CAS 6561-58-6

3β-Hydroxy-5-cholestenoic acid

Description:

3β-Hydroxy-5-cholestenoic acid, with the CAS number 6561-58-6, is a sterol derivative that plays a significant role in various biological processes. This compound is characterized by its steroid structure, which includes a hydroxyl group at the 3β position and a double bond between the 5 and 6 carbon atoms in the steroid nucleus. It is a key intermediate in the biosynthesis of bile acids and steroid hormones, contributing to cholesterol metabolism. The presence of the hydroxyl group enhances its solubility in polar solvents, while the hydrophobic steroid core influences its interactions with cell membranes and proteins. 3β-Hydroxy-5-cholestenoic acid is also involved in signaling pathways and may have implications in lipid metabolism and cardiovascular health. Its biological activity and potential therapeutic applications are subjects of ongoing research, particularly in the context of cholesterol-related disorders. Overall, this compound exemplifies the complexity and importance of sterols in human physiology and biochemistry.

Formula: C₂₇H₄₄O₃

InChI: InChI=1/C27H44O3/c1-17(6-5-7-18(2)25(29)30)22-10-11-23-21-9-8-19-16-20(28)12-14-26(19,3)24(21)13-15-27(22,23)4/h8,17-18,20-24,28H,5-7,9-16H2,1-4H3,(H,29,30)/t17-,18?,20+,21+,22-,23+,24+,26+,27-/m1/s1

InChI key: InChIKey=WVXOMPRLWLXFAP-AMQKJUDNSA-N

SMILES: C[C@@]12[C@]([C@]3([C@@]([C@]4(C)C(=CC3)C[C@@H](O)CC4)(CC1)[H])[H])(CC[C@@]2([C@@H](CCCC(C(O)=O)C)C)[H])[H]

Synonyms:

• (3β)-3-Hydroxycholest-5-en-26-oic acid
• 3β-Hydroxy-5-cholestenoic acid
• 3β-Hydroxycholest-5-en-26-oic acid
• 3β-Hydroxycholest-5-en-27-oic acid
• Cholest-5-En-26-Oic Acid, 3-Hydroxy-, (3Beta)-
• Cholest-5-en-26-oic acid, 3-hydroxy-, (3β)-
• Cholest-5-en-26-oic acid, 3β-hydroxy-
• 3-hydroxy-5-cholestenoic acid
• 3-BETA-HYDROXYCHOLEST-5-EN-26-OICACID
• -Hydroxycholest-5-en-26-oic Acid
• 3-Hydroxycholest-5-en-26-oic Acid

3β-hydroxy-5-Cholestenoic Acid

CAS: 6561-58-6

Formula: C₂₇H₄₄O₃

Purity: 97%

Color and Shape: Solid

Molecular weight: 416.6365

Ref: IN-DA00EFA2

3β-hydroxy-5-Cholestenoic Acid

CAS: 6561-58-6

3β-hydroxy-5-Cholestenoic Acid is one of the metabolites of cholesterol found in high concentrations (40-80 ng/ml) in human circulation.

Formula: C₂₇H₄₄O₃

Color and Shape: Solid

Molecular weight: 416.64

Ref: TM-T36124

3β-Hydroxy-5-cholestenoic Acid

Controlled Product

CAS: 6561-58-6

Applications A metabolite of Cholesterol. Elimination of Cholesterol in human endothelial cells.
References Prasad, V., et al.: J. Steroid Biochem., 21, 733 (1984), Duane, W., et al.: J. Clin. Invest., 92, 911 (1993), Lehmann, J., et al.: J. Biol. Chem., 272, 3137 (1997), Setchell, K., et al.: J. Clin. Invest., 102, 1690 (1998), Song, C., et al.: Endocrinology, 141, 4180 (2000),

Formula: C₂₇H₄₄O₃

Color and Shape: Neat

Molecular weight: 416.64

Ref: TR-H917500

3β-Hydroxy-5-cholestenoic Acid

CAS: 6561-58-6

Formula: C₂₇H₄₄O₃

Molecular weight: 416.65

Ref: ST-EA-CP-C71048