CAS 65772-67-0

N-Piperacillinyl AMpicillin

Description:

N-Piperacillinyl Ampicillin, identified by its CAS number 65772-67-0, is a semi-synthetic antibiotic that combines the properties of two penicillin derivatives: piperacillin and ampicillin. This compound exhibits a broad spectrum of antibacterial activity, particularly against Gram-positive and Gram-negative bacteria, making it effective in treating various infections. Its mechanism of action involves inhibiting bacterial cell wall synthesis, leading to cell lysis and death. The presence of the piperacillin moiety enhances its stability against certain beta-lactamases, which are enzymes produced by some bacteria to resist penicillin antibiotics. N-Piperacillinyl Ampicillin is typically administered via injection and is often used in clinical settings for serious infections, including those caused by resistant strains. As with other beta-lactam antibiotics, it may cause allergic reactions in some individuals, and its use should be monitored for potential side effects, including gastrointestinal disturbances. Overall, this compound represents an important tool in the antibiotic arsenal, particularly in treating multi-drug resistant infections.

Formula: C₃₉H₄₄N₈O₁₀S₂

Synonyms:

• Piperacilin EP Impurity D
• N-Piperacillinyl AMpicillin
• Piperacillin Sodium EP Impurity D
• Piperacillin EP Impurity D
• Piperacillin Impurity D(EP)(Piperacillin+Ampicillin)
• 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 6-[[[[[6-[[[[(4-ethyl-2,3-dioxo-1-piperazinyl)carbonyl]amino]phenylacetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]hept-2-yl]carbonyl]amino]phenylacetyl]amino]-3,3-dimethyl-7-oxo-, [2S-[2α[S*(2R*,5S*,6S*)],5α,6β(S*)]]- (9CI)
• Piperacillin Impurity 4(EP Impurity D)
• Piperacillin ImpurityⅡ:Impurity D(N-Piperacillinyl Ampicillin
• 6β-((R)-2-{6β-[(R)-2-(4-ethyl-2,3-dioxo-piperazine-1-carbonylamino)-2-phenyl-acetylamino]-penicillanoylamino}-2-phenyl-acetylamino)-penicillanic acid
• [2S-[2α[S*(2R*,5S*,6S*)],5α,6β(S*)]]-6-[[[[[6-[[[[(4-Ethyl-2,3-dioxo-1-piperazinyl)carbonyl]amino]phenylacetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]hept-2-yl]carbonyl]amino]pheny

Piperacillinylampicillin

CAS: 65772-67-0

Nucleic acids and their salts, whether or not chemically defined; other heterocyclic compounds, nesoi

Formula: C₃₉H₄₄N₈O₁₀S₂

Color and Shape: White Powder

Molecular weight: 848.26218

Ref: 45-1A06570

Piperacillin EP Impurity D

CAS: 65772-67-0

Formula: C₃₉H₄₄N₈O₁₀S₂

Molecular weight: 848.95

Ref: 4Z-P-743

N-Piperacillinyl Ampicillin

CAS: 65772-67-0

Impurity Piperacillin EP Impurity D
Applications N-Piperacillinyl Ampicillin (Piperacillin EP Impurity D) is an impurity of Piperacillin (P479950), a β-lactam antibiotic.
References Saikawa, I. et al.: Yakug. Zas., 97, 980 (1977);

Formula: C₃₉H₄₄N₈O₁₀S₂

Color and Shape: Neat

Molecular weight: 848.94

Ref: TR-P479960

N-Piperacillinyl ampicillin

CAS: 65772-67-0

N-Piperacillinyl ampicillin is a drug product that is used for research and development. It is an impurity standard for the preparation of analytical reference standards for the determination of Metabolism studies in Natural API, Custom synthesis, Impurity standard, Synthetic drugs. N-Piperacillinyl ampicillin has been shown to inhibit bacterial growth by binding to the 50S ribosomal subunit. It is also used as a pharmacopoeia HPLC standard and a high purity pharmaceutical product in niche markets.

Formula: C₃₉H₄₄N₈O₁₀S₂

Purity: Min. 95%

Molecular weight: 848.9 g/mol

Ref: 3D-QCA77267

Piperacillin EP Impurity D

CAS: 65772-67-0

Formula: C₃₉H₄₄N₈O₁₀S₂

Molecular weight: 848.95

Ref: ST-EA-CP-P107052