Chem., 280, 17873 (2005), Matos, L., et al.: Food Chem., 102, 406 (2007),

Formula: C₂₈H₅₀O

Color and Shape: Neat

Molecular weight: 402.70

Ref: TR-C155300

Ergostanol

Controlled Product

CAS: 6538-02-9

Ergostanol is a fungal biomass that is used as a dietary supplement and functional sweetener. It is produced by the fungus Aspergillus niger in the form of micron-sized particles. Ergostanol inhibits cholesterol synthesis by suppressing 3-hydroxy-3-methylglutaryl coenzyme A reductase (HMGCR) activity, which is an enzyme that catalyzes the conversion of HMGCR to mevalonate. Ergostanol has also been shown to inhibit fatty acid synthesis, reducing the production of fatty acids and triglycerides. This inhibition may be due to its ability to bind with hydroxyl groups on fatty acids, causing a decrease in their concentrations.

Formula: C₂₈H₅₀O

Purity: 95%Min

Color and Shape: Powder

Molecular weight: 402.7 g/mol

Ref: 3D-FE145370