CAS 65666-07-1

Silymarin

Description:

Silymarin is a complex mixture of flavonolignans extracted from the seeds of the milk thistle plant, Silybum marianum. It is primarily composed of silybin, silydianin, and silychristin, which are known for their antioxidant and hepatoprotective properties. Silymarin is commonly used in herbal medicine, particularly for liver health, as it is believed to promote liver regeneration and protect against toxins. The substance exhibits anti-inflammatory and free radical-scavenging activities, making it a subject of interest in various therapeutic applications. Silymarin is typically administered in the form of capsules or tablets, and its bioavailability can be influenced by factors such as formulation and dosage. While generally considered safe, it may cause mild gastrointestinal side effects in some individuals. As with any supplement, it is advisable to consult healthcare professionals before use, especially for those with underlying health conditions or those taking other medications. Overall, silymarin is recognized for its potential health benefits, particularly in supporting liver function and overall wellness.

Formula: C₂₅H₂₂O₁₀

InChI: InChI=1/C25H22O10/c1-32-17-6-11(2-4-14(17)28)24-20(10-26)33-16-5-3-12(7-18(16)34-24)25-23(31)22(30)21-15(29)8-13(27)9-19(21)35-25/h2-9,20,23-29,31H,10H2,1H3/t20-,23-,24-,25+/m0/s1

InChI key: SEBFKMXJBCUCAI-UHFFFAOYSA-N

SMILES: COC1=C(C=CC(=C1)C2C(OC3=C(O2)C=C(C=C3)C4C(C(=O)C5=C(C=C(C=C5O4)O)O)O)CO)O

Synonyms:

• (2R,3R)-3,5,7-trihydroxy-2-[(2R,3R)-3-(4-hydroxy-3-methoxyphenyl)-2-(hydroxymethyl)-2,3-dihydro-1,4-benzodioxin-6-yl]-2,3-dihydro-4H-chromen-4-one
• (2R,3R)-3,5,7-trihydroxy-2-[(2S,3S)-3-(4-hydroxy-3-methoxyphenyl)-2-(hydroxymethyl)-2,3-dihydro-1,4-benzodioxin-6-yl]-2,3-dihydro-4H-chromen-4-one
• 2,3-Dihydro-3-(4-hydroxy-3-methoxyphenyl)-2-(hydroxymethyl)-6-(3,5,7-trihydroxy-4-oxobenzopyran-2-yl)benzodioxin
• Apihepar
• Darsil
• Flavobion
• Karsilin
• Laragon
• Legalon
• Legalon 70
• Milk Thistel P.E.
• Milk Thistle Extract
• Pluropon
• Silarin
• Silepar
• Silibinin
• Silirex
• Silistrong
• Silmar
• Silybin
• Silybon
• Silybum Extract
• Silybum marianum
• Silymarin Group
• Silystrong
• Silymarin
• Milkthistleextract/Silymarin
• SILYCHRISTIN SNAP-N-SHOOT 0.1mg/mL(P)
• Silybummarianumseedextract,fluid
• SILYBIN SNAP-N-SHOOT 0.1mg/mL(P)
• MilkthistleP.E.exsemencardui
• silybin or silybinin
• SILYMARINEXTRACT
• Silybummarianumextract,seed
• Milkthistleseedextract,fluid=Silymarin/Silybin
• SILYBIN(P)
• Milkthistleseedextract,powder=Silymarin/Silybin
• MILK THISTLE
• SILYBIN(MIX)(RG)

Silymarin

CAS: 65666-07-1

Formula: C₂₅H₂₂O₁₀

Purity: 80%

Color and Shape: Solid

Molecular weight: 482.4362

Ref: IN-DA01CCHW

Silymarin

CAS: 65666-07-1

Silymarin

Formula: C₂₅H₂₂O₁₀

Purity: 80%

Color and Shape: Solid

Molecular weight: 484.44

Ref: 54-OR1030020

Silymarin

CAS: 65666-07-1

Silymarin

Formula: C₂₅H₂₂O₁₀

Purity: ≥95%

Molecular weight: 482.44

Ref: 54-BUP18015

Silymarin (>80%)

CAS: 65666-07-1

Applications Silymarin a flavonolignan complex extracted from milk thistle, has been shown to provide cytoprotective, antioxidant and hepatoprotective effects. Provides extracts such as (+)-taxifolin as an inhibitor of β-amyloid aggregation.
References Gharagozloo, M. et al.: Int. Immunopharmacol., 16, 243 (2013); Sato, M. et al.: Biosci. Biotech. Biochem., 77, 1100 (2013);

Formula: C₂₅H₂₂O₁₀

Purity: >80%

Color and Shape: Neat

Molecular weight: 482.44

Ref: TR-S465895

Silymarin

CAS: 65666-07-1

Silymarin, a liver-aiding polyphenolic flavonoid, is extracted from milk thistle seeds.

Formula: C₂₅H₂₂O₁₀

Purity: 98%

Color and Shape: Solid

Molecular weight: 482.441

Ref: TM-T6670

Silymarin

CAS: 65666-07-1

Color and Shape: Yellow to brown powder

Ref: 7W-GW7248

Silymarin

CAS: 65666-07-1

Silymarin is a flavonoid complex, an active component derived from the seeds of the milk thistle plant, Silybum marianum. This product is primarily obtained through extraction processes that isolate the mixture of flavonolignans, which include silybin, silydianin, and silychristin. The mode of action of silymarin involves its activity as an antioxidant, inhibiting lipid peroxidation and scavenging free radicals. It also enhances protein synthesis in hepatocytes and stabilizes cell membranes, preventing the entry of toxins into the cells.

Formula: C₂₅H₂₂O₁₀

Purity: Min. 30 Area-%

Color and Shape: Powder

Molecular weight: 482.4

Ref: 3D-FS180849