CAS 65391-42-6

L-Leucine, N-[(2S,3R)-3-amino-2-hydroxy-1-oxo-4-phenylbutyl]-, hydrochloride (1:1)

Description:

L-Leucine, N-[(2S,3R)-3-amino-2-hydroxy-1-oxo-4-phenylbutyl]-, hydrochloride (1:1), with CAS number 65391-42-6, is a synthetic amino acid derivative that combines the properties of L-leucine, an essential branched-chain amino acid, with a specific side chain structure. This compound is characterized by its role in protein synthesis and its potential applications in biochemistry and pharmacology. The presence of the hydrochloride indicates that it is a salt form, which enhances its solubility in water, making it suitable for various formulations. The stereochemistry, denoted by the (2S,3R) configuration, suggests specific spatial arrangements that can influence its biological activity and interaction with receptors or enzymes. As a hydrochloride salt, it typically exhibits improved stability and bioavailability compared to its free base form. Overall, this compound is of interest in research related to metabolic pathways, muscle synthesis, and potential therapeutic applications in conditions requiring amino acid supplementation.

Formula: C₁₆H₂₄N₂O₄·ClH

InChI: InChI=1S/C16H24N2O4.ClH/c1-10(2)8-13(16(21)22)18-15(20)14(19)12(17)9-11-6-4-3-5-7-11;/h3-7,10,12-14,19H,8-9,17H2,1-2H3,(H,18,20)(H,21,22);1H/t12-,13+,14+;/m1./s1

InChI key: InChIKey=XGDFITZJGKUSDK-UDYGKFQRSA-N

SMILES: C([C@H]([C@@H](C(N[C@@H](CC(C)C)C(O)=O)=O)O)N)C1=CC=CC=C1.Cl

Synonyms:

• L-Leucine, N-(3-amino-2-hydroxy-1-oxo-4-phenylbutyl)-, monohydrochloride, [S-(R*,S*)]-
• Bestatin hydrochloride
• L-Leucine, N-[(2S,3R)-3-amino-2-hydroxy-1-oxo-4-phenylbutyl]-, hydrochloride (1:1)
• L-Leucine, N-[(2S,3R)-3-amino-2-hydroxy-1-oxo-4-phenylbutyl]-, monohydrochloride
• (-)-Bestatin hydrochloride

Bestatin hydrochloride, 98%

CAS: 65391-42-6

Bestatin is an inhibitor of amino peptidases and a potent, irreversible inhibitor of LTA4 hydrolase. It inhibits the amino peptidase activity of LTA4 hydrolase with a Ki value of 201 nM. It offers promise as a novel analgesic because it protects endogenous opioid peptides against degradation. It doe

Formula: C₁₆H₂₅ClN₂O₄

Purity: 98%

Color and Shape: Powder

Molecular weight: 344.84

Ref: 02-J60384

Bestatin hydrochloride

CAS: 65391-42-6

Formula: C₁₆H₂₅ClN₂O₄

Purity: 98%

Color and Shape: Solid

Molecular weight: 344.8337

Ref: IN-DA003O5U

Bestatin hydrochloride

CAS: 65391-42-6

Bestatin hydrochloride

Purity: ≥98%

Molecular weight: 344.84g/mol

Ref: 54-BUP17148

Bestatin hydrochloride

CAS: 65391-42-6

Formula: C₁₆H₂₄N₂O₄·HCl

Purity: ≥ 98.0% (dried basis)

Color and Shape: White to almost white powder

Molecular weight: 344.87

Ref: 7W-GA7849

Bestatin-d7 HCl (Ubenimex-d7 HCl)

CAS: 65391-42-6

Formula: C₁₆H₁₇D₇N₂O₄·HCl

Color and Shape: White To Off-White Solid

Molecular weight: 315.42 36.46

Ref: 4Z-B-119003

Bestatin hydrochloride

CAS: 65391-42-6

Bestatin hydrochloride

Formula: C₁₆H₂₄N₂O₄·ClH

Purity: By hplc: >98.5% by area (Typical Value in Batch COA)

Color and Shape: White Solid

Molecular weight: 344.83g/mol

Ref: 54-BIMI2137

Ubenimex Hydrochloride [for Biochemical Research]

CAS: 58970-76-6, 65391-42-6

Formula: C₁₆H₂₄N₂O₄·HCl

Purity: >97.0%(HPLC)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 344.84

Ref: 3B-B4000

Bestatin hydrochloride

CAS: 65391-42-6

Bestatin hydrochloride (Ubenimex hydrochloride) is an inhibitor of aminopeptidase N (APN)/CD13 and aminopeptidase B.

Formula: C₁₆H₂₅ClN₂O₄

Purity: 98% - 99.93%

Color and Shape: Solid

Molecular weight: 344.84

Ref: TM-T3529

Ubenimex (Bestatin) HCl Salt

CAS: 65391-42-6

Ubenimex is a peptide-based inhibitor of aminopeptidase enzymes that act on the N-terminus of amino acid chains. It is also an inhibitor of Leucine aminopeptidase 3 (LAP3) and a potent irreversible inhibitor of Leukotriene A4 (LTA4) hydrolase. It is used in the treatment of non-alcoholic steatohepatitis. Ubenimex binds to the active site of aminopeptidases and inhibits their activity, thus preventing degradation of peptides. Ubenimex has been shown to inhibit aminopeptidase A and B, but not C or D. As a result, it prevents cleavage of the N-terminal amino acids from proteins, which may be involved in inflammatory processes. Furthermore Bestatin has been shown to exhibit antibacterial properties against P. gingivalis and F. nucleatum and is available in the salt form: Hydrochloride.

Purity: Min. 98%

Molecular weight: 344.84 g/mol

Ref: 3D-UBX-3876-PI

Bestatin HCl - Bio-X ™

CAS: 65391-42-6

Bestatin is a competitive protease inhibitor. It inhibits aminopeptidase N and is being studied for the use and treatment for acute myelocytic leukemia.

Formula: C₁₆H₂₄N₂O₄•HCl

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 344.83 g/mol

Ref: 3D-BB164242

Bestatin hydrochloride

CAS: 65391-42-6

Aminopeptidase inhibitor; analgesic

Formula: C₁₆H₂₄N₂O₄•HCl

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 344.83 g/mol

Ref: 3D-FB29613

(S)-2-((2S,3R)-3-Amino-2-hydroxy-4-phenylbutanamido)-4-methylpentanoic acid hydrochloride

CAS: 65391-42-6

Purity: 98%

Molecular weight: 344.8399963

Ref: 10-F868741