CAS 65753-47-1

2-chloro-3-(trifluoromethyl)pyridine

Description:

2-Chloro-3-(trifluoromethyl)pyridine is a heterocyclic organic compound characterized by a pyridine ring substituted with a chlorine atom and a trifluoromethyl group. The presence of the chlorine atom at the 2-position and the trifluoromethyl group at the 3-position significantly influences its chemical properties, including its reactivity and polarity. This compound is typically a colorless to pale yellow liquid or solid, depending on the temperature and purity. It exhibits moderate solubility in organic solvents and is relatively stable under standard conditions. The trifluoromethyl group enhances its lipophilicity and can affect its biological activity, making it of interest in pharmaceutical and agrochemical research. Additionally, 2-chloro-3-(trifluoromethyl)pyridine can participate in various chemical reactions, such as nucleophilic substitutions and coupling reactions, making it a valuable intermediate in organic synthesis. Safety precautions should be taken when handling this compound, as it may pose health risks and environmental hazards.

Formula: C₆H₃ClF₃N

InChI: InChI=1S/C6H3ClF3N/c7-5-4(6(8,9)10)2-1-3-11-5/h1-3H

InChI key: InChIKey=RXATZPCCMYMPME-UHFFFAOYSA-N

SMILES: C(F)(F)(F)C1=C(Cl)N=CC=C1

Synonyms:

• 2,3-Ctf
• 2-Chloro-3-trifluoromethylpyridine
• 2-Chloro-3-trifuoromethylpyridine
• 3-Chloro-4-(Trifluoromethyl)Pyridine
• 3-Trifluoromethyl-2-chloropyridine
• 4-Chloro-3-(Trifluoromethyl)Pyridine
• Pyridine, 2-chloro-3-(trifluoromethyl)-
• 2-Chloro-3-(trifluoromethyl)pyridine
• 2-CHLORO-3-(TRIFLUOROMETHYL)PYRIDINE, 97
• BUTTPARK 45\10-29
• 2-Chloro-3-Trifluoromethylpyridine ,98%
• 2-Chloro-3-(trifluoromethyl)pyridine 95%

2-chloro-3-(trifluoromethyl)pyridine

CAS: 65753-47-1

Formula: C₆H₃ClF₃N

Purity: 98%

Color and Shape: Solid

Molecular weight: 181.5429

Ref: IN-DA00337C

2-Chloro-3-(trifluoromethyl)pyridine

CAS: 65753-47-1

2-Chloro-3-(trifluoromethyl)pyridine

Formula: C₆H₃ClF₃N

Purity: 98%

Color and Shape: white/colourless crystals

Molecular weight: 181.54g/mol

Ref: 54-PC2075

2-Chloro-3-trifluoromethylpyridine

CAS: 65753-47-1

Formula: C₆H₃ClF₃N

Molecular weight: 181.55

Ref: 7W-GK7254

2-Chloro-3-(trifluoromethyl)pyridine

CAS: 65753-47-1

2-Chloro-3-(trifluoromethyl)pyridine

Purity: 95%

Color and Shape: White Powder

Molecular weight: 181.54g/mol

Ref: 54-PC10438

2-Chloro-3-(trifluoromethyl)pyridine

CAS: 65753-47-1

Formula: C₆H₃ClF₃N

Purity: 98.0%

Color and Shape: Solid

Molecular weight: 181.54

Ref: 10-F009978

2-Chloro-3-(trifluoromethyl)pyridine

Controlled Product

CAS: 65753-47-1

Applications 2-Chloro-3-(trifluoromethyl)pyridine is a building block used to prepare various high affinity TRPV1 (VR1) vanilloid receptor antagonists.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Swanson, D., et al.: J. Med. Chem., 48, 1857 (2005); Rami, H., et al.: Bioorg. Med. Chem. Lett., 16, 3287 (2006)

Formula: C₆H₃ClF₃N

Color and Shape: White To Off-White

Molecular weight: 181.54

Ref: TR-C422230