CAS 65571-68-8

Lofemizole

Description:

Lofemizole is a chemical compound primarily recognized for its role as a pharmacological agent. It is classified as a selective inhibitor of the enzyme dihydrofolate reductase, which is crucial in the synthesis of folate, an essential vitamin for DNA synthesis and cellular division. This compound is often studied for its potential applications in treating various conditions, including certain types of cancer and autoimmune diseases. Lofemizole exhibits a moderate level of solubility in organic solvents, which can influence its bioavailability and therapeutic efficacy. Its molecular structure features a heterocyclic ring, contributing to its biological activity. Additionally, Lofemizole's pharmacokinetics, including absorption, distribution, metabolism, and excretion, are important factors that determine its clinical use and effectiveness. As with many pharmacological agents, understanding its mechanism of action and potential side effects is crucial for safe and effective application in medical settings. Further research continues to explore its full therapeutic potential and any associated risks.

Formula: C₁₀H₉ClN₂

InChI: InChI=1/C10H9ClN2/c1-7-10(13-6-12-7)8-2-4-9(11)5-3-8/h2-6H,1H3,(H,12,13)

InChI key: InChIKey=MBKWNJVQSFBLQI-UHFFFAOYSA-N

SMILES: CC1=C(NC=N1)C2=CC=C(Cl)C=C2

Synonyms:

• 1H-Imidazole, 4-(4-chlorophenyl)-5-methyl-
• 1H-Imidazole, 5-(4-chlorophenyl)-4-methyl-
• 4-(4-chlorophenyl)-5-methyl-1H-imidazole
• 5-(4-Chlorophenyl)-4-methyl-1H-imidazole
• Lofemizol
• Lofemizol [INN-Spanish]
• Lofemizole [INN]
• Lofemizolum
• Lofemizolum [INN-Latin]
• Unii-D8G23Fpc3P
• Lofemizole

Lofemizole

CAS: 65571-68-8

Lofemizole

Purity: ≥95%

Molecular weight: 192.64g/mol

Ref: 54-BUP08516

Lofemizole

CAS: 65571-68-8

Lofemizole is an antagonist of CYP1A2.

Formula: C₁₀H₉ClN₂

Purity: 97.11%

Color and Shape: Solid

Molecular weight: 192.64

Ref: TM-T50053