CAS 655-05-0

Thozalinone

Description:

Thozalinone, with the CAS number 655-05-0, is a chemical compound that belongs to the class of thiazolidinones. It is characterized by its heterocyclic structure, which includes a thiazolidine ring, contributing to its biological activity. Thozalinone is primarily recognized for its use in agricultural applications, particularly as a herbicide. Its mode of action typically involves the inhibition of specific enzymatic pathways in plants, leading to growth disruption. The compound is generally considered to have moderate toxicity to non-target organisms, necessitating careful handling and application. In terms of physical properties, thozalinone is usually a solid at room temperature and may exhibit solubility in organic solvents. Its stability can be influenced by environmental factors such as pH and temperature. As with many agrochemicals, regulatory assessments are essential to evaluate its environmental impact and safety profile. Overall, thozalinone serves as an important tool in crop management, although its use must be balanced with ecological considerations.

Formula: C₁₁H₁₂N₂O₂

InChI: InChI=1S/C11H12N2O2/c1-13(2)11-12-10(14)9(15-11)8-6-4-3-5-7-8/h3-7,9H,1-2H3

InChI key: InChIKey=JJSHYECKYLDYAR-UHFFFAOYSA-N

SMILES: O=C1C(OC(N(C)C)=N1)C2=CC=CC=C2

Synonyms:

• 2-(Dimethylamino)-5-phenyl-1,3-oxazol-4(5H)-one
• 2-(Dimethylamino)-5-phenyl-1,3-oxazol-4-one
• 2-(Dimethylamino)-5-phenyl-2-oxazolin-4-one
• 2-(Dimethylamino)-5-phenyl-4(5H)-oxazolone
• 2-Dimethylamino-5-phenyl-oxazol-4-one
• 2-Oxazolin-4-one, 2- (dimethylamino)-5-phenyl-
• 4(5H)-oxazolone, 2-(dimethylamino)-5-phenyl-
• 5-Phenyl-2-(dimethylamino)-2-oxazolin-4-one
• 655-05-0
• Cl 39808
• NSC 170962
• Stimsen

2-(Dimethylamino)-5-phenyloxazol-4(5H)-one

CAS: 655-05-0

Formula: C₁₁H₁₂N₂O₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 204.2252

Ref: IN-DA006PXN

Thozalinone

CAS: 655-05-0

Thozalinone

Purity: ≥98%

Molecular weight: 204.23g/mol

Ref: 54-BUP13639

Thozalinone

CAS: 655-05-0

Thozalinone is a psychostimulant agent inducing the release of norepinephrine and dopamine.

Formula: C₁₁H₁₂N₂O₂

Purity: 99.68%

Color and Shape: Solid

Molecular weight: 204.23

Ref: TM-T19893

Thozalinone

Controlled Product

CAS: 655-05-0

Applications Thozalinone is a psychostimulant that has been used as an antidepressant. Thozalinone likely acts via inducing the release of norepinephrine and dopamine as with its analogues pemoline and aminorex.
References Greenblatt, E., et al.: Toxicol. Appl. Pharma., 7, 566 (1965); Yen-Koo, H., et al.: Drug and Chem. Toxicol., 3, 237 (1980)

Formula: C₁₁H₁₂N₂O₂

Color and Shape: Neat

Molecular weight: 204.23

Ref: TR-T398000

Thozalinone

CAS: 655-05-0

Purity: 98%

Molecular weight: 204.2290039

Ref: 10-F601148

Thozalinone-d5

Controlled Product

CAS: 655-05-0

Formula: C₁₁D₅H₇N₂O₂

Color and Shape: Neat

Molecular weight: 209.256

Ref: TR-T398002

Thozalinone

CAS: 655-05-0

Thozalinone is a synthetic compound that has been used as an antidepressant treatment for the symptoms of clinical depression. It binds to the CB2 receptor and prevents the reuptake of norepinephrine, which helps to increase levels of this neurotransmitter in the brain. Thozalinone has also shown efficacy in treating inflammatory bowel disease, hepatitis, and bowel diseases. This drug binds to a number of different substrate molecules, such as Toll-like receptor 4 (TLR4), which may be responsible for its ability to suppress inflammation. Thozalinone also acts as a substrate molecule for polymeric matrix metalloproteinases (MMPs), which are involved in tissue remodeling and degradation.

Formula: C₁₁H₁₂N₂O₂

Purity: Min. 95%

Molecular weight: 204.23 g/mol

Ref: 3D-AAA65505