CAS 6554-11-6
:1-(2,5-di-O-tritylpentofuranosyl)pyrimidine-2,4(1H,3H)-dione
Description:
1-(2,5-di-O-tritylpentofuranosyl)pyrimidine-2,4(1H,3H)-dione, with the CAS number 6554-11-6, is a chemical compound that features a pyrimidine ring substituted with a pentofuranosyl moiety. This compound is characterized by its unique structural components, including the presence of two trityl groups, which enhance its stability and solubility. The pyrimidine core contributes to its potential biological activity, as pyrimidines are often found in nucleic acids and various pharmaceuticals. The di-O-trityl modification suggests that the compound may be used in nucleoside chemistry or as a building block in the synthesis of more complex molecules. Its properties may include moderate to high solubility in organic solvents, and it may exhibit specific reactivity patterns typical of pyrimidine derivatives. Additionally, the presence of the furanosyl sugar unit indicates potential interactions with biological targets, making it of interest in medicinal chemistry and biochemistry. Overall, this compound represents a significant structure for research in nucleoside analogs and related fields.
Formula:C47H40N2O6
InChI:InChI=1/C47H40N2O6/c50-41-31-32-49(45(52)48-41)44-43(55-47(37-25-13-4-14-26-37,38-27-15-5-16-28-38)39-29-17-6-18-30-39)42(51)40(54-44)33-53-46(34-19-7-1-8-20-34,35-21-9-2-10-22-35)36-23-11-3-12-24-36/h1-32,40,42-44,51H,33H2,(H,48,50,52)
SMILES:c1ccc(cc1)C(c1ccccc1)(c1ccccc1)OCC1C(C(C(n2ccc(nc2=O)O)O1)OC(c1ccccc1)(c1ccccc1)c1ccccc1)O
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Found 2 products.
2',5'-Bis-O-(triphenylmethyl)uridine
CAS:Nucleosides Derivatives - Protected nucleosides with NH2/OH groupFormula:C47H40N2O6Color and Shape:SolidMolecular weight:728.832',5'-Bis-O-(triphenylmethyl)uridine
CAS:<p>2',5'-Bis-O-(triphenylmethyl)uridine is a synthetic nucleoside that is used in the treatment of leukemia. It is used as an analogue of uridine and guanosine, and is converted to these compounds by decarboxylase enzymes. 2',5'-Bis-O-(triphenylmethyl)uridine has been shown to inhibit the proliferation of L1210 cells in vitro and in vivo, but not normal cells. 2',5'-Bis-O-(triphenylmethyl)uridine also inhibits DNA synthesis by inhibiting the enzyme hydroxylase and carboxylate, which are involved in purine metabolism. This drug binds to the ribonucleotide reductase enzyme and blocks its activity, thereby inhibiting RNA synthesis.</p>Purity:Min. 95%

