CAS 654059-21-9

Piperidine,3-methyl-1-[[3-methyl-4-(1-methylethyl)-5-oxo-2(5H)-isoxazolyl]carbonyl]-, (3S)-

Description:

Piperidine, 3-methyl-1-[[3-methyl-4-(1-methylethyl)-5-oxo-2(5H)-isoxazolyl]carbonyl]-, (3S)-, identified by CAS number 654059-21-9, is a chemical compound characterized by its piperidine core, which is a six-membered saturated nitrogen-containing heterocycle. The compound features a methyl group at the 3-position of the piperidine ring, contributing to its structural complexity. Additionally, it contains a carbonyl group linked to a 3-methyl-4-(1-methylethyl)-5-oxo-2(5H)-isoxazole moiety, which imparts unique reactivity and potential biological activity. The (3S)- designation indicates the specific stereochemistry at the piperidine's 3-position, which can influence the compound's pharmacological properties. This compound may exhibit various characteristics such as solubility in organic solvents, potential for hydrogen bonding due to the presence of the nitrogen atom, and reactivity typical of carbonyl-containing compounds. Its specific applications and biological activities would depend on further studies and evaluations in medicinal chemistry and pharmacology.

Formula: C₁₄H₂₂N₂O₃

BAY 59-9435

CAS: 654059-21-9

BAY 59-9435 is a highly selective small molecule activator of PPARβ/δ. BAY 59-9435 has been shown to increase mitochondrial biogenesis and fatty acid oxidation in vitro, as well as improve insulin sensitivity in vivo. These effects are mediated by the activation of PPARβ/δ, which is an important regulator of metabolic processes. The activation of PPARβ/δ also decreases inflammatory gene expression such as toll-like receptors, camp levels, and sphingosine kinase. The mechanism by which BAY 59-9435 increases mitochondrial biogenesis may involve upregulation of transcription factor peroxisome proliferator-activated receptor gamma coactivator 1α (PGC1α) and other genes that encode proteins involved in mitochondrial biogenesis.

Formula: C₁₄H₂₂N₂O₃

Purity: Min. 95%

Molecular weight: 266.34 g/mol

Ref: 3D-EBB05921

BAY 59-9435

CAS: 654059-21-9

HSL-IN-2 is a selective inhibitor of Hormone Sensitive Lipase (HSL; IC50: 0.023 μM).

Formula: C₁₄H₂₂N₂O₃

Purity: 98%

Color and Shape: Solid

Molecular weight: 266.34

Ref: TM-T11577