CAS 65473-08-7

(Z)-Naftifine

Controlled Product

CAS: 65473-08-7

Applications (Z)-Naftifine is the Z-isomer of Naftifine (N213100); an antimycotic allylamine and antifungal (topical) agent.
References Georgopoulos, A., et al.: Antimicrob. Ag. Chemother., 19, 386 (1981); Meingassner, J.C., et al.: J. Invest. Dermatol., 77, 444 (1981); Paltauf, F., et al.: Biochim Biophys. Acta, 712, 268 (1982); Aggarwal, D., et al.: J. Pharm. Pharmacol., 56, 1509 (2004)

Formula: C₂₁H₂₁N

Color and Shape: Neat

Molecular weight: 287.40

Ref: TR-N213105

(Z)-Naftifine

CAS: 65473-08-7

(Z)-Naftifine is an antifungal agent, which is a synthetic compound with a unique chemical structure. This compound is derived through chemical synthesis, rather than being isolated from natural sources. Its mode of action involves inhibiting the enzyme squalene epoxidase, a crucial component in the biosynthesis of ergosterol, an essential sterol in fungal cell membranes. This inhibition leads to a deficit in ergosterol, disrupting cell membrane integrity and ultimately causing fungal cell death.

Formula: C₂₁H₂₁N

Purity: Min. 95%

Molecular weight: 287.4 g/mol

Ref: 3D-QCA47308